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  Anadrol as an antiestrogen?

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Author Topic:   Anadrol as an antiestrogen?
Stew Meat

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From:Louisiana
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posted April 06, 2001 01:05 PM

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Ok... Here's one for MeanOne... wherever he is...

"While oxymetholone does not convert to estrogen because of its saturated a-ring, gynecomastia (feminized breasts) has been seen in males using oxymetholone, but this generally only occurs if it is combined with growth hormone, or testosterone, either of which can cause gynecomastia by themselves. Used alone, we have seen oxymetholone cause gynecomastia to shrink quickly, probably because oxymetholone can exert inhibitory, anti-estrogenic effects on hormone-responsive breast tissue."

This was written by a Nelson Vergel.
As I understand it, anadrol has a progestrogenic aromatization. Could progesterone block estrodiol?

Where ya at Macro...


-Stew

[This message has been edited by Stew Meat (edited April 06, 2001).]


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OAK

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posted April 06, 2001 01:08 PM

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I just got the new muscle mag and in the uncensored section, in an interview with the guys from Anabolic 2000, they were talking about the same thing.

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"That which does not kill me will make me stronger"

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HUCKLEBERRY FINNaplex

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posted April 06, 2001 01:11 PM

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Eeesh.If that were the case,then I would say that deca(another progestin based anabolic)would do the same,which we all know it doesn't.The lowering of estradiol might have some validity,but to say it REDUCES gyno is a little far-fetched IMHO.I have had buddy's that have gotten NASTY gyno on anadrol-only cycles,so I know that it's capable of activating receptors in Mammary tissue.Interesting theory,nonetheless...

[This message has been edited by HUCKLEBERRY FINNaplex (edited April 06, 2001).]


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Big Johnson

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posted April 06, 2001 01:23 PM

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OKAY BROS, I'M NOT AS KNOWLEDGABLE AS HUCK OR STEW, BUT I WAS UNDER THE IMPRESSION THAT ESTROGEN DOES NOT CAUSE GYNO. YET, I SAW THIS THE OTHER DAY WHILE DOING SOME SURFING:

"Gynecomastia frequently develops and occasionally persists in patients being treated for hypogonadism." (FROM http://www.powerpak.com/CE/Androgen/lesson.cfm)

THE PATIENTS IN THIS CASE ARE MALES BEING TREATED WITH TEST. WTF? I THOUGH ONLY DECCA, FINA, AND ANADROL CAUSED GYNO BECAUSE OF PROGESTERONIC SIMULATION. COULD ESTROGEN CAUSE GYNO AS WELL?

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OAK

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posted April 06, 2001 01:23 PM

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Here's another. Site injections of gh to reduce fat behing the nipple. What do you guys think about that one. They say gh cause localized fat lose. Another Muscle mag tid bit.

------------------
" I used to be lawnsaver!"

"That which does not kill me will make me stronger"

"Catch a man a fish and he eats for a day. Teach a man to fish and he eats for a lifetime."


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OAK

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posted April 06, 2001 01:26 PM

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Estrogen is the biggest developer of gyno. Estrogen is what forms womens breast, estrogen is what transvestites use to increase their breasts. That is why we use nolvadex and arimidex to combat gyno.

If I miss read your post and you were saying something else, I am sorry.

------------------
" I used to be lawnsaver!"

"That which does not kill me will make me stronger"

"Catch a man a fish and he eats for a day. Teach a man to fish and he eats for a lifetime."


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Big Johnson

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posted April 06, 2001 01:33 PM

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WHAT DOES PROGESTERONE DO THEN? WHY IS IT SO MANY GUYS TAKE WINNY FOR ITS ANTI-PROGESTERONIC QUALITIES TO COMBAT GYNO?

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OAK

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posted April 06, 2001 01:37 PM

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the conversion of Progest. can give you gyno from another aveune. So we have 2 enemies!

------------------
" I used to be lawnsaver!"

"That which does not kill me will make me stronger"

"Catch a man a fish and he eats for a day. Teach a man to fish and he eats for a lifetime."


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HUCKLEBERRY FINNaplex

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posted April 06, 2001 01:37 PM

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Big J-Both estrogen and progesterone are primary female hormones.An abundance of either one is capable of activating receptors in breast tissue of males with sensitivity to these hormones....


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Stew Meat

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posted April 06, 2001 01:38 PM

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Progesterone is estrogen.
Many people don't realize that.
Progesterone is different from estrodiol, but both are female hormones and both can cause gyno.


-Stew

[This message has been edited by Stew Meat (edited April 08, 2001).]


