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  George Spellwin's ELITE FITNESS Discussion Boards
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  DNP-the governments toxicity opinions-MACRO'S COMMENTS

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Author Topic:   DNP-the governments toxicity opinions-MACRO'S COMMENTS
macrophage69alpha
Moderator
(Total posts: 1194)
posted April 05, 2000 08:56 PM     Click Here to See the Profile for macrophage69alpha   Click Here to Email macrophage69alpha     Edit/Delete Message
some how this magical work got lost
so here it is again

you will find my comments in ALL CAPS

What are dinitrophenols?
(Pronounced die ni'tro fe' nolz)

Dinitrophenols are a class of manufactured chemicals that do not occur naturally in the environment. There are six different dinitrophenols.

The most commercially important dinitrophenol, 2,4-dinitrophenol (DNP), is a yellow solid with no smell. It is used in making dyes, wood preservatives, explosives, insect control substances, and other chemicals, and as a photographic developer.

DNP DOES SMELL-VERY STRONG- KIND OF LIKE CHERRY WOOD

It was used in diet pills in the 1930s but was banned for this use in 1938. It may be sold under several trade names, including Caswell No. 392, Sulfo Black B, and Nitro Kleenup. Use of trade names is for identification only and does not imply endorsement by the Agency for Toxic Substances and Disease Registry, the Public Health Service, or the U.S. Department of Health and Human Services.

What happens to dinitrophenols when they enter the environment?

DNP enters the air, water, and soil during its manufacture and use.
It may be formed from reaction of other chemicals in the air.
DNP may also enter the environment through landfill and storage tank leaks, or accidental spills during manufacture or transport.
It dissolves slightly in water, and does not easily evaporate to air.
It can be broken down slowly in water and soil by small organisms or by reacting with other chemicals.
DNP sticks to particles in water, which will cause it to eventually settle to the bottom sediment.
DNP also sticks to some types of soil particles, which may prevent it from moving very deep into the soil with rainwater.
DNP probably does not build up significantly in fish.
How might I be exposed to dinitrophenols?

Breathing contaminated workplace air where it is manufactured or used.
Breathing contaminated air from DNP-containing waste sites, waste incineration, or automobile exhaust.
Touching contaminated soil or water near DNP-containing waste sites.
Ingesting contaminated soil or water near DNP-containing waste sites.

DONT FORGET ENCAPUSLATING AND CONSUMING IT


How can dinitrophenols affect my health?

Most of the information on the health effects of dinitrophenols comes from old studies of patients who were prescribed diet pills containing dinitrophenol before it was banned.

Deaths have occurred in people who ingested 3-46 milligrams of dinitrophenols per kilogram of body weight per day (3-46 mg/kg/day) for short periods, or 1-4 mg/kg/day for long periods. WHILE THIS MAY BE TRUE THEY DIED FROM DEHYDRATION, HYPERTHERMIA, AND STARVATION/EXTREME LOW BLOOD SUGAR, ETC..- ALL OF WHICH CAN BE AVOIDED WITH PROPER NUTRITION, SUPPLEMENTS AND EATING- DONT FORGET THOSE CARBS. Also, people who breathed air containing 40 mg dinitrophenols per cubic meter of air (40 mg/m3) for long periods have died.

The amount of dinitrophenols ingested that causes harmful effects varies among people. Increased basal metabolic rate (the rate that you use energy at complete rest)- MAKES YOU LOSE FAT, increased sweating- DEHYDRATES YOU- WHY YOU TAKE GLYCEROL AND 2 GALLONS OF WATER MIN., a feeling of warmth, weight loss-WHY MOST PEOPLE TAKE IT, and increased heart rate-THIS IS NOT TRUE-EXCEPT IN CASES WHERE LOW BLOOD SUGAR RESULTS IN THE RELEASE OF GLUCAGON,ETC.., breathing rate-INCREASED RESPIRATION IS A NORMAL FUNCTION OF INCREASED METABOLISM, and body temperature have been observed in people who swallowed as little as 1 mg/kg/day or as much as 46 mg/kg/day for short or long periods of time.

