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 DOES YOUR BODY DEVELOPS A TOLERANCE TO JUICE!
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| Author | Topic: DOES YOUR BODY DEVELOPS A TOLERANCE TO JUICE! |
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JUICESEEKER Amateur Bodybuilder (Total posts: 64) |
posted April 13, 2000 04:18 PM
  
I AM GETTING PREPARED TO DO A FIRST CYCLE AND IT WAS GOING TO BE 400MG A WEEK OF DECA AND 200MG A WEEK OF PRIMO FOR 10WKS. AND MY QUESTION IS.......... IF I DO A SECOND CYCLE, WILL I HAVE TO DO SOMETHING STRONGER LIKE TEST AT A HIGH DOSAGE TO GET THE SAME RESULTS, OR I CAN USE PRIMO AND DECA AGAIN AND STILL GET THE SAME RESULTS. SOMBODY PLEASE RESPOND. THANKS! IP: Logged |
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JUICESEEKER Amateur Bodybuilder (Total posts: 64) |
posted April 13, 2000 05:02 PM
bump! fellas i need an answer on this quesion. IP: Logged |
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musclegear Amateur Bodybuilder (Total posts: 20) |
posted April 13, 2000 05:07 PM
Yes, your receptors can get "dirty" if you stay on anabolics too long, that is why most people cycle them. For a first cycle I would definitely throw in 250mg of Sustanon per week, the primo and decca are great steroids, but neither are testosterones, which you should throw in if you want to put on some quality MASS. Plus if you take sustanon, it's a blend of four tests so you'll be hitting 4 receptor sites right there alone. BTW, if this is a first cycle you could get away with 200mg of Decca per week instead of 400mg. IP: Logged |
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LittleSavage34 Pro Bodybuilder (Total posts: 231) |
posted April 13, 2000 06:23 PM
I don't think the body builds up a tolerance to steroids. Your receptors will become saturated, therefore, you won't see the gains you seek. Most people cycle, and that gives the receptors a chance to clean up. When you hit the next cycle, you will be set. I take at least 8 weeks off between cycles. Some people only do two cycles a year. It's just your personal preference and your pocketbook. For your next cycle, try using Sust/Deca/Dbol. ------------------ IP: Logged |
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coolhandluke Pro Bodybuilder (Total posts: 470) |
posted April 13, 2000 06:35 PM
musclegear: 4 receptor sites????? ok, so the body has different receptors for different esters????? I don't think so. IP: Logged |
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tri~zilla Pro Bodybuilder (Total posts: 177) |
posted April 13, 2000 07:24 PM
first things first. if i've read the vets right, 250 mgs of sust only shuts down your natural levels. take that into consideration. second. sust isn't made up of different testostrones. it's just testostrones in different esters causing the test to release last but not least, there are different opinions about certain AS's clinging to only certain receptor sites. p.s i'm ready to be flamed by the vets tri ------------------ IP: Logged |
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musclegear Amateur Bodybuilder (Total posts: 20) |
posted April 13, 2000 08:41 PM
coolhandluke: So what you're saying is there's only one receptor site for all testosterones? I guess everything I've read and been told by the supposed guru's on anabolics.com is a bunch of hogwash, Enlighten me. IP: Logged |
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E2 Moderator (Total posts: 2354) |
posted April 13, 2000 10:02 PM
yup your anabolics.com guru's lead you downt he wrong path, the esters just determine how long the molecule says in suspension in your body until it is able to become active. read this actually everyone should read it, i'm gonna post it. IP: Logged |
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ruffy Pro Bodybuilder (Total posts: 139) |
posted April 13, 2000 11:08 PM
E2, that is a good article, very educational. When I looked at a steroid name in the past, I had no idea that the name is comprised of the ester(deca-noate) and the hormone(durabolin). Thanks IP: Logged |
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E2 Moderator (Total posts: 2354) |
posted April 14, 2000 12:01 AM
Deca durabolin is a brand name like ford it's nandrolone decanoate, the chemical name. IP: Logged |
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Joseph_stalin Pro Bodybuilder (Total posts: 530) |
posted April 14, 2000 03:28 AM
if you increase your metabolism that supposedly removes the dead steroids from their androgen receptors. so if you saturate your self you might want to do a dnp/cytomel cycle to increase metabolism. which will give you more receptors. after you reach your peak on that, ie even with all your receptors open you still wont grow you will have to resort to either insulin or GH. IP: Logged |
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cockdezl Amateur Bodybuilder (Total posts: 16) |
posted April 16, 2000 01:40 PM
The misinformation on this topic is frightening. As COOLHANDLUKE stated, there is essentially only one receptor: the androgen receptor, which we will call here out the AR. (NOTE: there is evidence for modified AR's that have varying capacity to bind certain steroids better, but this is the exception not the rule.) When a steroid enters the cell, it binds the AR in the cytoplasm, and forms a steroid/receptor complex. This complex then diffuses across the nuclear membrane, binds the DNA and initiates transcription of genes. This is why the concept of "dirty" receptors or "cleaning" the receptors is false. As a steroid/receptor complex is formed, it is removed from the cytoplasm, and another AR is replaced in the cytoplasm. If the drug levels are high enough then all the receptors can be filled, but new ones are constantly formed. There is controversy as to whether this is downregulated or upregulated with increased drug use. Another poorly understood concept is that of drug/receptor affinity. Some steroids have very strong binding affinities to the AR, meaning that they hold onto the AR very tightly, while others do not. A drug with a high AR affinity is effective at a lower dose than one with a weaker affinity. Example: trenbolone has a greater affinity for the AR, than test, thus it produces similar responses at lower doses than testosterone. Just because a steroid has a weak affinity to the AR, does not mean that that drug is weak. New research has shown that some effects of steroids are not mediated through the AR. So it may be useful to gain the benefits of two or more drugs that have different mechanisms of action, one mediated through the AR and one with extra-AR effects. Bill Roberts has written more extensively on all of these topics and should be read by anyone interested. He has articles at MESOMORPHOSIS.com and on old misc.fitness.weights posts that are available at Deja.com. So when one stops a cycle, the main goal is to allow for recovery of the endogenous testosterone production and for the body to normalize all the processes, that had been previously stimulated; i.e. protein translation, AR modulation, enzyme upregulation, etc. IP: Logged |
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tri~zilla Pro Bodybuilder (Total posts: 177) |
posted April 16, 2000 01:50 PM
that was some good info, but what does the name mean ? cockdezl? ------------------ IP: Logged |
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Rich1 Pro Bodybuilder (Total posts: 102) |
posted April 16, 2000 03:10 PM
Excellent home work cockdzel, very well put, this shit about different receptors is crap,if this were true we'd have different receptors for deca, winny, d-bol etc...there can only be one....great stuff. I knew that crap at the other board was bull...Keep up the good work! IP: Logged |
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susthead Amateur Bodybuilder (Total posts: 71) |
posted April 16, 2000 05:24 PM
personaly i think that the liver gets very efficent and learns how to break the drugs down the longer your own so they loose some effectiveness emm dont stay on more than 12 weeks start at your top dose and tapper down never tapper up waste of time... IP: Logged |
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