everyone in earlier posts seemed to agree that it was not wise to take accutane while on a cycle since it put too much stress on the liver. however, i wonder if it really is THAT stressful on the liver.

dan duchaine recommends to take it along with really toxic cycles in his "underground steroid handbook II"

decibel: I think it is very SAFE not to take during a cycle. That said I am doing it. Why? because I have talked to people that have done it and researched my ass off and I dont *personally think* it will be bad. Read up on it and you will see the stress on the liver isn't bad, it is there but I have a feeling your last cycle might have been worse. As far as duchaine goes, I don't know about that. I wouldnt recomend people do it on a cycle, but if your like me and a cycle gets in the way I dont think it will be too bad - excpet for Mr A Bomb up there heheh.

Keep in mind I am not a doctor, all I did was get first hand thoughts/advice and read all I could on accutane and side effects.

Make the decision on your own. Obviously if I think its good for me, I must think I am relatively safe.

Some quick hits on Accutane from experience (and Slopain has covered some of these accurately):

Be PATIENT - it will take a solid 2 months to work effectively (maybe more if you have severe acne)

Get some Carmex or other lip balm. The dry lips are really the only bad side of this.

Sometimes you will get dry patches of skin. Get a good skin cream. I recommend Galderma it is the shit.

If you wear contacts while on Accutane, wash them a lot and keep your eyes watered with drops - you may get some dry eyes while on Accutane.

You will feel itchy and dry at times all over...deal with it, it's no big deal.

Stick it out no matter how shitty you might feel in the first 2 months or so, it will work and it is an awesome feeling when it does.

Also - it is not as liver toxic as it is played out to be. BUT...combining it with strong liver toxic substances such as ALCOHOL and EXSTASY are not good ideas. Try to avoid these things if possible...why tax your liver more than you have to? As far as the juice goes, I PERSONALLY would not take any of the 17-akyl orals at all. This is just too much of a load in my opinion. Injectables should be no problem with Accutane (and I have this advice from a doctor that understands the liver function effect of injectable testosterone).

Hope that helps a bit...

During the six months of Accutane I stayed off AS. If you plan to do AS and accutane simultaneously, its simple enough to have the routine liver function tests run. Dont speculate your body is tolerating both well. It depends on your AS dosages, your accutane dosages, the oral AS you take, how much liquor you consume, what other assorted liver taxing things you do.

I'm sure you can cleverly convince the Dr. to test your liver function during the accutane course. (typically 6 months). In fact, I agree with Slopain who said that after 30 days the Dr. is going to run these tests routinely. That was what was done in my case and it is the normal course of treatment on this drug.

What you want to make sure is that you pass the tests. If you jump into a cycle and levels are overly elevated you will have to tell him or he will pull you off Accutane speculating that you arent tolerating the drug. Its your choice, but your doctor will test your liver functions.

I'd echo djdiesel's advice to stay away from 17alphas. Primo depot inj and anavar (if you can afford it) would be real safe. (effective is another issue)