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  A quick tidbit...

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Author Topic:   A quick tidbit...
Stew Meat

Elite Bodybuilder

Posts: 709
From:Louisiana
Registered: Jul 2000

posted March 27, 2001 01:13 PM

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Progesterone DIRECTLY inhibits LH.

Estrodiol (from the conversion of testosterone) doesn't. So the way that Deca (nandralone) inhibits the HPTA is totally different than the way that test. does. So, when you think about how androgen levels in general are monitored by the hypothalamus and when levels are high, the hypo inhibits the release of LHRH from the posterier pituatary in conjunction with progesterone's direct antagonization of LH receptors in the leydig cells, I come to this conclusion...

Deca may supress the HPTA more than testosterone... Or maybe not.

Just a little FYI


-Stew


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eclass

Amateur Bodybuilder

Posts: 97
From:
Registered: Jan 2000

posted March 27, 2001 02:41 PM

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o


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Stew Meat

Elite Bodybuilder

Posts: 709
From:Louisiana
Registered: Jul 2000

posted March 27, 2001 05:07 PM

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bump


-Stew


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Fonz

Elite Bodybuilder

Posts: 1294
From:Mt. Olympus
Registered: Jun 2000

posted March 27, 2001 05:12 PM

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quote:
Originally posted by Stew Meat:
Progesterone DIRECTLY inhibits LH.

Estrodiol (from the conversion of testosterone) doesn't. So the way that Deca (nandralone) inhibits the HPTA is totally different than the way that test. does. So, when you think about how androgen levels in general are monitored by the hypothalamus and when levels are high, the hypo inhibits the release of LHRH from the posterier pituatary in conjunction with progesterone's direct antagonization of LH receptors in the leydig cells, I come to this conclusion...

Deca may supress the HPTA more than testosterone... Or maybe not.

Just a little FYI


-Stew



Thats why RU-486+Deca= NO DECA DICK!!!!!

Godspeed


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macrophage69alpha

Moderator

Posts: 1823
From:San diego, CA
Registered: Jan 2000

posted March 27, 2001 08:32 PM

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Nandralone is the most suppresive AS(aside from miblerone) with respect to the HPTA. In some cases normal Gonadrotropic activity was not restored for up to 13 months after end of usage, even with the concurrent use of HCG and Clomid.

------------------
MP


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macrophage69alpha

Moderator

Posts: 1823
From:San diego, CA
Registered: Jan 2000

posted March 27, 2001 08:34 PM

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Whether RU-486 will inhibit this suppresion is unclear- it might. However the progestagenic nature of DECA- increased fluid in joints and increased IM FAT- is part of the reason for its popularity. Use of RU-486 would seem to severely diminish or even eliminate those benefits.

------------------
MP


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Fonz

Elite Bodybuilder

Posts: 1294
From:Mt. Olympus
Registered: Jun 2000

posted March 27, 2001 08:55 PM

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quote:
Originally posted by macrophage69alpha:
Whether RU-486 will inhibit this suppresion is unclear- it might. However the progestagenic nature of DECA- increased fluid in joints and increased IM FAT- is part of the reason for its popularity. Use of RU-486 would seem to severely diminish or even eliminate those benefits.




Not correct. RU will block progestins, however
will not affect joints if used at around 1mg/Kg every
3 days, and as a bonus will inhibit cortisol by a
small degree that will decrease protein broken
down(anti-catabolic), leading to more gains.

Godspeed


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macrophage69alpha

Moderator

Posts: 1823
From:San diego, CA
Registered: Jan 2000

posted March 27, 2001 10:40 PM

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FONZ,

Please dont start your post with NOT CORRECT, unless you are willing to back that up with some evidence. You may beleive that is the case, however to say that it is unequivocally the case is COMPLETELY UNSUBSTANTIED.

------------------
MP


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Fonz

Elite Bodybuilder

Posts: 1294
From:Mt. Olympus
Registered: Jun 2000

posted March 27, 2001 10:51 PM

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quote:
Originally posted by macrophage69alpha:
FONZ,

Please dont start your post with NOT CORRECT, unless you are willing to back that up with some evidence. You may beleive that is the case, however to say that it is unequivocally the case is COMPLETELY UNSUBSTANTIED.




Hehe, I knew that would get you all riled up.....LOL
I have lab tests done on myself during my Deca
(1000mgs/week+RU) cycle, that prove my point.
The only problem is that I only have info from
10-11 people that have used RU-486.
But, I believe I'm still RIGHT. Just not enough
people have used RU to substantiate any thories.

Godspeed


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