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  Got somethign for MeanOne... research on Anadrol

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Author Topic:   Got somethign for MeanOne... research on Anadrol
Stew Meat

Elite Bodybuilder

Posts: 628
From:Louisiana
Registered: Jul 2000

posted March 10, 2001 07:18 PM

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"A new study shows that one of the most powerful oral anabolic steroids improves lean muscle mass with no significant side-effects. (1) Oxymetholone, formerly sold in the US as Anadrol-50, was given for thirty weeks at a 150 mg/daily dose. Weight gain averaged 14.5% of bodyweight, which is significant because there was no exercise program instituted, but it is known that anabolic steroids exert their greatest effect when weightlifting is employed.

While oxymetholone is considered to be a harsh steroid with a high potential for side-effects, the subjects were reported to have no significant problems with liver function, water retention, virilization, and several side-effects thought to be associated with its use, at a dose that is three times what many bodybuilders would use, for considerably longer than they would generally use it.

The study didn�t look at CD8+ T cell counts, which appear to be more correlative with survival than CD4+ T cells,(2) which were not correlative with weight gain in this study."

1. Oxymetholone promotes weight gain in patients with advanced human immunodeficienty virus (HIV-1) infection. Hengge, et al. Brit J Nutri (1996) 75:129-138]


-Stew


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300kleen

Guru

Posts: 5093
From:
Registered: Aug 1999

posted March 10, 2001 07:20 PM

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Nice post Stew.
That's 29lbs for a 200lb person. Not bad for not working out.

------------------
300 kleen


[email protected]

Check out this website:Steroid Information, Pofiles, & Pictures


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MeanOne

Elite Bodybuilder

Posts: 801
From:
Registered: Dec 2000

posted March 10, 2001 09:07 PM

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I can't recall where I read that from, but I know I've seen that before. Either way, good to hear somebody else has found a study to suggests that anadrol may not be the bain of steriods.


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ultragainz

Elite Bodybuilder

Posts: 1026
From:from the underground
Registered: Aug 2000

posted March 10, 2001 09:09 PM

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nice bro.........later

------------------
NO SWEAT!!! NO BLOOD!!! NO TEARS!!!
AND THATS THE BOTTOM LINE!!!!!
P.S.GAMEOVER!!!!!


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BigBald-1

Amateur Bodybuilder

Posts: 147
From:
Registered: Jun 2000

posted March 10, 2001 10:09 PM

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I am taking it 100mg per day and prefer it to Dbol 50 mg a day


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macrophage69alpha

Moderator

Posts: 1746
From:San diego, CA
Registered: Jan 2000

posted March 11, 2001 01:03 AM

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those gains are seen in patients with HIV... perhaps you should take this into consideration before going off on a pro- anadrol craze.

------------------
MP


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Daeo

Elite Bodybuilder

Posts: 959
From:Haddonfield, ILL
Registered: May 2000

posted March 11, 2001 01:06 AM

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But would you say 150mg or anadrol promoted more growth than 150mg of dbol...

------------------


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lawnsaver

Olympian

Posts: 1878
From:FL
Registered: Sep 2000

posted March 11, 2001 01:08 AM

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A similar study was done with 600mg of enanthate given for 10 weeks. The guys averaged 13lbs over the 10 weeks peroid with no training program.

------------------
" That which does not kill me, will make me stronger"

"Catch a man a fish, he eats for a day. Teach a man to fish, and he eats for a lifetime."


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barbells79

Pro Bodybuilder

Posts: 319
From:CINTI- OHIO
Registered: Jan 2001

posted March 11, 2001 01:23 AM

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i agree, nice post and informative as well.

------------------
;what we do in life echoes in eternity;


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macrophage69alpha

Moderator

Posts: 1746
From:San diego, CA
Registered: Jan 2000

posted March 11, 2001 02:00 AM

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the enanthate study was done in healthly subjects.

the non training control group gained avg. 7lbs(i think, actually might have been more) lean mass

------------------
MP


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Fonz

Elite Bodybuilder

Posts: 869
From:Mt. Olympus
Registered: Jun 2000

posted March 11, 2001 04:27 AM

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Stew no offense, but that particular study was
debated for hours by myself and meanOne.
Oh, and MeanOne, the guy who orignally posted
it was Panerai, I remember. All I'm going
to say is that particular study does not qualify as
evidence o suggest Anadrol is benign, as you
don't see many underweight HIV positive
bodybuilders running around. Hell, at
the time even MeanOne agreed with me. I willl
re-iterate what our conclusions about anadrol
were:

