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Anabolic Discussion Board Laying to rest the seeming abundant confusion over Clomid and Gonandotropin.
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Author | Topic: Laying to rest the seeming abundant confusion over Clomid and Gonandotropin. | ||
Elite Bodybuilder Posts: 1222 |
Im not certain what the confusion is all about, but allow me to illustrate my findings behind the use of these two drugs. Clomiphene Citrate (Clomid) is not a steroid, but a synthetic estrogen proscribed to stimulate ovulation in women. Its primary purpose within the school of bodybuilding is to restore hypothalamohypophysial testicular axis (HPTA). As we have all learned H-P-T-A function is suppressed through the use of exogenous androgens . Failure to restore H-P-T-A function can result in post cycle muscular atrophy (PCMA). Clomid does not mimic Lutenizing hormone (LH) nor does it mimic Follicle Stimulating Hormone (FSH), it simply induces their production, which in turn stimulates the leydig cells within the testies to begin the production of endogenous testosterone. Now, of utmost importance to bodybuilders is proper clomid timing. Obviously beginning 7-14 days of clomiphene therapy the last day of 500mg injection of sustanon would be a wasted endeavor since elevated blood androgen levels will still be present due in part to the deaconate ester in sustanon. Therefore, all of us must in good reason estimate the half-life/bioavailability of those hormones we administer in order to ensure that once LH/FSH production is began endogenously it doesn't become resuppressed once clomid ceases.
Gonadotropin is indeed used amongst men and women alike, but for completely different reasons. In women it is used during the third trimester of pregnancy during the last development of the ovum. Amongst men it�s used once again to bring about the production of testosterone. GONADOTROPIN mimics the effects of Lutenizing hormone. Therefore, its effects on the production are immediate because the biological process of inducing the production of LH (clomid) is omitted entirely. THE SINGLE MOST EFFECTIVE MEANS BY WHICH TO RESTORE H-P-T-A function is through the effective combination of both drugs. In most cases clomid alone will suffice, in most case *** alone will not suffice because it only mimics the effects of LH, which is not enough for permanent restoration of HPTA. PEACE
[This message has been edited by Twisted_Steel (edited March 27, 2001).] | ||
Elite Bodybuilder Posts: 1470 |
quote:
------------------ The moral? It doesn't matter whether you are a lion or a gazelle, when the sun comes up - you had better be running. | ||
Amateur Bodybuilder Posts: 155 |
Ah Yessssss.........Stelllllllllllle....you again amaze me with the research and clarification on such matters... BZR | ||
Elite Bodybuilder Posts: 692 |
Twisted, who knows, may be Clomid does just merely mimik LH and Animal is correct? Doesn't mean, of course, that we should stop using it postcycle, but may be using other agents, like he suggested will make recovery faster? | ||
Elite Bodybuilder Posts: 1222 |
I probably dont have the background in pharmacology that many of the better educated members do, hell I have no background in it. But, if clomiphene did what you propose then clomid and gonadotropin would be used interchangebly at every longevity clinque in the world. As far as my research and understanding goes the effects of these two drugs are precise and are not to be confused. One stimulates one mimics. ------------------ | ||
Elite Bodybuilder Posts: 692 |
I'm not pretending that I have any degree or even extensive knowledge, but practical application of Clomid is very interesting for me,for obvious reasons. I'm just trying to get to the bottom of the problem, to know, what is better for me to do. Just another day, reading through http://www.directweb.net/steroids/ discussion board, I found this statement, by Dr.Mark(really don't know his credibility,just passing information alone,don't kill the messanger!): -------------------------------------------- Clomid does not stimulate the hypothalamus. Ultimately the brain will have to decide when you truly recover the natural production of testosterone. And you cant begin a new cycle until you have fully recovered. Clomid delays the ultimate recovery at the brain (hypothalamus). Neurotransmitters carry signals to the hypothalamus telling it whats going on. We call this the suprahypothalamic level of stimulation. If you can stimulate the hypothalamus, then you are truly getting to the root of the problem. I have a whole section about suprahypothalamic stimulation in the physicians text: Anabolic Strategies and Treatment Applications |
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