Ingesting 2-4 mg/kg/day DNP for short or long periods has caused cataracts in some people-ONE PERSON-THEY HAVE ONE ANECDOTAL CASE- WHICH REMARKABLY, WHEN COMPARED TO THE DNP INGESTING POPULATION, IS THE SAME AS AMONG THE GENERAL POPULATION-STILL WE TAKE EXTRA ANTIOXIDENTS- JUST IN CASE, while ingesting 1-4 mg/kg/day for short or long periods has caused skin rashes and decreases in white blood cells.-I HAVE SEEN NO RESEARCH THAT POINTS THIS OUT BUT SKIN RASHES WERE PROBABLY DUE TO LESS FATTY ACIDS FOR SKIN MAINTANANCE AND SOME ALLERGIC REACTIONS

How likely are dinitrophenols to cause cancer?

The Department of Health and Human Services (DHHS), the International Agency for Research on Cancer (IARC), and the EPA have not classified dinitrophenols for carcinogenicity. FOR GOOD REASON DNP HAS BEEN SHOWN TO NOT BE CARCINOGENIC

There are no studies available in people or animals on the carcinogenic effects of dinitrophenols.
WELL AREN'T WE LITTLE LIARS- THERE HAVE BEEN CANCER STUDIES IN ANIMALS 6 MONTHS AT HIGH EXPOSURE LEVELS IN MICE- NO CARCINOMAS

Is there a medical test to show whether I've been exposed to dinitrophenols?

Tests are available that measure the amount of DNPs or their breakdown products in blood, urine, and samples of tissue from the body. However, these tests may require special equipment and may not be available in your doctor's office.

Has the federal government made recommendations to protect human health?

The EPA recommends that not more than 70 parts of dinitrophenols per billion parts of water (70 ppb) be present in lakes or streams used for swimming.

The EPA lists DNPs as hazardous air pollutants (HAP) under the Clean Air Act. The EPA also requires that discharges or spills into the environment of 10 pounds or more be reported.

SOME EXTRA POINTS DNP IS ANTI PROTEOLYTIC- MUSCLE SPARING-

DNP IS STILL DANGEROUS IF TAKEN INCORRECTLY AND/OR WITHOUT THE PROPER PREPARATIONS. ITS USE IS NOT AN UNDERTAKING THAT SHOULD BE ENTERED INTO WITHOUT CONSIDERABLE KNOWLEDGE AND RESEARCH- KNOWLEDGE IS POWER.

BTW- DNP IS NOT FOR PREGNANT WOMEN- DNP IS A TERATOGEN- YOU SHOULD ALSO NOT TAKE IT AND HAVE SEX WITH YOUR PREGNANT WIFE OR GIRLFRIEND- EVEN SLEEPING IN THE SAME BED COULD BE HARMFUL BECAUSE YOU BREATH AND SWEAT OUT DNP ALL THE TIME- SO BASICALLY DONT TAKE IT IF YOUR SIGNIFIGANT OTHER IS PREGNANT

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MP

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macrophage69alpha
Moderator
(Total posts: 1194)
posted April 05, 2000 10:00 PM     Click Here to See the Profile for macrophage69alpha   Click Here to Email macrophage69alpha     Edit/Delete Message
bump

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MP

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ectomorph
Pro Bodybuilder
(Total posts: 145)
posted April 05, 2000 10:46 PM     Click Here to See the Profile for ectomorph   Click Here to Email ectomorph     Edit/Delete Message
THAT HAS TO BE THE BEST POST IVE READ YET!
DO NOT NOT NOT USE DNP!! IF YOU "NEED" IT QUIT BODYBUILDING BEFORE IT KILLS YOU.

