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 What/Why/When: INSULIN: The answer
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| Author | Topic: What/Why/When: INSULIN: The answer | ||
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Elite Bodybuilder 
Posts: 1083 |
Your body releases insulin to dispose of unneeded sugar. While insulin is an extremely anabolic hormone (actually the most anabolic hormone known to man), there is a definite disadvantage with insulin spikes caused by too much sugar. Insulin triggers energy stores to open up and helps to shuttle nutrients into storage areas. Adipose cells readily accept nutrients to be stored as bodyfat shortly after the introduction of insulin. Insulin opens the �doors� in adipose for bodyfat storage for a very short period of time. It takes a high level of insulin to force open the adipose doors. Insulin doesn�t affect bodyfat storage as long as the insulin levels rise slowly and remain fairly consistent. Throughout the day, sugar consumption can spike insulin levels and induce bodyfat storage. Eating a high carb diet without sugars will cause a steady release of sugar into the system causing a high level of insulin release, but since the rate of release is steady, it does not trigger an �open door� in adipose for bodyfat storage but provides an extremely anabolic environment as the benefits of insulin are realized. Complex carbs are a much bigger molecule than simple sugars. They have many sugars bonded together. To turn complex carbs into glucose, they must be broken down. There is a series of steps that they must undergo to be broken down. Enzymes must be present to break each molecular bond of these polymers. All this takes a while to complete. By the time some of it is broken down into glucose, in the small intestines, some of it has already passed into the large intestine where absorption is almost completely ceased. This process allows for a slow and steady rate of glucose production that fuels the brain and muscles throughout the day without causing a release of insulin. This is very important because, as previously stated, you don�t want insulin in your body during a workout; you need its recipicle, blood sugars. Animals release natural sugar stores, glycogen, for energy. The body will regulate itself with insulin when it no longer needs the sugar in its system. It doesn�t matter whether the sugar comes from internal (from glycogen) or ingested sources (table sugar), insulin is released to counteract it. There will be rushes and fatigue with high consumption of sugars as your body tries to regulate itself. It can be almost impossible to workout when one�s blood sugar levels are low due to sugar consumption beforehand. Insulin signals the body to begin repair after a workout. Your body thinks that glycogen has been released when sugar is present in the bloodstream. Why? Glycogen (blood sugar) is released when your body meets high output demands. After strenuous activity, the body has to repair. When one is undergoing activity such as weightlifting, he needs energy, glucose from broken down glycogen. Insulin is released after the workout to counter the now not needed glucose level. When muscles sense the presence of insulin, they see that its time to begin healing and recuperation. Insulin �opens doors� in the muscles to accept nourishment and helps to shuttle in vital nutrients such as amino acids. Just imagine your muscle cells as having an irresistible attraction to insulin, a chemical attraction. The insulin wants to get into the muscle. What is so significant about insulin is its chemical make up. Its structure causes it to bond to nutrients. Nutrients include creatine, prohormones, anabolic hormones, some vitamins, minerals, glutamine, and other amino acids. This is the cause of the 45-minute window for taking supplements and refueling your body for the next workout. The body sucks up needed amino acids during this period. Remember, muscle tissue is made from the assimilation of various amino acids. So, to have protein synthesis within the muscles, your cells must have sufficient amounts of various amino acids. Glutamine is the biggest component of muscle fiber. Adequate glutamine is essential for the addition of new muscle. All of these nutrients are sucked into the cell for 45 minutes due to the increased amount of insulin in the body after a workout, and because the muscles themselves are �starving� for them, a phenomenon called intercellular thirst. With this in mind, you can see how ingestion of huge amounts of sugars after a workout is beneficial. Your body will have some insulin naturally released after the workout but the more, the better in causing a hormonal environment that�s good for forming new muscle. IGF-1 (insulin like growth factor), a Growth Hormone, is also released in the presence of insulin. Growth Hormone is what causes gigantism. That�s one factor in determining why some people are mesomorphs and others are ectomorphs. It�s why people like Andre �the Giant� don�t even have to work out to be huge, but if they do, they gain much more muscle than the normal person. The growth hormone is released by the pituitary gland. Think about this, what if you