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 Anabolic Discussion Board
 will i need clomid eod througout w/this cycle??
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| Author | Topic: will i need clomid eod througout w/this cycle?? | ||
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Cool Novice 
Posts: 37 |
what up bros? getting ready to order my first ever cycle, and just fine tuning it right now. just need to know if i should run clomid eod all the way through or not. let me know. this is what my cycle looks like right now with the clomid. thanks!! wk**omnadren**eq**prov**clomid     | ||
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Elite Bodybuilder 
Posts: 991 |
Never use clomid throughout a cycle.
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Amateur Bodybuilder 
Posts: 212 |
you won't NEED clomid throughout for this cycle, but it wouldn't hurt. i always feel having clomid throughout in addition to post cycle helps to bring back hpt-axis faster than using clomid post cycle only. then again you're not going to have heavy hpt-axis suppression with this cycle. | ||
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Elite Bodybuilder
Posts: 991 |
Some women can't get pregnant because they don't secrete enough LH and FSH at the right time during the cycle and, as a result, they don't ovulate. For these women, the first drug doctors often prescribe is clomiphene citrate (Clomid, Serophene). This synthetic drug stimulates the hypothalamus to release more GnRH, which then prompts the pituitary to release more LH and FSH, and thus increases the stimulation of the ovary to begin to produce a mature egg. Structurally like estrogen, clomiphene binds to the sites in the brain where estrogen normally attaches, called estrogen receptors. Once these receptor sites are filled up with clomiphene, they can't bind with natural estrogen circulating in the blood and they are fooled into thinking that the amount of estrogen in the blood is too low. In response, the hypothalamus releases more GnRH, causing the pituitary to pump out more FSH, which then causes a follicle to grow to produce more estrogen and start maturing an egg to prepare for ovulation. Typically, a woman taking clomiphene produces double or triple the amount of estrogen in that cycle compared to pretreatment cycles. Clomiphene is a very safe medication with relatively few contraindications. Preexisting liver disease is one contraindication since clomiphene is metabolized by the liver. THERE IS A FEEDBACK LOOP THAT PRODUCES BOTH TESTOSTERONE AND SEMEN. SEMEN I BELIEVE IS MADE IN THE SERTOLI CELLS OF THE TESTES, TESTOSTERONE IN THE LEYDIG? CELLS. (I'M GUESSING ON THAT ONE.) BOTH ARE PRODUCED UPON STIMULATION OF THE SO-CALLED FSH AND LH. FSH - FOLLICLE STIMULATING HORMONE CLOMID STIMULATES THE PRODUCTION OF FSH AND LH WHICH IN TURN GENERATES MORE TESTOSTERONE AND SEMEN PRODUCTION IN MEN. (IN WOMEN IT STIMULATES THE PRODUCTION OF EGGS THUS CLOMID'S PRIMARY USE AS A FERTILITY DRUG.) AS WE AGE WE PRODUCE LESS TESTOSTERONE. SOME ADVOCATE A TESTOSTERONE PATCH ETC AS A REMEDY. I PREFER THE PRECURSOR ROUTE USING THE CLOMID. I BELIEVE THIS IS PREFERABLE TO THE UNFETTERED INTRODUCTION OF TESTOSTERONE INTO YOUR SYSTEM AS THAT CAN TRIGGER THE NEGATIVE FEEDBACK LOOP WHICH WILL SHUT OFF YOUR OWN NATURAL TESTOSTERONE PRODUCTION. THIS HAPPENS WHEN YOUR BODY SENSES THERE IS TOO MUCH TESTOSTERONE FLOATING AROUND IN THE BLOODSTREAM. USING A PRECURSOR SUCH AS CLOMID IS FAR LESS LIKELY TO TRIP THE SWITCH WHICH SHUTS OFF TESTOSTERONE. HCG is best used during a long cycle as a means of stimulating natural Testosterone production, rather than at the end of a cycle. The reason for this is that the surge of T from HCG will trigger more negative feedback, which is exactly what you don't want at the end of a cycle when you should be trying to coax natural T production to come back online. Clomiphene Citrate (Clomid) is more effective than HCG at the end of a cycle. It blocks estrogens at the hypothalamus. This reduces the negative feedback from high estrogen levels and allows for a resumption of natural T production. Clomid will not block the feedback that results from high androgen levels but androgen based feedback dominates only when T levels are very high, such as during a cycle when HCG is the better choice.
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posted April 19, 2001 09:56 PM