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Stew Meat

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posted April 06, 2001 01:41 PM

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Huck, we posted at the same time again

On another note, people use Winny as an anti-progesterone when taking deca, fina, and anadrol. One does not need to take an antiestrogen with Winny as Winny will not aromitise into estrodiol like testosterone, dbol, and EQ.


-Stew


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HUCKLEBERRY FINNaplex

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posted April 06, 2001 01:43 PM

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LOL.Great minds think alike


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Big Johnson

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posted April 06, 2001 01:54 PM

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SO THEN, AN ANADROL/WINNY STACK MIGHT BE ONE HELL OF A LIVER FUCK, BUT WON'T GIVE YOU GYNO AND MAY ACTUALLY SHRINK EXISTING AND HERE I ALWAYS THOUGHT ANADROL WAS POISON.

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Jafar

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posted April 06, 2001 02:11 PM

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quote:
Originally posted by HUCKLEBERRY FINNaplex:
Eeesh.If that were the case,then I would say that deca(another progestin based anabolic)would do the same,which we all know it doesn't.The lowering of estradiol might have some validity,but to say it REDUCES gyno is a little far-fetched IMHO.I have had buddy's that have gotten NASTY gyno on anadrol-only cycles,so I know that it's capable of activating receptors in Mammary tissue.Interesting theory,nonetheless...

[This message has been edited by HUCKLEBERRY FINNaplex (edited April 06, 2001).]


I too was under the impression that A-50 could CAUSE gyno all by itself. I just finished a cutting cycle using anadrol and test enanthate (farily low doses of each, short duration, while dieting heavily) and used nolvadex 10mg EOD because of that fear. Was this not necessary?


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SMS

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posted April 06, 2001 02:23 PM

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The nolva would have covered the test, but not the a-50. Personally, I would never do drol without winny.


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MassKing

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posted April 06, 2001 02:29 PM

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gyno is caused by having too much estrogen or progesterone in the body. how do you get this in your body? your body produces it to counteract all the testosterone in your body to creat balance. the breast are estrogen sensitive so the receptors around your breast fill with these hormones causing growth in these tissues. almost all AS will cause your body to produce these hormones. some steroids will balance each other out so as not to effect these tissues as much, for example abombs with winstrol.


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Stew Meat

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posted April 06, 2001 02:34 PM

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Mass, human males can not produce estrogen.


-Stew


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Big Johnson

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posted April 06, 2001 02:37 PM

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TEST AROMATIZES INTO ESTROGEN, MASS. I DON'T THINK MEN CAN PRODUCE ESTROGEN UNLESS THEY HAVE OVARIES

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Verbal Gorilla

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posted April 06, 2001 02:50 PM

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Progestrone is Estrogen! No....Progestrone is a precursor for Estrogen though...

Take a look at what Hormone replacement theary is in women....every hear of Estrogen domanince...and what is used to combat this? Progestrone! Most of estrogen�s undesirable side effects are effectively prevented by progesterone...in women


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Verbal Gorilla

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posted April 06, 2001 02:52 PM

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Now you are saying human males cannot produce Estrogen!!! What! You are a smart guy, but you sure don't know your hormones...Estrogen is produced by the adreanal glands by both sexes and by the testis in males...


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Big Johnson

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posted April 06, 2001 03:03 PM

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I DIDN'T KNOW THAT GORILLA. I THOUGHT TESTES PRODUCED TEST AND OVARIES PRODUCED ESTROGEN, EXCLUSIVELY. I ALSO THOUGHT THAT THE MALE BODY BALANCED ITS TEST PRODUCTION BY THE AMOUNT OF ESTROGEN PRESENT, BUT I GUESS THAT DOESN'T MAKE TOO MUCH SENSE BECAUSE THE RESULT WOULD BE TEST AROMATIZING INTO EVEN MORE ESTROGEN, WHICH WOULD CAUSE EVEN MORE TEST TO BE PRODUCED AND MORE AROMATIZED INOT ESTROGEN. LOOK, I WAS A BIO MAJOR FOR AWHILE BUT THIS SHIT IS STRATING TO CONFUSE THE HELL OUTTA ME!

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MassKing

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posted April 06, 2001 04:44 PM

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you guys know what i meant. i know we dont produce progesterone.


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Stew Meat

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posted April 06, 2001 04:55 PM

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No, males can not produce estrogen in the adrenal gland. However, females can produce testosterone in the ADRENAL CORTEX.

Progesterone is not a precursor for estrodiol.