could have a spiked insulin level all throughout the day? You�ve already learned that you don�t want extra insulin just before a workout because it will hinder the breakdown of the muscle fibers. But imagine a 24-hour insulin spike. That would be the most anabolic environment one could ever hope to achieve. So how do you achieve that? Well that�s one of the biggest dilemmas faced in the underground world of competitive bodybuilding today. And in fact it�s one of the biggest reasons that bodybuilders are bigger, stronger, and more defined than bodybuilders ten years ago. They have employed the injection of artificial insulin. Imagine, all day long, almost everything that is consumed is converted into anabolic fuel. Insulin is more powerful than any steroid ever formulated. But it�s also the most dangerous. Bodybuilders inject incredible amounts daily. The pancreas may soon stop its own production of insulin and the body can become solely dependent upon the exogenous injections. One could cause himself to become a life long diabetic... No one really knows the effects that repeated artifical injections will have on a healthy pancreas. Well, this should show you the importance of insulin in the bodybuilding world. The main theme of insulin is: complex carbohydrates inadvertently cause a slow but steady release of insulin all day long. So, if you up your consumption of complex carbohydrates, you put your body into a more anabolic state without artificial insulin. Never drop carbohydrates from your diet no matter what you hear unless you want to end up fatter with more flab and less muscle than you did before you started your �diet.� People have made millions because they get a degree and come up with a new �diet� plan and sucker people into following it and inadvertently wreck their bodies in the long run. If you drop carbs, even though you consume vast amounts of protein, your body will not be as anabolic, and you will loose muscle. Cut back the fat from your diet and increase the complex carbs as high as you can. EAT EAT EAT. That�s how you loose weight. Not that everyone is looking to loose weight per se, but gaining muscle = loosing bodyfat. Muscle is the only mechanism by which to burn fat (except from heat that is produced through various means). I�ll reiterate upon one of the advantages of this 45-minute window. After strenuous activity, your body is more receptive for storing up energy as glycogen than any other time. Glycogen is not stored as fat. It�s stored in the glycogen stores. Ingestion of sugar at this time will allow it to be stored as energy to be consumed during the healing process as well as your fuel for the next day and the next workout. The body is most receptive within 30 minutes of a workout. After 45 minutes, it begins to taper off drastically. The protein and carbs that you consume after a workout would be more beneficial for you if they were in a liquid form, such as a whey protein drink or meal replacement shake. Solid food must sit in the stomach and wait on digestion before it will be sent to the small intestine where the needed nutrients will be absorbed. It�s a race against the clock. This is your critical time. About an hour to an hour and a half after a workout you can eat a good meal. To eat it before then will cause your sugars and proteins to have to sit in the stomach until the rest of the solid food can be broken down before it is absorbed. You don�t want to hinder the absorption of liquid proteins and sugars. Also, casienate (a protein supplement) should be avoided at this time due to the fact that stomach acids cause this protein to gel and it takes considerably longer for your stomach to digest it. Be careful not to ingest any sugars before your workout. You don�t want insulin in your system during a workout. This is for obvious reasons. Insulin depletes blood sugar. With low blood sugar, your can't make strong muscular contractions. You will be holding down your gas pedal for growth while you are holding down your brake for muscle breakdown. The only reason a muscle gets bigger is through the body adapting to stress by not only repairing the muscle from this breakdown, but repairing it to be MORE powerful than it was before. -Stew [This message has been edited by Stew Meat (edited April 23, 2001).]     | ||
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Freak 
Posts: 2681 |
So what is your take on insulin supplemenation? I love it as a bridge with glutamine and creatine. I am an experienced insulin user. Are you saying with the proper diet I can get the same results? I find that very hard to believe. ------------------ *** Dont email me asking for a source!!!!! *** "Catch a man a fish and he eats for a day, but if you teach a man to fish, he eats for a lifetime." | ||
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Elite Bodybuilder
Posts: 1083 |
Diet can't do what slin injections can. Diet can keep insulin levels high promoting an anabolic environment. For those who don't want to face the risks of exogenous insulin injections, maintaining an elevated insulin level will promote muscle gain. However, cardio must not be neglected or you'll start to put on fat as well as muscle. I use insulin myself...
