posted February 26, 2000 11:26 AM         

When you put a ******* ester into the muscle, the oily solution slowly
disperses into surrounding tissues. An enzyme slowly detaches the *******
from the organic acid group (the decanoate, enanthate, cypionate, etc.) at
a rate that is dependent on the concentration of the original ester
(approximately) and the length of the acid chain. Once detached from the
acid group, the ******* enters the blood stream because it has a (small)
solubility in water (blood). The blood concentration of ******* is what is
important to the processes that lead to growth. After administration of a
******* ester, it usually takes a day for the blood concentration to reach
a maximum, then it starts to decrease. The time at which the concentration
is one-half of the max is considered the half-life.

Knowing the kinetics of the de-esterification reaction, one can calculate
how much of the original ester is freed-up each day. For test enanthate,
the half-life is considered to be 6 days (some say 5 days). If 1,000 mg of
test enanthate is administered on day 0, then by day one, approximately 110
mg have been de-esterified (11% of 1,000), which frees up about 77 mg of
testosterone (about 70% of the test-enanthate molecule) to enter the
bloodstream over this 24 hour period. On day two, about 98 mg of the
enanthate is de-esterified (11% of the amount left from day 1), freeing up
about 69 mg of testosterone to enter the bloodstream, and so forth. If you
compare these levels of test entering the bloodstream to the amount of
prohormones that some people take (1-2 grams per day), you can see that the
liver is actually capable of metabolizing the test to byproducts quite
easily (a single administration of 1 gram of androstenediol will be 95%
metabolized by the liver in the FIRST PASS). If the liver can readily
degrade 950 mg of prohormone in one pass, it can easily handle 77 mg over a
24 hour period. Liver stress is caused by the 17-alpha-alkylated *******s
(orals), not the typical injectables.

Is 1,000 mg/wk a lot? Well, in terms of the amount of test that gets into
your bloodstream relative to the amount that is there naturally, YES, 1,000
mg/wk is a lot. Is it toxic? NO.

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GET OFF ME!!
GET BIG GUY'S!!!!!!!!!

posted February 26, 2000 11:38 AM            

Jon