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  Clen mechanism by which it works?

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Author Topic:   Clen mechanism by which it works?
chestyII

Elite Bodybuilder

Posts: 954
From:Phx,AZ
Registered: Feb 2000

posted August 19, 2000 05:50 PM

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Okay, I know it works during a cutting cycle, by raising metabolism, temp a little, but what is the exact mechanism by which it helps retain gains at end of cycle?

chesty

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The Ranger

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From:Look behind you
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posted August 19, 2000 06:04 PM

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Chesty,
Clen is classified as a Beta-2-Symphatomimetic....simply put....it has very good anti-catabolic effects.....

Ephedrine is similar, though not as powerful, and has some anti-catabolic effects as well and is classified in the same group of Sympathomimetics(Generally found in medicine fo Asthma user's)...Peace!!

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markaveli222

Amateur Bodybuilder

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posted August 19, 2000 06:05 PM

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I will bump this for you. I would like to know the answer to this also. I was thinking of using some clen after my cycle is over.


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Twisted_Steel

Elite Bodybuilder

Posts: 615
From: South Carolina
Registered: Apr 2000

posted August 19, 2000 06:07 PM

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I am of the opinion that those who believe that the use of clenbuterol post cycle as a means to solidify newly acquired gains via anabolism are being misguided. Any anabolic conclusions drawn from the use of
Clenbuterol were derived from the
administration of this product in cattle, who have an abundance of Beta-2/3 receptors.
Compounds that upregulate beta-3 adrenergic
receptors, which are specific to adipose cells, cause a 10-30% increase in
metabolic rate. The realization of adipos tissue is the ultimate end realized by its users. Using this product for any other purpose would be a waste. Without going into gross mind dumbing detail, I hope this helped.


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[This message has been edited by Twisted_Steel (edited August 19, 2000).]


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2Thick

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posted August 19, 2000 06:13 PM

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There are scores of experiments that show mice in HLS have considerably less wasting when clen is introducted. And they are not cattle.

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chestyII

Elite Bodybuilder

Posts: 954
From:Phx,AZ
Registered: Feb 2000

posted August 19, 2000 06:15 PM

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Ok boys and girls what is that translated into simpleton english (marine jargon)

If it is anti-catabolic in cattle, why wouldn't it have similar effects in humans. Even if we have a difference (sp) in beta 2/3 recptors.

I will be the guinne (sp) pig since I am starting clen today as post cycle cycling it with Xenadrine. We will see what gains remain at the end of eight weeks.

chesty

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The Ranger

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posted August 19, 2000 06:18 PM

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Khule Chesty....Go fer it Bro!!!

Damn Twisted S......" You blinded me with Science..." Heh heh heh....Khule as Well I might add...!!!

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Twisted_Steel

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From: South Carolina
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posted August 19, 2000 06:20 PM

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Im sure you pretty much got the jist of it all Chest, Clen is anti-catabolic, how? By supressing cortisol levels? No, it doesnt do this. Use it to increase resting metabolism. Nothing more Doses exceeding 120mcg are genrally considered overkill, humans simply lack sufficient receptor sights for this product.

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[This message has been edited by Twisted_Steel (edited August 19, 2000).]


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2Thick

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posted August 19, 2000 06:23 PM

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Twisted,

How do you expain the research on mice?

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2Thick

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posted August 19, 2000 06:27 PM

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Also it reduces the rate at which protein is broken down in the muscle cell and not necessarily suppresses cortizone levels.

I think your research is outdated. I will go through some files and find you some updated research.

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Twisted_Steel

Elite Bodybuilder

Posts: 615
From: South Carolina
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posted August 19, 2000 06:27 PM

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http://journals.endocrinology.org/

My uncle doesn't subscribe to Sports Illustrated, what can I say!

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2Thick

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posted August 19, 2000 06:31 PM

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Clen is not a hormone compound, so it may not be the main focus in the area of endocrinology.

I would imagine the American Journal of Physiology would be a better resource.

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chestyII

Elite Bodybuilder

Posts: 954
From:Phx,AZ
Registered: Feb 2000

posted August 19, 2000 06:34 PM

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Keep this one at the top, it is interesting as well as beneficial.

chesty

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The Ranger

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posted August 19, 2000 06:45 PM

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How I do luv these professional debates without the flames.....this is Khule!!!!!!

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cockdezl

Amateur Bodybuilder

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posted August 19, 2000 06:48 PM

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Clen is mostly a beta-2 agonist, which causes an increase in thermogenesis by increasing cAMP levels in its target cells. In adipocytes, this causes a release of free fatty acid from the cell, which is then used by other cells (muscle) for energy. When free fatty acids increase in the blood, there is a decrease in insulin sensitivity. This decrease is anti-catabolic since it is protective against catabolism of muscle tissue for energy.


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