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 Will finasteride(Propecia 1mg) effect gains while not on AS?
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| Author | Topic: Will finasteride(Propecia 1mg) effect gains while not on AS? |
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Philip Amateur Bodybuilder (Total posts: 6) |
posted August 05, 2000 11:17 PM
  
Some say it will make it harder to put on size and some say it may even slightly improve gains(15%test level raise on average posted by Hominid June 28/00 under topic "a different type of hairloss problem"). I take 1mg a day for MPB.Should I stop? I have looked at archived topics but found much conflicting info. IP: Logged |
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Monster Pro Bodybuilder (Total posts: 234) |
posted August 06, 2000 01:07 AM
Hmmmm, there isnt a cut and dry answer to this, but here it goes. Proscar and propecia should stop DHT which is the hair-killer. Some drugs strongly convert to DHT, which is still useable by the body, but is hell on the hair. So if you take a drug that relies on a strong conversion to DHT to give you the effects it touts. Off the top of my head, Winstrol Depot and Test Cypionate are two that do. So the Proscar would interfere with them. I'll give you mty secret 100% guaranteed method to solve this problem. Tested and approved by me. Its the one I use and endorse... I shaved my head. Heh heh... hope that was some help (the non-shave your head part, that is) IP: Logged |
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bigpun Amateur Bodybuilder (Total posts: 41) |
posted August 06, 2000 01:53 AM
bump this, I'm really interested in seeing if someone has a good answer- I've been wondering the same thing for myself. IP: Logged |
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Hominid Amateur Bodybuilder (Total posts: 65) |
posted August 07, 2000 12:21 AM
Philip, yes you're right I did metion here that finasteride results in an average increase in testosterone of something like 15%. The reason is simply that by inhibiting the 5-alpha-reductase enzyme, less test gets converted to DHT. Should this translate to more gains? Maybe! It's not clear because there might be some kind of synergistic effect between T and DHT in muscle tissue, though personally I doubt it. I have uncovered academic research that shows DHT has very low affinity for androgen receptors in muscle tissue, which implies very little anabolic effect. DHT has extremely high affinity for nadrogen receptors in scalp tissue, however, and this is why it is so much worse than T with regard to hair loss. Monstor I believe you are mistaken; winny does not convert to DHT or depend on DHT in any way. It is merely similar to it molecularly. Also all test from all test esters (enanthate, cypionate, whatever) is subject to conversion to DHT in the same fashion. And no test from any ester depends on the conversion to DHT for its anabolic effect more than any another, if any do at all. Personally I take 1 mg finasteride each day while on cycle or off, and I've yet to find any evidence that my cycles are less effective as a result of it. [This message has been edited by Hominid (edited August 07, 2000).] IP: Logged |
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bsjohnson Pro Bodybuilder (Total posts: 177) |
posted August 07, 2000 12:35 AM
Hey Hominid, not to say your wrong but i was just wondering about winny. YOu said that it doesnt convert to DHT. Just wondering were you got your info from. B/c i read in Pump mag. that it converts,and i read several old post that said it converts. Just wondering b/c i'm about to take some winny very soon,and just wondering if i will lose any hair.NO flame just heard several ppl. say it converted, just wondering. Thanks bro. IP: Logged |
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TonyDelk Amateur Bodybuilder (Total posts: 24) |
posted August 07, 2000 12:45 AM
C'mon Bros. Use Flutamide and/or Spironolactone while on any AAS and you will have almost total adrogen receptor blockage.(in the scalp/follicles.) Of course it really doesn't matter if you have the MPB gene anyway. The androgen receptor blockers will only slow down a process which is inevidible. There are several good posts in the archives of recent interest about hair loss and AAS. Go read them. Finasteride is not worth the cost in my book, unless you are only going to use a Testosterone for your cycles. No time to explain. Good luck. TD IP: Logged |
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Hominid Amateur Bodybuilder (Total posts: 65) |
posted August 07, 2000 12:48 AM
Winny can cause hair loss but not because it converts to DHT. Only testosterone converts to DHT. Winny can cause hair loss because it binds to the androgen receptors in the scalp just as does DHT. Any and all androgens can contribute to male pattern baldness -- even DHEA. As for where I learned this, I really don't know for certain. I learned a lot from reading medline research abstracts and articles by the likes of Bill Roberts. I manage a mailing list for people interested in improving general health and increasing life-span through supplements and other things (including steroids). The mailing list is called "longevity". On that mailing list I debated these issues of DHT/anabolism/hairloss/finasteride in great detail recently. I uncovered a lot of research and posted it there. Anyone who might like to join that discussion group should send an email to IP: Logged |
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Hominid Amateur Bodybuilder (Total posts: 65) |
posted August 07, 2000 12:58 AM
I agree that topical spironolactone is the best general hair loss solution for AS users. Spiro blocks all androgens while finasteride does nothing to prevent hair loss from winny or from any other steroid aside from testosterone/DHT. However most people stack with substantial amounts of test, so finasteride is usually still a good idea. Don't take spiro orally, however. It will turn you into a woman. IP: Logged |
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scott825 Pro Bodybuilder (Total posts: 645) |
posted August 07, 2000 01:23 AM
Phillip I was thinking of getting some propecia also but I read that the main side effectb is Gyno so I changed my mind. ------------------ Bros before Hos IP: Logged |
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Hominid Amateur Bodybuilder (Total posts: 65) |
posted August 07, 2000 01:34 AM
gyno is rare side effect of Propecia (finasteride). It occurs because of the increase in testosterone, some of which is aromatized to estradiol. It is the exact same gyno risk that we take each time we inject testosterone directly. It's rare side effect however compared to gyno from AS use. The more troubling side of finasteride is reduced libido, which occurs in roughly 3 to 5 percent of men. IP: Logged |
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macrophage69alpha Moderator (Total posts: 1473) |
posted August 07, 2000 02:23 AM
DHT- like most highly androgenic steroids, has a definite effect on the CNS- taking finasteride (which by inhibiting the 5a-reductase enzymes will result in less dht being produced) may result in less forceful muscle contractions and may in the long run hurt your gains (especially strength gains). however the loss is probably minimal- I also feel that the topical anti-androgen route is the way to go. Peace ------------------ IP: Logged |
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Philip Amateur Bodybuilder (Total posts: 6) |
posted August 07, 2000 04:42 PM
Thanks for you're time I asked my Doc if Propicia would have any negative effects on mussle growth before i started taking it and he just said "NO".I don't think they even know or care about stuff like that.Lucky we have a place like this to get info from IP: Logged |
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