1. It doesn't cause liver damage at dosages
rangingfrom 1mg/Kg to 5mg/Kg

but, here is the kicker

2. IT IS THE ONLY ORAL STEROID LINKED
TO CANCER AT A DOSE OF ONLY 3MG/KG

MeanOne also agreed on this point.
So stew, do me a favour and read the actual
study before posting such a farciccal
document.
(no flame intended)

Godspeed


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MeanOne

Elite Bodybuilder

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posted March 11, 2001 05:44 AM

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Okay, hold the fuck on here. That study said the subjects had no adverse side effects, water retention, acne or all the other crap you guys talk about Anadrol. Their liver enzymes were fine! More over, I don't care if someone has aids or not, if they didn't retain water, didn't grow progestrogen breasts, they didn't. The weight gain is not important, we all know multiple drugs will pack on the mass, the study just suggests that in this case, the often talked about side effects are mostly rumor, with only partial truth.

Fonz, I'm been thinking about the study with the lab rats...then I picked up some biology books, and I have come to find that the liver of a rat is nearly %150 smaller per ounce of bodyweight, than that of a human. This alone suggests that the animal couldn't use the same dosages as a human per ounce, or kg. Just something I thought might raise your eyebrow.

We don't need to debate this...I've done 10/day, and I have had no liver problems, and am walking around fine. Maybe some can't, I can, and as long as I'm not dying of liver cancer, then guess what...I don't care what a study done on animals with livers 150% smaller per ounce of bodyweight can safely use, because that fact alone makes the study bunk.

Thanks and have a nice evening.
(Great post Stew!!!!)


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Fonz

Elite Bodybuilder

Posts: 869
From:Mt. Olympus
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posted March 11, 2001 06:30 AM

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Interesting comparison between the rat liver and
a human liver. That does deserve further research.
But you still have to agree the study Stew posted is
complete garbage in regards to Anadrol use in
healthy bodybuilders. I'm not disagreeing with you
on the liver issue, regarding anadrols hepatoxic
effects, its just we've yet to come accross a bonafide
anadrol study regarding healthy males at dosages
exceeding 300mgs/day.

Godspeed


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Stew Meat

Elite Bodybuilder

Posts: 628
From:Louisiana
Registered: Jul 2000

posted March 11, 2001 05:44 PM

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No, Fonz, I do not appreciate the flame and it does not make you look smarter than you actually are.

quote:
the guy who orignally posted
it was Panerai, I remember.

I could care less is someone else posted this info before me. I came across this research in my reading and decided to post it as others may have not seen the Panari post as I have not.


quote:
it was Panerai, I remember. All I'm going
to say is that particular study does not qualify as
evidence o suggest Anadrol is benign, as you
don't see many underweight HIV positive
bodybuilders running around.

What is this supposed to mean? The fact that bodybuilders are not underweight has nothing to do with the effects of liver toxicity and other findings of this study that support Anadrol use.

quote:
Stew no offense, but that particular study was debated for hours by myself and meanOne.

Well, you don't seem to agree or sound like there was a debate for hours on the topic as you don't seem to have any of the same conclusions in your posts.


quote:
So stew, do me a favour and read the actual study before posting such a farciccal
document.

Again, critisism does not make you sound like you are intelligent. How about do ME a favor and read the actual study before offering your uneducated comments about its specifics. I provided the refrence. If you HAD read the actual article, you would have noticed that the HIV+ individuals that it used had no AIDS related side effects. They may very well have been bodybuilders. HIV+ does not = AIDS. The study consisted of healty young adults. You may be interested to know (if you had read the actual research) that there was a subgroup that contained patients WITH AIDS related symptoms and the anabolic effect was significant but not was not as prominant as in those healthy individuals.

-Stew


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Fonz

Elite Bodybuilder

Posts: 869
From:Mt. Olympus
Registered: Jun 2000

posted March 11, 2001 06:07 PM

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quote:
Originally posted by Stew Meat:
[B]No, Fonz, I do not appreciate the flame and it does not make you look smarter than you actually are.

[QUOTE]the guy who orignally posted
it was Panerai, I remember.

