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 Difference between T3 and T4 thyroid hormones
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| Author | Topic: Difference between T3 and T4 thyroid hormones |
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Eramthgin Pro Bodybuilder (Total posts: 198) |
posted June 18, 2000 01:38 AM
  
I've looked and can't find the difference. Anyone know??? IP: Logged |
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Maverik Amateur Bodybuilder (Total posts: 44) |
posted June 18, 2000 01:40 AM
From what I know t4 has to be converted to t3 before it has any effect. It is better to use t3 because it is more direct and avoids this conversion. IP: Logged |
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CornFed Pro Bodybuilder (Total posts: 216) |
posted June 18, 2000 01:41 AM
T4 is just a precursor to T3. T3 is much much more effective. There is not much evidence that T4 has positive effects on fat burning.... check the archives there is plenty about in there.... IP: Logged |
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bignate73 Pro Bodybuilder (Total posts: 926) |
posted June 18, 2000 01:53 AM
hey bro, hit up www.about.com and search "t3" and "synthroid" and you should find all the info you could want probably. IP: Logged |
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Mojo Pro Bodybuilder (Total posts: 341) |
posted June 18, 2000 02:03 AM
Good site nate IP: Logged |
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NoviceJuicer Pro Bodybuilder (Total posts: 185) |
posted June 18, 2000 02:23 AM
In a bit of a nutshell....thyroglobulin is produced in the liver by combining the protein globulin with L-tyrosine and some other junk. This is transported to the thyroid gland where under the stimulation of TSH (thyroid stimulating hormone) it is altered into T4 (Thyroxine). T4 itself is a metabolic stimulator although a weak one. T4 is converted, primarily in the peripheral tissues into T3 (Triiodothyronine - it has three or "tri" iodine componants attached to it along with some other junk). That is why the nutritional supplements of L-tyrosine and iodine can be valuable ways to stimulate ones own natural thyroid production. IP: Logged |
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cockdezl Pro Bodybuilder (Total posts: 169) |
posted June 18, 2000 12:46 PM
NOVICE's explanation is on the mark. T4 is highly bound to serum TBG and other carrier proteins, while T3 is not. T4 is a reserve form for T3, it requires conversion into T3 to display any significant activity. T3 is approximatly 5 times more potent in activity than T4. Also, T4, because of its affinity to TBG, is retained in the body longer while T3 is readily excreted. As for Tyrosine and Iodine supplementation, this is useless, in my opinion, since virtually no one in the US is deficient in these two and the addition of them in the diet will not drive the reaction forward. IP: Logged |
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NoviceJuicer Pro Bodybuilder (Total posts: 185) |
posted June 18, 2000 01:56 PM
Cockdezl, I had never thought about how readily T3 is excreted, but it makes sense. That gives me a slightly new perspective on T3 thanks This is not meant to be a flame at all Cockdezl, and I will admit I just learned something from you but I would have to disagree with you on the L tyrosine and iodine. It is true that it is supplemented into our diet, but people have such varying nutritional demands. Trying to compartmentalize them into the RDA (ridiculous daily requirements) is ridiculous because all nutritional needs vary from person to person and time to time. How much water does a person need? If they are in Arizona working outdoors and eating a dry diet they needs pershaps several gallons. If they are in a humid environment, eating lots of fruit and not exerting themselves then a glass or two a day may suffice. many people need huge (gallons) of L tyrosine and iodine to function. To say that USA diets provide adequate L tyrosine and iodine is like saying they provide adequate vitamin C - if our diets provided adequate vitamin C then we would not have so much osteoporosis. IP: Logged |
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cockdezl Pro Bodybuilder (Total posts: 169) |
posted June 18, 2000 04:45 PM
"To say that USA diets provide adequate L tyrosine and iodine is like saying they provide adequate vitamin C - if our diets provided adequate vitamin C then we would not have so much osteoporosis." NOVICE, I agree with your statement that there is a biochemical individuality from person to person, but as I said, in my opinion, I doubt there is any real deficiencies in tyrosine and iodine. My reasoning is that 1.) the US eats more meat than most countries, so the source for tyrosine is covered, and the little that would be supplemented should be negligable, unless one is a vegan, but we could give a shit about them, and 2.) salt is iodized in the US and most people eat too much salt. This may be a problem in dieting BB's who are restricting sodium, so this may be the exception to my argument. Your argument is best suited for those micronutrients that have been removed from food or are destroyed in processing. Tyrosine and iodine are not readily damaged or removed in processing. I am a firm believer that our food IS deficient in many of the essential nutrients required for optimal health, therefore I am a pill junkie. Again, this is my opinion and I do not mind being corrected. Also, I have noticed your posts to be very informative and factually based and therefore have enjoyed your contributions to this board. IP: Logged |
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susthead Pro Bodybuilder (Total posts: 165) |
posted June 18, 2000 06:32 PM
get ya self some tricana m8 its kewl its mild not much risk and works wicked theres a supplement in the us call triax that is the same as tricana not triax 2 tho thats shit you want triax do 10 weeks like this and the results will be excellent 1: 1 tab day IP: Logged |
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NoviceJuicer Pro Bodybuilder (Total posts: 185) |
posted June 18, 2000 09:22 PM
Out of curiosity - any opinions on Armour thyroid and the risk of harming the thyroid? Cockdezl, vitamin C is another supplements supplemented to probably a greater extent than iodine - actually much greater - and yet we see such signs of extreme vitamin C deficiency as osteoporosis as an epidemic. I know I have seen numerous before and after blood tests and seen the alteration in thyroid levels. Your argument sounds good, but I have seen it work so its hard to convince me based on logic. Up until recently medically speaking the common logic was steroids added no real benefit to athletic training - so I am kind of immune to standard medical thinking regarding many things. In fact that is why I come here more then I talk to MD's about testosterone and HGH - I think some on here know more on the subject then the medical "experts". It hard to compare book knowledge to real life experience in anything from mechanics to cooking. IP: Logged |
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