[This message has been edited by Stew Meat (edited April 22, 2001).] | ||
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Freak
Posts: 2681 |
Yes, slin is amazing. I too put on fat. I will be doing 25mcg of t3 ed and cardio 2 times a week on my next bridge. I will be doing 10-12ius post workout and 5ius in the morning on non-workout days. ------------------ *** Dont email me asking for a source!!!!! *** "Catch a man a fish and he eats for a day, but if you teach a man to fish, he eats for a lifetime." | ||
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Elite Bodybuilder
Posts: 1316 |
Stew, Let us not forget the benefit of frequent, smaller meals as well. Along with sugar, protein and fat will elicit the insulin response. I agree with the window of opportunity that you mentioned, however, the logic of only ingesting simple forms of the macro nutrients (ones that need no real digestion to be absorbed) lends itself to contradiction. If we don't ingest some sort of complex foods with our initial post workout meal then we must wait for our "solid" meals to then be digested, thus making our muscles wait for an addition 3-4 hours before our next meal. ------------------ | ||
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Pro Bodybuilder 
Posts: 526 |
This is the best post I've read all month. It provides a good explanation for what I have observed on my own. How many of you guys know sugar junkies that consume relatively few calories, but still look like a tub of s&^t? One observation, Stew. You make a distinction between simple and complex carbs. Isn't glycemic index really what is important? I have heard that Wonder bread has a higher GI than some simple sugars. If this topic doesn't get much traffic, | ||
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Pro Bodybuilder
Posts: 526 |
Jersey boy, Perhaps there is a happy medium. Down the MRP immediately following the workout. Eat the meal 20 or so minutes later. I doubt the solid meal will slow the MRP digestion at that point. | ||
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Amateur Bodybuilder 
Posts: 227 |
Stew, Great post!!! Really informative and in-depth. Thanx for taking the time to write that up. Everyone should read this... BUMP. | ||
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Elite Bodybuilder
Posts: 1316 |
Zeke, I agree there is a happy and necessary medium. The glycemic index you mentioned DOES play a very important role in this whole discussion. The lower the more complex, thus the more slowly absorbed. For the sake of this discussion, I think Stew would encourage high glycemic foods immediately post workout and lower during the day to help facilitate the steady insulin levels of which he spoke. ------------------ [This message has been edited by jersey boy (edited April 23, 2001).] | ||
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Elite Bodybuilder
Posts: 1083 |
Solid foods should be avoided for 45 minutes post workout as they can interfere with sugar absorbtion. MRP shoudl be avoided as well as the fat in them will hinder sugar absorbtion. Eat a shit load of sugar (60-100g) within 20 minutes then hit WPI, then wait at least 45 minutes (best at over an hour) before you touch anything solid. -Stew | ||
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Freak
Posts: 2681 |
That is what I do already. I didnt do any research on it either. It was trial an error. I take 15 grams of glutamine with a big glass of cranberry/cherry juice and have a protein shake 10 mins later. Isopure zero carb, and the meal comes about 45 mins later. ------------------ *** Dont email me asking for a source!!!!! *** "Catch a man a fish and he eats for a day, but if you teach a man to fish, he eats for a lifetime." | ||
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Elite Bodybuilder
Posts: 1083 |
quote:
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Elite Bodybuilder
Posts: 1316 |
What is to done in the between the time of the first meal (post workout) and the final time of the long awaited digestion of the solid meal. This could take up to 4 hours before getting to the muscles for absorbtion. Would one be playing with the chance of going catabolic? The amino acids and glucose floating in the bloodstream needed for muscle reparation would then be used for other metabolic processes and thus hinder over all growth and supercompensation that we are all looking for. ------------------ | ||