I could care less is someone else posted this info before me. I came across this research in my reading and decided to post it as others may have not seen the Panari post as I have not.


quote:
it was Panerai, I remember. All I'm going
to say is that particular study does not qualify as
evidence o suggest Anadrol is benign, as you
don't see many underweight HIV positive
bodybuilders running around.

What is this supposed to mean? The fact that bodybuilders are not underweight has nothing to do with the effects of liver toxicity and other findings of this study that support Anadrol use.

quote:
Stew no offense, but that particular study was debated for hours by myself and meanOne.

Well, you don't seem to agree or sound like there was a debate for hours on the topic as you don't seem to have any of the same conclusions in your posts.


quote:
So stew, do me a favour and read the actual study before posting such a farciccal
document.

Again, critisism does not make you sound like you are intelligent. How about do ME a favor and read the actual study before offering your uneducated comments about its specifics. I provided the refrence. If you HAD read the actual article, you would have noticed that the HIV+ individuals that it use

"....uneducated comments......"

That just made my day. Oh well, 4 years of University
down the drain........

Godspeed



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beefmaster

Amateur Bodybuilder

Posts: 292
From:outerspace
Registered: Sep 2000

posted March 11, 2001 06:15 PM

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Jeeeeez, go out back and beat the shit out of each other but stop playing the teenybopper routine for all to read.


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MeanOne

Elite Bodybuilder

Posts: 801
From:
Registered: Dec 2000

posted March 11, 2001 06:41 PM

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So, let me get this straight. If a person was to have the flu, and didn't have side effects from anadrol, you couldn't SUGGEST that a health person, or a person with down syndrom would also not have side effects? If anything I would think having aids would increase the demands placed on the liver for various reasons...
An illness does not stop hormone conversion or water retention...aids or otherwise.

Fonz, we can sit and argue for hours (We spent an entire day in 3 posts doing so Stew, it was classic), but you know what, when it comes right down to it, if you can't use anadrol because of genetic inferiorities you have, but I can, more power too me. However, if primobolan was to produce excellent gains for you, and not so for me, more power to you. Basicly, use what works good for you. Stew just posted that because it partially suggests that the sides may not be all that they are cracked up to be.

-Meanie-


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Fonz

Elite Bodybuilder

Posts: 869
From:Mt. Olympus
Registered: Jun 2000

posted March 11, 2001 06:43 PM

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I respectfully agree MeanOne.

<bye>



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Stew Meat

Elite Bodybuilder

Posts: 628
From:Louisiana
Registered: Jul 2000

posted March 11, 2001 06:46 PM

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Fonz, I did not mean that you were "uneducated" in general. I only meant that you were uneducated as to the details of this experiment. I wasn't trying to be a butt... well, not to that extent

-Stew


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Fonz

Elite Bodybuilder

Posts: 869
From:Mt. Olympus
Registered: Jun 2000

posted March 11, 2001 07:00 PM

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Thanks stew, but it really isn't necessary...
I think I'll just make a quiet exit. I haven't got
the time and ressources to help newbies if all
I get is blatant disrepectfulness. This isn't
directed to you, just some people.

Godspeed


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white boy

Amateur Bodybuilder

Posts: 93
From:
Registered: Jan 2001

posted March 11, 2001 07:16 PM

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quote:
Originally posted by Fonz:
Thanks stew, but it really isn't necessary...
I think I'll just make a quiet exit. I haven't got
the time and ressources to help newbies if all
I get is blatant disrepectfulness. This isn't
directed to you, just some people.

Godspeed



IMPLANT GUN, LOL


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MeanOne

Elite Bodybuilder

Posts: 801
From:
Registered: Dec 2000

posted March 11, 2001 07:20 PM

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Fonz, let's be fair. You did make the first assult on Stew about posting the study. I mean, when you snack someone in the face, expect them to hit you back, so to say. I'm not blaming you, or anything along those lines, you stated your opinions, just not in a manner to promote a high level of respect and peace.

What the hell is he talking about...implant gun? WTF?


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Fonz

Elite Bodybuilder

Posts: 869
From:Mt. Olympus
Registered: Jun 2000

posted March 11, 2001 07:33 PM

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quote:
Originally posted by white boy:

IMPLANT GUN, LOL



White boy, I posted the implant gun thread on
Dec.26. You hadn't even registered then,
so please go crawl back under from were you
came from..
And MeanOne, I know I lost my cool with Stew,
but I'm starting to get tired of all the bashing
that happens on the board. I've probably
helped dozens of people out, and all I get
is flames. Oh well, not for much longer....

