posted April 11, 2000 01:45 AM            

What are dinitrophenols?
(Pronounced die ni'tro fe' nolz)

Dinitrophenols are a class of manufactured chemicals that do not occur naturally in the environment. There are six different dinitrophenols.

The most commercially important dinitrophenol, 2,4-dinitrophenol (DNP), is a yellow solid with no smell. It is used in making dyes, wood preservatives, explosives, insect control substances, and other chemicals, and as a photographic developer.

DNP DOES SMELL-VERY STRONG- KIND OF LIKE CHERRY WOOD

It was used in diet pills in the 1930s but was banned for this use in 1938. It may be sold under several trade names, including Caswell No. 392, Sulfo Black B, and Nitro Kleenup. Use of trade names is for identification only and does not imply endorsement by the Agency for Toxic Substances and Disease Registry, the Public Health Service, or the U.S. Department of Health and Human Services.

What happens to dinitrophenols when they enter the environment?

DNP enters the air, water, and soil during its manufacture and use.
It may be formed from reaction of other chemicals in the air.
DNP may also enter the environment through landfill and storage tank leaks, or accidental spills during manufacture or transport.
It dissolves slightly in water, and does not easily evaporate to air.
It can be broken down slowly in water and soil by small organisms or by reacting with other chemicals.
DNP sticks to particles in water, which will cause it to eventually settle to the bottom sediment.
DNP also sticks to some types of soil particles, which may prevent it from moving very deep into the soil with rainwater.
DNP probably does not build up significantly in fish.
How might I be exposed to dinitrophenols?

Breathing contaminated workplace air where it is manufactured or used.
Breathing contaminated air from DNP-containing waste sites, waste incineration, or automobile exhaust.
Touching contaminated soil or water near DNP-containing waste sites.
Ingesting contaminated soil or water near DNP-containing waste sites.

DONT FORGET ENCAPUSLATING AND CONSUMING IT

How can dinitrophenols affect my health?

Most of the information on the health effects of dinitrophenols comes from old studies of patients who were prescribed diet pills containing dinitrophenol before it was banned. THIS IS MISLEADING, BECAUSE NO ONE DIED DURING THE DIET PILL ERA- MOST OF THE FATALITY STUDIES HAVE BEEN DONE IN ANIMALS AND ANECDOTAL RESEARCH ON THE WORKERS IN FRENCH MUNITIONS WHO WERE EXPOSED TO HUGE AMOUNTS OF DNP DURING WWI.

Deaths have occurred in people who ingested 3-46 milligrams of dinitrophenols per kilogram of body weight per day (3-46 mg/kg/day) for short periods, or 1-4 mg/kg/day for long periods. WHILE THIS MAY BE TRUE THEY DIED FROM DEHYDRATION, HYPERTHERMIA, AND STARVATION/EXTREME LOW BLOOD SUGAR, ETC..- ALL OF WHICH CAN BE AVOIDED WITH PROPER NUTRITION, SUPPLEMENTS AND EATING- DONT FORGET THOSE CARBS. Also, people who breathed air containing 40 mg dinitrophenols per cubic meter of air (40 mg/m3) for long periods have died.

The amount of dinitrophenols ingested that causes harmful effects varies among people. Increased basal metabolic rate (the rate that you use energy at complete rest)- MAKES YOU LOSE FAT, increased sweating- DEHYDRATES YOU- WHY YOU TAKE GLYCEROL AND 2 GALLONS OF WATER MIN., a feeling of warmth, weight loss-WHY MOST PEOPLE TAKE IT, and increased heart rate-THIS IS NOT TRUE-EXCEPT IN CASES WHERE LOW BLOOD SUGAR RESULTS IN THE RELEASE OF GLUCAGON,ETC.., breathing rate-INCREASED RESPIRATION IS A NORMAL FUNCTION OF INCREASED METABOLISM, and body temperature have been observed in people who swallowed as little as 1 mg/kg/day or as much as 46 mg/kg/day for short or long periods of time.