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Elite Bodybuilder
Posts: 1316 |
Stew, Super point about the use of electolyte replacement as well! ------------------ | ||
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Elite Bodybuilder
Posts: 950 |
DAMN, THAT'S GOOD INFO. OKAY, HERE'S MY STORY: WHEN I FIRST STARTED LIFTING ABOUT TEN YEARS AGO I HAD A TERRIBLE DIET. TWO YEARS LATER AND AFTER DOING A LOT OF READING I WAS BASICALLY FOLLOWING A VERY STRICT DIET THAT WAS VERY LOW FAT/HIGH CARB/HIGH PROTEIN. ON THIS DIET, I MADE SOME OF THE BEST SIZE AND STRENGTH GAINS I EVER HAVE. HOWEVER, I NEVER COULD GET RIPPED, NO MATTER HOW MUCH FAT I CUT OUT OR HOW MUCH CARDIO I DID. SURE, I GOT BIGGER AND STRONGER FASTER THAN MOST OF MY FRIENDS WHO ALSO LIFTED DID, BUT I HELD MORE BODYFAT. AFTER A FEW YEARS THIS BECAME VERY DISCOURAGING. ABOUT THREE YEARS AGO I READ A BOOK CALLED "PROTEIN POWER" WRITTEN BY TWO CARDIOLOGISTS. IT MADE SENSE, SO I THOUGHT I'D GIVE IT A TRY. WELL, USING THIS NEW LOW CARB DIET WITH CIRCUIT TRAINING, I SAW MY ABS FOR THE VERY FIRST TIME! I RESPONDED INCREDIBLY TO THIS NEW DIET, LOSING A LOT OF BODYFAT AND VERY LITTLE MUSCLE. I WAS PRETTY STOKED, TO SAY THE LEAST. NOW, USING ANABOLICS, I'VE BEEN ABLE TO MAKE STEADY GAINS IN MUSCLE MASS STILL FOLLOWING A LOW CARB DIET. I'M WONDERING IF MY GENETICS GIVE ME UNUSUALLY HIGH LEVELS OF INSULIN TO START WITH. THERE ARE QUITE A FEW PEOPLE IN MY FAMILY WHO ARE OVERWEIGHT, AND ADULT ONSET DIABETES RUNS IN MY FAMILY, TOO. MOST PEOPLE THINK DIABETES IS A LACK OF INSULIN, BUT TYPE 2 (ADULT ONSET) DIABETES OCCURS WHEN PEOPLE HAVE TOO MUCH INSULIN FOR A LONG PERIOD OF TIME. BODYBUILDERS WHO SUPPLEMENT WITH SLIN SUFFER FROM THIS, AS STEW STATED. I'M THINKING THAT I MUST HAVE UNUSUALLY HIGH LEVELS OF INSULIN AS I AM ABLE TO MAINTAIN AN ANABOLIC STATE EVEN ON A NO CARB DIET. I GUESS I SHOULD LOOK AT THIS AS A BLESSING. I NEVER HAVE HAD A PROBLEM GETTER BIGGER, BUT I DO ENVY YOU GUYS WHO CAN KEEP A SIX PACK ALL YEAR ROUND AND EAT LIKE SHIT. NOT ME! I HAVE TO WORK MY ASS OFF AND FOLLOW A STRICT ASS DIET TO GET ABS STEW, DO YOU THINK SLIN INJECTIONS POST WORKOUT WILL WORK ON A LOW CARB DIET? SUPPOSE I DRANK A PROTEIN SHAKE AND THEN SHOT SOME SLIN FIFTEEN MINUTES POST WORKOUT. WHAT DO YOU THINK THE EFFECTS OF THIS WOULD BE? PEACE ALL AND HAPPY EATING! ------------------ NEWBIES, CLICK ON THE LINK BELOW AND GET YOUR QUESTIONS ANSWERED AT THESE FINE SITES. UPDATED WEEKLY | ||
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Elite Bodybuilder
Posts: 1083 |
Slin will probably be most beneficial to those who are on a low carb diet.
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Elite Bodybuilder
Posts: 950 |
I THINK YOU'RE RIGHT, STEW. ITS EITHER THAT OR SLAM A SPORTS DRINK FOLLOWED BY A WPI DRINK. I'M GOING TO GIVE SLIN A TRY. THIS GAME NEVER GETS BORING, DOES IT? THANKS BRO. I WISH WE HAD MORE TEACHERS ON THE BOARD ------------------ NEWBIES, CLICK ON THE LINK BELOW AND GET YOUR QUESTIONS ANSWERED AT THESE FINE SITES. UPDATED WEEKLY | ||
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Elite Bodybuilder
Posts: 1083 |
quote:
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Elite Bodybuilder
Posts: 1402 |
Great post Stew! Very informative, I don't think I would mess with that for the time being but great info and I like what you said about eating right to keep up the high levels. I may give that a try in the near future. Mass Monster | ||
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Pro Bodybuilder
Posts: 526 |
Hey Johnson, if you were a sugar junky, like most Americans are, cutting out the carbs would be a major net benefit. Except for during that brief window after workout, I think I would advocate no simple carbs at all. Most people who try sugar substitutes end up preferring them after a while. My problem is with fats. Also, I LOVE potatoes and bread. I could give up real sugar no problem. zb | ||
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Cool Novice 
Posts: 39 |
http://www.t-mag.com/html/149ins.html Great article on insulin and how to tweakit. ------------------ | ||