Godspeed


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white boy

Amateur Bodybuilder

Posts: 93
From:
Registered: Jan 2001

posted March 11, 2001 08:19 PM

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quote:
Originally posted by MeanOne:

What the hell is he talking about...implant gun? WTF?


fonz was whining about always getting dissed I thought maybe this is why
https://www.elitefitness.com/ubb/Archives/Forum1/12-2000/042438.html


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cockdezl

Elite Bodybuilder

Posts: 635
From:
Registered: 2000

posted March 12, 2001 12:52 AM

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"those gains are seen in patients with HIV... perhaps you should take this into consideration before going off on a pro- anadrol craze."

True, MACRO, the gains seen in HIV subjects is most probably exacerbated by their cachexia, but the real question is, "Were they on any of the anti-HIV combos while using oxymetholone?" I would be impressed if they were still using the anti-HIV meds and showed no liver abnormalities with oxymetholone, which all together should have been a whopper of a liver burden.


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bigrand

Pro Bodybuilder

Posts: 378
From:
Registered: Sep 2000

posted March 12, 2001 02:51 AM

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Hepatocellular carcinoma associated with anabolic steroid therapy: report of a case and review of the Japanese literature.

Kosaka A, Takahashi H, Yajima Y, Tanaka M, Okamura K, Mizumoto R, Katsuta K

Department of Surgery, Matsusaka City Hospital, Mie, Japan.

We report herein the case of a 35-year-old woman with aplastic anemia who developed hepatocellular carcinoma after long-term therapy with oxymetholone. She was treated with 60 mg/day of oxymetholone for 3 years (total dose 64.8 g). Alpha-fetoprotein, hepatitis B surface antigen, and hepatitis C antibody were all negative, but serum titers of carcinoembryonic antigen and carbohydrate antigen were elevated. Lateral segmentectomy of the liver was performed. The histopathological findings were compatible with those of multiple hepatocellular carcinoma without liver cirrhosis. Three years since the operation, the patient is doing well and no signs of tumor recurrence have been detected. According to our review of Japanese cases of hepatocellular carcinoma associated with anabolic steroid therapy, in all instances the tumors developed after long-term administration of anabolic steroids for hematologic diseases. In patients under long-term anabolic steroid therapy, routine screening of the liver by ultrasonography and computed tomography should be performed to detect liver tumors in the early stages.

Heres you Abomb liver cancer


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bleedo

Cool Novice

Posts: 45
From:
Registered: Jan 2001

posted March 12, 2001 03:03 AM

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.....60 mgs. a day for THREE YEARS?
I would guess that 60mgs.ED for three years
of just about any AS could lead to liver cancer...

------------------
Courage is fear that has said
its prayers...


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Fonz

Elite Bodybuilder

Posts: 869
From:Mt. Olympus
Registered: Jun 2000

posted March 12, 2001 08:27 AM

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quote:
Originally posted by bleedo:
.....60 mgs. a day for THREE YEARS?
I would guess that 60mgs.ED for three years
of just about any AS could lead to liver cancer...




I challenge that statement. Out of all the orals
out there only oxymetholone has been proven
to cause Cancer(and yes it was only in rats).
And re-examining that study, the dose given
was 60mg/day. Now, lets assume she's a
skinny 35-year old woman and weighs around
60Kg. THATS ONLY A DOSE OF 1mg/KG.
AND IT CAUSED CANCER AFTER ONLY
THREE YEARS.
Definately need some more feedback on this,
as this is a very interesting study albeit a bit
small(n=1).

Godspeed


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bigrand

Pro Bodybuilder

Posts: 378
From:
Registered: Sep 2000

posted March 12, 2001 03:32 PM

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Oxymeth os the ONLY AAS ive read about leading to cancer. All others lead to benign legions that regress when the drug is no longer taken, or other liver problems, but not carcinomas.


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MeanOne

Elite Bodybuilder

Posts: 801
From:
Registered: Dec 2000

posted March 12, 2001 05:37 PM

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Gee, should I even bother mentioning that there are some people who drink on a daily basis for only 8-10 months and develope liver problems, and that there are some people who drink every day, all their lives, and live to 100, with no liver problems. Naw, I'll just keep quiet about that, lol.


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