Estrogen is produced in the ovaries not the adrenal gland.

-Stew

[This message has been edited by Stew Meat (edited April 08, 2001).]


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Verbal Gorilla

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posted April 06, 2001 07:52 PM

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Stew....you are absolutly killing me...

The 3 main sex hormones are estrogen, progestrone, and androgen....testosterone is an androgen....Estrogen, like androgen, is actually the name of a group of hormones, Estradiol(E2), Estrone(E1), Estriol(E3). Progestrone is indeed a precursor to Estrogen as well as testosterone...

And you are crazy if you say that males don't produce Estrogen and progestrone...How could exongerous test result in increased estrogen levels? Magic? Maybe Animals secert meeting of all steriod manufactures, who are responsible for the sting in prop, also decided to sneak estrogen in all of there products....same goes for deca and progestrone...


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Big Johnson

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posted April 06, 2001 08:40 PM

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THAT'S IT, I'M DIGGING OUT MY BIO TEXT BOOK...

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Stew Meat

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posted April 06, 2001 08:43 PM

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quote:
Originally posted by Verbal Gorilla:
Stew....you are absolutly killing me...


you are crazy if you say that males don't produce Estrogen and progestrone...How could exongerous test result in increased estrogen levels? Magic? Maybe Animals secert meeting of all steriod manufactures, who are responsible for the sting in prop, also decided to sneak estrogen in all of there products....same goes for deca and progestrone...


I'm not going to sit here and argue about it, Fonz, I mean Gorilla...
I don't even know why I'm going to bother with this because you are one of those who know more than the one's who devote their lives to their respected feilds and your "theories" are above the boundries of being proven wrong by scientific research, but here is a direct quote from "Physiological Applications" by Dr. James W. Kalat, North Caroina State Univ. Seventh Edition, 2001...
"Sex hormones can be divided into two major categories, female hormones (estrogens) and male hormones (androgens). Although both classes of hormones exist in males and females, the estrogen to testosterone ratio in females is 10:1 and in males, the ratio is 1:10... the female ovaries are incapable of producing testosterone as are testicles incapable of producing estrogen. The adrenal cortex is responsible for the excretion of testosterone in females where the only mechanism of estrogen production in males lies in the ability of aromatase enzymes to convert a percentage of testosterone into estrogen."


Magic!

-Stew

[This message has been edited by Stew Meat (edited April 06, 2001).]


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Big Johnson

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posted April 06, 2001 08:52 PM

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quote:
Men have about half the amount of estrogen as women - the male hormone testosterone is converted into estrogen in the brain - but their supply never completely diminishes.

FROM http://www.sfn.org/briefings/estrogen.html

BETTER RETHINK YOUR HORMONES, GORILLA

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Big Johnson

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posted April 08, 2001 04:23 PM

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BUMP

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JohnyJuice

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posted April 08, 2001 04:29 PM

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anadrol as an anti estrogen? HAHAHAHAHAHAAHAAAHAHAAAAAHAAHA!


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Big Johnson

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posted April 08, 2001 04:54 PM

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SO, WHEN YOUR BODY HAS TOO MUCH TEST, ENZYMES THAT BREAK IT DOWN INTO ESTROGEN ARE RELEASED. TOO BAD NO ONES COME UP WITH A WAY TO BLOCK/DESTROY THOSE. OR HAVE THEY?

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HUCKLEBERRY FINNaplex

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posted April 08, 2001 05:00 PM

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Yes.That is precisely what arimidex,and to a lesser degree Cytadren and proviron do.They stop aromitase at it's root of formation....


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Big Johnson

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posted April 08, 2001 06:28 PM

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HEY HUCK, DO YOU THINK CLOMID, WITH ITS INFLUENCE ON THE HYPOTHALAMUS, DOES THE SAME? STOPS THE RELEASE OF AROMATASE ENZYMES?

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HUCKLEBERRY FINNaplex

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posted April 08, 2001 06:35 PM

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No,it is a selective estrogen receptor modulator.Its activities combat estrogen that's already in free-circulation.It does not prevent its developement,it only blocks it from attaching to certain receptors by occupying those receptors in an idle state(not activating them).


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Big Johnson

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posted April 08, 2001 06:39 PM

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THANKS FOR INFO, HUCK. LOOKS LIKE ARIMIDEX DURING A CYCLE OF HEAVY TEST IS ESSENTIAL IF YOU DON'T WANT ESTROGEN SIDES.

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HUCKLEBERRY FINNaplex

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posted April 08, 2001 06:40 PM

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True,nothing else compares.


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