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Elite Bodybuilder
Posts: 950 |
YEAH ZEKE, I LOVE BREAD AND POTATOS, TOO. I ALSO DIG SWEETS, BUT ONLY ALLOW MYSELF ONE OR TWO CHEAT DAYS A MONTH. I THINK STEW'S INFO IS SOLID. I'M GOING TO TRY SLIN OR THE SPORTS DRINK POST WORKOUT FOLLOWED BY SOME WPI AND SEE IF I DON'T GAIN MORE MUSCLE WITHOUT THE FAT. ------------------ NEWBIES, CLICK ON THE LINK BELOW AND GET YOUR QUESTIONS ANSWERED AT THESE FINE SITES. UPDATED WEEKLY | ||
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Elite Bodybuilder
Posts: 822 |
Good report, Stew. You are a fountain of knowledge these days - I know where you are going - just remember us when you get there. I repeat myself on this all the time...I don't care what anyone says; use steroids long enough and eventually you hit another genetic plateau - the big gains aren't there anymore. The older you get, the longer you have used, the more this is true. It gets harder to gain quality weight, harder to stay lean, harder to continuosly handle heavier weights. If you are not willing to accept this situation, then it is time to get more radical. Insulin and GH kick start the progress. The first time I used insulin, I put on 8 extra quality pounds on a cycle I had done many times. Adding in GH the next go-around got me leaner than I had been in years, while still gaining some mass. But its like the decision to use steroids the first time after reaching the limits of natural potential. Not something to just jump into, because these sustances can be hazardous if not used properly. After many times, I still screw up on carbs occasionally, and get that hypoglycemic rush that sends you running for glucose. Pair this up with Monsters Primer, and save for the day. | ||
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Olympian 
Posts: 1788 |
Excellent post. | ||
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Freak
Posts: 2009 |
Big bump for great info ------------------ Don't look back, life is too short | ||
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Amateur Bodybuilder
Posts: 108 |
Stew, Excellent post! So, you say a wpi 45 min before a workout? What about wpc? I am only asking because I use the shitty tasting Designer. I always got good gains from it and it's cheap. I am always open to suggestion (especially if it's gonna make me a BIGGER boy!!) | ||
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Elite Bodybuilder
Posts: 1083 |
WPC is ok, but it contains fat and carbs... 45 minutes is a little late for the protein. It should come 10-15 minutes after the simple carbs. The reason that I say WPI is because it is very high in glutamine and branch chained amino acids. -Stew | ||
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Mutant  
Posts: 3455 |
Great Post, worthy of an Iron Bump | ||
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Amateur Bodybuilder
Posts: 134 |
Why did I wait so long to check out this thread. Best one I've read since I've been here. Props, Stew. Here's my two cents: There's a theory that two or three of your meals should contain only protein and fat to minimize the amount of insulin put out by your pancreas each day. The thinking is this keeps your pancreas from burning out from overwork. Your other meals should consist of pro and carbs only (no fat). From what I know this seems like a good idea. Any comments/criticisms??? ------------------ | ||
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Elite Bodybuilder
Posts: 1083 |
I assure you that your pancreas is not going to "burn out" unless you are geneticly predisposed to diabetes.
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Amateur Bodybuilder
Posts: 180 |
Stew, whats your opinion on regulating carb intake, ie, 2 or 3 days following your advised high carb intake to maximize anabolism, followed by the alternative method that luv2shrug has just mentioned. Kind of like a mini abcd diet. | ||
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Moderator
Posts: 5768 |
This seems to run counter to Duchains cyclic ketogenic diets. | ||
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Elite Bodybuilder
Posts: 1083 |
Atkins diets don't work worth a crap when you are trying to add muscle... but will definately help one to shed fat (at the expense of some muscle).