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Pain is Weakness Leaving the Body

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macrophage69alpha
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(Total posts: 1194)
posted April 05, 2000 10:55 PM     Click Here to See the Profile for macrophage69alpha   Click Here to Email macrophage69alpha     Edit/Delete Message
once again ECTOMORPH
you misconstrue the intention and implications of the post
but each to his own
I can see how fat loss would not be important
to you- you are after all an ectomorph

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MP

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LittleSavage34
Pro Bodybuilder
(Total posts: 195)
posted April 05, 2000 11:02 PM     Click Here to See the Profile for LittleSavage34   Click Here to Email LittleSavage34     Edit/Delete Message UIN: 51221561
BUMP

Good post Macro...nice information.

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If you racked the bar, then you're lifting the bar.

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macrophage69alpha
Moderator
(Total posts: 1194)
posted April 06, 2000 12:51 AM     Click Here to See the Profile for macrophage69alpha   Click Here to Email macrophage69alpha     Edit/Delete Message
oxidative bump

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MP

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macrophage69alpha
Moderator
(Total posts: 1194)
posted April 06, 2000 02:03 AM     Click Here to See the Profile for macrophage69alpha   Click Here to Email macrophage69alpha     Edit/Delete Message
electron transport chain bump

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MP

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2legit2quit
Amateur Bodybuilder
(Total posts: 36)
posted April 06, 2000 11:34 AM     Click Here to See the Profile for 2legit2quit   Click Here to Email 2legit2quit     Edit/Delete Message
Its nice to have someone as knowledgeable as Macro on the board. I was wondering what DNP was and how it works...now I know. Thanks bro.

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macrophage69alpha
Moderator
(Total posts: 1194)
posted April 06, 2000 04:54 PM     Click Here to See the Profile for macrophage69alpha   Click Here to Email macrophage69alpha     Edit/Delete Message
BUMP FOR THE KING OF FATBURNERS
OF COURSE, KEEPING IN MIND THAT HE CAN BE
A HARSH AND MERCILESS KING

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MP

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macrophage69alpha
Moderator
(Total posts: 1194)
posted April 07, 2000 07:37 AM     Click Here to See the Profile for macrophage69alpha   Click Here to Email macrophage69alpha     Edit/Delete Message
bump

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MP

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ectomorph
Pro Bodybuilder
(Total posts: 145)
posted April 07, 2000 02:06 PM     Click Here to See the Profile for ectomorph   Click Here to Email ectomorph     Edit/Delete Message
Once again?? I dont think Ive misssed anything. Ive had first hand experience with people on DNP and one slightly overweight girl who was "interested in fat loss" died.
If you need poison to lean then you should QUIT bodybuilding before it kills you.
I mean honestly, if your diet, cardio, and cutting cycle dont get you there...Most of the top pros are still very leary of this substance,yet its touted on the boards as something everyone over 10 percent bf should use.

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Pain is Weakness Leaving the Body

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macrophage69alpha
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(Total posts: 1194)
posted April 07, 2000 02:28 PM     Click Here to See the Profile for macrophage69alpha   Click Here to Email macrophage69alpha     Edit/Delete Message
ECTOMORPH
I am sorry to say but I dont beleive you at all- If someone had died from DNP poisening(related to dieting) it would be plastered all over the papers. I know people who have taken inhuman amounts of DNP- so far the only person that I know who has had any problems-acute short term is a aquaintance who got severe edema from drinking only 2 cups of water/day

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MP

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ectomorph
Pro Bodybuilder
(Total posts: 145)
posted April 07, 2000 02:34 PM     Click Here to See the Profile for ectomorph   Click Here to Email ectomorph     Edit/Delete Message
Her name was Shelly Vandiver and in my city it was all over the papers. And frankly I dont give two shits what you believe. You strike me as someone who believes bodybuilding is more of a sciece of drugs(which is PARTIALLY true) than of Hard Work. And I dont believe youve seen people take INHUMAN doses of real DNP as the fatal dose is very close to that of the dose required for fat loss. But for you I say Go FOR IT!! eat tons of it. when they autopsy your body and your internal organs are still getting hotter( just like Shelly ) youll understand that it just wasnt worth it.

