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 Anabolic Discussion Board
 Do Clomid & Nolvadex Compete For Receptors?
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| Author | Topic: Do Clomid & Nolvadex Compete For Receptors? | ||
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Amateur Bodybuilder 
Posts: 58 |
I've started my post cycle clomid, and I'm wondering if nolvadex will hurt or help. I know they both attach to estrogen receptors, so is it possible that nolvadex will compete with clomid in the hypothalamus reducing it's LH increasing properties? I took Nolvadex throughout my cycle, (cutting cycle, 10mg EOD.) so should I continue with it or stop? Today is my first day of clomid, doing the 300mg the first day, 100mg there after and so on.     | ||
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Amateur Bodybuilder
Posts: 58 |
Anyone...? | ||
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Amateur Bodybuilder
Posts: 162 |
Great question. I looked up clomid in the PDR, and it says it has both estrogenic and anti-estrogenic properties. It also lists gyno as a potential side effect in males, but it could be a really small percentage without a real cause and effect relationship. Basically, I'm saying that I have no friggin' idea as to the answer to your question. However, I'm hoping that someone can tell us something. | ||
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Cool Novice 
Posts: 14 |
YES I AM VERY CURIOUS.....SOMEONE | ||
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Amateur Bodybuilder
Posts: 58 |
I should probably add that I'm not concerned with gyno at this point. If I was going to get it, I would have by now. I am concerned with getting my natrual test level as high as possible. So, will continuing nolvadex help or hurt this process? | ||
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Amateur Bodybuilder
Posts: 162 |
bump | ||
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Pro Bodybuilder 
Posts: 381 |
Clomid is an estrogen receptor antagonist. This means it works by filling an estrogen receptor without activating it. The only way to interfere with this behavior is to be an estrogen receptor agonist or fill the receptor and activate it. It is my understanding that nolvadex is an antagonist as well. If so, no problem. Anyone else? | ||
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Moderator 
Posts: 7478 |
No there is no problem. Even if they did compete (which they don't) you would be better off no matter what. ------------------ Great Information on Injections and Syringes | ||
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Elite Bodybuilder 
Posts: 878 |
Clomid has selective binding affinities to ER in the hypothalamus, but Nolvadex is non-selective. -Stew | ||
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Amateur Bodybuilder
Posts: 74 |
CLOMID DOES THE SAME THING AS HCG AND IT BINDS ESTROGEN RECEPTORS-NOLVADEX JUST PLAIN SUCKS-WOULDN'T USE IT IF I GOT IT FOR FREE. | ||
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Moderator
Posts: 6026 |
Clomid does NOT do the same thing as HCG.Clomid blocks estrogen's signal from the hypothalamus & pituitary,causing them to produce their signified hormones and re-initializing the T production process.HCG "mimics"leutenizing hormone in the testes,causing them to produce testosterone.It does nothing to get the hypothalamus or pituitary back in line.... |
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posted April 07, 2001 07:24 PM