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Pro Bodybuilder
Posts: 382 |
Stew that was a great post. You ought to get with George and write a book on training and diet. I for one would buy it. . | ||
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Elite Bodybuilder
Posts: 1083 |
Actually, I've been working on a book for the past year. I plan to have it finished by the end of this summer.  -Stew | ||
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Amateur Bodybuilder
Posts: 94 |
Great post STEW. I'm very happy this came around to educate me on something I have no experience with or knowledge about. I apprecate learning and is that not what we are here for in the first place. Keep up the great posts for the not too knowledgables guys such as myself. And I too wish there were more teachers on the board. | ||
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Elite Bodybuilder
Posts: 674 |
"Complex carbs are a much bigger molecule than simple sugars. They have many sugars bonded together. To turn complex carbs into glucose, they must be broken down. There is a series of steps that they must undergo to be broken down. Enzymes must be present to break each molecular bond of these polymers. All this takes a while to complete. By the time some of it is broken down into glucose, in the small intestines, some of it has already passed into the large intestine where absorption is almost completely ceased. This process allows for a slow and steady rate of glucose production that fuels the brain and muscles throughout the day without causing a release of insulin. This is very important because, as previously stated, you don�t want insulin in your body during a workout; you need its recipicle, blood sugars." The "complex carbs vs. simple carbs" argument is much more complex than a "complex is better than simple" answer. White rice, cereals, breads, potatoes, etc. are technically complex based on the polymeric chains of sugars that they are composed of, yet they ilicit insulin levels comparable or even greater than those of some simple sugars. Some simple sugars, such as lactose and fructose, actually have very low GI ratings, due to poor absorption from the intestines. Along with chemical types of sugars, the meal composition also affects the GI rating. Saturated fats tend to increase insulin levels when ingested with carbohydrates, greater than carbohydrates alone (this is why the steak and baked potato meal is not a good combo). Whey protein can ilicit a nice insulin response due to the high BCAA content (leucine is insulinogenic). One of the consistant variables in GI index tends to be fiber content of carbohydrates, which is probably more important than carbohydrate structure. The more fiber a food has the lower the GI and the lower the insulin secretion, simply due to physical hinderance of carbohydrate digestion and absorption. | ||
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Cool Novice
Posts: 49 |
Great thread Stew. You sent me part of the book you are writing and it is excellent. I have some more questions for you related to this thread. I haven't tried slin, but may try glucophage, and at the very least, would like to learn more about tweaking insulin levels with my diet. 1. I generally lift first thing in the morning. I get up, take 1-2 eca caps, and make a shake with 1 1/2 cups of skim milk, 1/2 cup oatmeal, a tablespoon of flax oil, a teaspoon (5 g.) of glutamine peptides, a scoop of penta pro protein from proteinfactory, and a scoop of penta pro mrp. The penta pro MRP contains maltodextrin, which I understand to be a complex carb that would be ok before a workout, correct? Also, since milk contains sugars, would it be best to make this shake with water instead? 2. On lifting days, I usually lift for an hour and then do cardio for a half hour. It is pretty impractical for me to lift and then to cardio at another time the same day, just takes up too much of my day with showering, driving back and forth, etc. After the cardio, I've been taking in 33 grams of dextrose mixed with 5-10 g of creatine, and 5 g. of gluatamine peptides (I've just started taking 600 mg. of alpha lipoic acid with this). Then I drive home for 15 minutes and drink a shake made with water, 60 grams of whey isolate, and 25 grams of maltodextrin. I have a solid meal about 1 1/2 hours later. Would you suggest that I change the content and/or timing of any of this? E.g. would it be better to take dextrose/creatine and/or whey isolate/maltodextrin after lifting and before cardio? ------------------ | ||
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Moderator
Posts: 6180 |
How did this post slip to the second page already?Excellent thread stew! | ||
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Elite Bodybuilder
Posts: 950 |
HEY TREVDOG, YOU SHOULD TRY THE GLUCOPHAGE. ITS WORTH IT. I STARTED IT TWO MONTHS AGO BETWEEN CYCLES AND HAVE BEEN TAKING IT EVER SINCE. I ACTUALLY NOTICED A STRENGTH INCREASE AT THE END OF THE CYCLE, SO I KNOW ITS WORTH TRYING. FROM http://www.smart-drugs.com/Metformin-WardDean.htm Metformin, to the contrary, acts by increasing the sensitivity of peripheral tissues (like muscles) to the effects of insulin. In effect, it rejuvenates this response, restoring the effects of glucose and insulin too much younger physiological levels. Although metformin is approved only for use in type II (non insulin dependant) diabetics, I use it with a great deal of success on my type 1 (insulin dependant) diabetic patients as well. SOUNDS LIKE GLUCOPHAGE MIGHT EVEN BE A GOOD THING TO TAKE WITH INSULIN. When used with insulin dependant patients, I find that they are able to dramatically reduce their doses of insulin, and more easily maintain stable levels of blood glucose. Metformin acts in a much more physiologic manner than either the sulfonylureas, or even exogensously administered (i.e. injected) insulin itself. ...I believe metformin has a profound and truly "rejuvenating effect" on glucose and insulin metabolism. Among other benefits, this results in a reduced rate of pro-aging cross linkages in collagen. Dilman (1992) lists the following benefits of phenformin, which are shared by metformin, (1) Lowers blood cholesterol, triglycerides and beta lipo-proteins ------------------ NEWBIES, CLICK ON THE LINK BELOW AND GET YOUR QUESTIONS ANSWERED AT THESE FINE SITES. UPDATED WEEKLY |
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posted April 22, 2001 11:35 PM