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Pumped_39428
Amateur Bodybuilder
(Total posts: 5)
posted April 07, 2000 02:41 PM     Click Here to See the Profile for Pumped_39428   Click Here to Email Pumped_39428     Edit/Delete Message
Macro. e-mail me when you have time. I have a few questions for you. Thanx!!!

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macrophage69alpha
Moderator
(Total posts: 1194)
posted April 07, 2000 03:32 PM     Click Here to See the Profile for macrophage69alpha   Click Here to Email macrophage69alpha     Edit/Delete Message
I find that very interesting as I could not even find a mention of her death at all in your local paper(the wonders of the internet)perhaps you mis-spelled her name- however I will take you at your word that you beleive that is what killed her- even though no one ever died from it during the time it was freely prescribed during the late 30's. I do not beleive that drugs are the end all be all of physique enhancement- I have been lifting for over 14 years and have only recently begun advocating chemical manipulation- the reason for this is that these are tools to help you achieve your goals- a tool undiscovered or shunned cannot benifit you and is wasted- and that tool might be the one thing that clinches the success of your program. If I were on here advocating eating lots of protein would you accuse me of the same thing- eating too much protein can kill you too, drinking too much water can drown you- so I guess what exactly is your point? I know of, not personally, plenty of people who have died from drinking alcohol- do you drink alcohol?
AND LASTLY THE RANGE BETWEEEN THE DOSES FOR FAT LOSS AND THE DOSES THAT CAN KILL YOU ARE ACTUALLY VERY WIDE- UNLIKE YOU I REALIZE THAT PEOPLE ARE GOING TO TAKE DNP ONE WAY OR THE OTHER- I PREFER THAT THEY DO SO IN AN INFORMED MANNER- I will add that your understanding of DNP, its effects, and mechanisms is NOT informed.
Peace

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MP

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macrophage69alpha
Moderator
(Total posts: 1194)
posted April 07, 2000 06:11 PM     Click Here to See the Profile for macrophage69alpha   Click Here to Email macrophage69alpha     Edit/Delete Message
bump

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MP

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macrophage69alpha
Moderator
(Total posts: 1194)
posted April 08, 2000 02:40 PM     Click Here to See the Profile for macrophage69alpha   Click Here to Email macrophage69alpha     Edit/Delete Message
BUMP

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MP

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efigy
Amateur Bodybuilder
(Total posts: 77)
posted April 08, 2000 02:48 PM     Click Here to See the Profile for efigy   Click Here to Email efigy     Edit/Delete Message
bump,
this is important info.
I agree with you macro, no matter what
you say someone will do whatever they
feel like doing.

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--
eFiGy

"conan, what is best in life?"
"TO CRUSH YOUR ENEMIES, TO SEE THEM DRIVEN BEFORE YOU, AND TO HEAR THE LAMENTATION OF THE WOMEN!!!"

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macrophage69alpha
Moderator
(Total posts: 1194)
posted April 09, 2000 11:58 PM     Click Here to See the Profile for macrophage69alpha   Click Here to Email macrophage69alpha     Edit/Delete Message
bump

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MP

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studcj
Pro Bodybuilder
(Total posts: 498)
posted April 10, 2000 12:31 AM     Click Here to See the Profile for studcj   Click Here to Email studcj     Edit/Delete Message
Ectomrph,
I am proud to say that Macro is right and you are wrong. You did misconstrue the post buddy. Is that you snowflake? I mean skinnyguy? I mean skinnyflake? Oops, I mean "G"? hehe.....

Great post macro, we need to bump this one for a long time!

BBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBB
UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU
MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMM
PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP
!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

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"I can, because Im crazzy!"
Studcj

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quake
Amateur Bodybuilder
(Total posts: 9)
posted April 10, 2000 12:52 AM     Click Here to See the Profile for quake     Edit/Delete Message
can I get a bump?

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