From that post I noticed that quite a few of the guys who had problems with gyno had no problems with protruding guts.

However there were guys including myself who have no problem with gyno, but get the protruding guts.

Originally I thought it was just because of the oral 17aa steroids, but on find the web site below, I realise that it could have more to do with the Androgen/Estrogen balance.
http://www.antiaging.com/cyberhealth/CyberHealth_11.htm

If you read this site carefully you will notice that Estrogen is essential to maintain proper digestion.

Basically low estrogen levels coupled with high androgen levels causes stomach bloating due to improper digestion of food.

just my opinion

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Originally posted by macrophage69alpha:
IT IS ON THE THIRD PAGE BECAUSE IT IS WORTHLESS.... wild conclusions drawn from a vague article of are little value

just my opinion

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Originally posted by yiyangzhi:
I think Iron-Game started this interesting notion that estrogen is anabolic a few weeks back.

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My name is mentioned and I felt like I needed to clarify something here. That post did not go on to say that estrogen was anabolic but rather estrogen may play a role in promoting an anabolic state by affecting glucose utilization in muscle tissue. Alot of posts on estrogen lately and how to get rid of it and how to avoid it etc. What the issue is is not whether or not estrogen is anabolic but what is the optimal level for the body to have. As for people wishing to inject estrogen?

The way in which it said it may play a role in promoting an anabolic state by affecting glucose utilization was as follows:

"This occurs via an altering the level of available glucose 6-phosphate dehydrogenase. G6PD is an important enzyme in the support anabolism, as it is directly tied to the use of glucose for muscle growth and recuperation

During the period of regeneration after skeletal muscle damage, levels of G6PD are shown to rise dramatically. G6PD enzyme plays a vital role in what is known as the pentose phosphate pathway, and as such this rise is believed to enhance the PPP related process in which nucleic acids and lipids are synthesized in cells; fostering the repair of muscle tissue".

Peace

Essentially, what bodybuilders want to do is utilize the best aspects of the hormones involved in muscle anabolism and reduce the effects of the non-desirable ones. We love testosterone, but it aromatizes into estrogen. Estrogen helps increase GH and IGF, but it causes gyno and fat accrual. The remedy: Use test, with arimidex and GH. Problem solved.

Horm Res 1996;45(1-2):74-80

"Sex steroids, growth hormone, insulin-like growth factor-1: neuroendocrine and metabolic regulation in puberty."

Mauras N, Rogol AD, Haymond MW, Veldhuis JD

Nemours Children's Clinic, Jacksonville, Fla, USA.

The control of the onset of puberty involves the complex interaction of pituitary and gonadal hormones. At a preprogrammed time in a child's life there is an increase in the amplitude of GnRH pulses which triggers a cascade of events including increases in the amplitude of FSH and LH pulses, followed by marked increases in gonadal sex steroidal output, which in turn increases growth hormone (GH) and insulin-like growth factor-1 (IGF-1) production. Evidence suggests that there is an integral interaction between the endogenous opiate system and the hypothalamic-pituitary-gonadal axis, at least in the later stages of puberty in the male. Both androgenic and estrogenic hormones markedly increase GH production rates as measured by deconvolution models in the prepubertal human, and compelling data strongly suggest that it is indeed the estrogen which controls the feedback amplification of GH production during puberty even in the male. It appears that the prepubertal gonad is actively producing sex hormones which might be important in the control of GH production since early childhood. The translation of these neuroendocrine rhythms into distal metabolic actions is also reviewed. Utilizing isotopic tracer infusions of the essential amino acid leucine, studies clearly show a selective stimulation of whole body protein synthesis by both GH and IGF-1. GH, IGF-1 and androgenic hormones all increase in puberty, stimulating whole body protein anabolism during that period. However, we observed no protein-anabolic effect in the hypogonadal female given increasing doses of estrogen. The latter suggests that at least as it pertains to whole body protein effects, the action of androgens is probably mediated via the androgen and not the estrogen receptor, in clear distinction from the estrogen-mediated effects of androgens on the neuroendocrine axis. Calcium absorption and retention are also positively affected by the androgens as shown by significant increases in calcium absorption and retention after the administration of testosterone to the prepubertal male. This suggests an important role of sex steroidal hormones in the mineralization of the skeleton. In conclusion: GH, IGF-1 and sex steroids all markedly increase during puberty and their actions are amplified mutually as they control growth, increase muscle mass and affect the mineralization of the skeleton. The dichotomy of androgen and estrogen effects in the male and female may regulate the differential timing of the onset of puberty and final height in the two sexes. The synergistic actions of these anabolic hormones appear to be most significant during the finite years of puberty.

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Originally posted by macrophage69alpha:
IT IS ON THE THIRD PAGE BECAUSE IT IS WORTHLESS.... wild conclusions drawn from a vague article of are little value

just my opinion

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