Ingesting 2-4 mg/kg/day DNP for short or long periods has caused cataracts in some people-ONE PERSON-THEY HAVE ONE ANECDOTAL CASE- WHICH REMARKABLY, WHEN COMPARED TO THE DNP INGESTING POPULATION, IS THE SAME AS AMONG THE GENERAL POPULATION-STILL WE TAKE EXTRA ANTIOXIDENTS- JUST IN CASE, while ingesting 1-4 mg/kg/day for short or long periods has caused skin rashes and decreases in white blood cells.-I HAVE SEEN NO RESEARCH THAT POINTS THIS OUT BUT SKIN RASHES WERE PROBABLY DUE TO LESS FATTY ACIDS FOR SKIN MAINTANANCE AND SOME ALLERGIC REACTIONS

How likely are dinitrophenols to cause cancer? NO-NO-NO-

The Department of Health and Human Services (DHHS), the International Agency for Research on Cancer (IARC), and the EPA have not classified dinitrophenols for carcinogenicity. FOR GOOD REASON DNP HAS BEEN SHOWN TO NOT BE CARCINOGENIC

There are no studies available in people or animals on the carcinogenic effects of dinitrophenols.
WELL AREN'T WE LITTLE LIARS- THERE HAVE BEEN CANCER STUDIES IN ANIMALS 6 MONTHS AT HIGH EXPOSURE LEVELS IN MICE- NO CARCINOMAS

Is there a medical test to show whether I've been exposed to dinitrophenols?

Tests are available that measure the amount of DNPs or their breakdown products in blood, urine, and samples of tissue from the body. DNP MAGICALLY MAKES YOUR BODILY FLUIDS A PRETTY YELLOW OR GREEN DEPENDING ON THE NATURAL COLOR OF THE FLUID OR EXCRETION. IT IS VERY AMUSING. However, these tests may require special equipment and may not be available in your doctor's office.

Has the federal government made recommendations to protect human health?

The EPA recommends that not more than 70 parts of dinitrophenols per billion parts of water (70 ppb) be present in lakes or streams used for swimming.

The EPA lists DNPs as hazardous air pollutants (HAP) under the Clean Air Act. The EPA also requires that discharges or spills into the environment of 10 pounds or more be reported.

SOME EXTRA POINTS DNP IS ANTI PROTEOLYTIC- MUSCLE SPARING-

DNP IS STILL DANGEROUS IF TAKEN INCORRECTLY AND/OR WITHOUT THE PROPER PREPARATIONS. ITS USE IS NOT AN UNDERTAKING THAT SHOULD BE ENTERED INTO WITHOUT CONSIDERABLE KNOWLEDGE AND RESEARCH- KNOWLEDGE IS POWER.

BTW- DNP IS NOT FOR PREGNANT WOMEN- DNP IS A TERATOGEN- YOU SHOULD ALSO NOT TAKE IT AND HAVE SEX WITH YOUR PREGNANT WIFE OR GIRLFRIEND- EVEN SLEEPING IN THE SAME BED COULD BE HARMFUL BECAUSE YOU BREATH AND SWEAT OUT DNP ALL THE TIME- SO BASICALLY DONT TAKE IT IF YOUR SIGNIFIGANT OTHER IS PREGNANT

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MP

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MP

posted April 11, 2000 12:28 PM            

I am lazy so I will reply within your message: milkman I am well aware that phenols CAN be mutagenic inducers of Carcinomas, however the animal studies that I have seen DO NOT show that- if you have studies that show DNP is a carcinogen in Animals by all means post it- BTW- my comments were meant to be pro DNP, I never claimed to be objective.
MP

posted April 11, 2000 01:58 PM            

8^)

One question though, how long after the end of a DNP cycle should you continue taking the LARGE doses of antioxidants? I've been working under the assumption that the vast majority of DNP will have left the system 7 days after the last dose (half-life ~36hrs) so they should be continued at least a weak after conclusion. Correct???

I'm 5 days of of DNP now and still O.D.ing on those anti-O's

Puc

posted April 12, 2000 03:17 AM            

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MP

posted April 12, 2000 10:20 PM            

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MP