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  T3 and thyroid shutdown

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Author Topic:   T3 and thyroid shutdown
d1734

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posted January 11, 2001 07:54 PM

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Why is the thyroid so sensitive to T3 in comparison to the HPTA? The systems seem Identical. With testosterone it goes Hypothalamus-->LH-->Testosterone and w/ the thyroid it goes Hypothalamus-->TSH-->T4. (I think, don't feel like looking it up so don't cut my head off if I'm slightly wrong)

Why would high dose T3 shutdown the thyroid differently from high dose test shutting down the testicles?

Is there any evidence whatsoever that high dose T3 can shutdown the thyroid? (permanently)

I remember many people challenging others for evidence and no one could show the slightest bit.

[This message has been edited by d1734 (edited January 11, 2001).]


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Myomorph

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posted January 11, 2001 08:02 PM

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The amount of thyroglobulin secreted by the thyroid is controlled by the thyroid-stimulating hormone (TSH) of the pituitary gland. Pituitary TSH, in turn, is regulated by a substance called thyroid-stimulating hormone releasing factor (TRF), which is secreted by the hypothalamus.


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d1734

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posted January 11, 2001 08:04 PM

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ahh ok, knew i was forgetting something in there, the ol' pituitary.


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BigJay81

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posted January 11, 2001 08:17 PM

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The Governer Of the body.

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=http://pub33.ezboard.com/btherealjspad


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Until You Die!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!


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d1734

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posted January 12, 2001 12:33 PM

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bump


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d1734

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posted January 12, 2001 02:15 PM

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bump


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Cornellius

Pro Bodybuilder

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posted January 12, 2001 03:48 PM

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I have always wonder why there is no drug that can elevate endogenous thiroid hormone, like the way clomid does on the endogenous test.

------------------


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Cornellius

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posted January 12, 2001 05:17 PM

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Up!


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Cornellius

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posted January 12, 2001 05:23 PM

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Up!


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d1734

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posted January 12, 2001 06:59 PM

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amazing that no one responds...could it be thyroid shutdown is just another internet "jump on the bandwagon" myth?


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DreaDlorD

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posted January 12, 2001 07:03 PM

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Maybe...

but I'm not taking a chance till I know for sure.

With T3, 25 for 4 weeks, then 8 weeks off works well enough anyway.


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TEXASAMM

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posted January 12, 2001 07:10 PM

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I've taken 50mcg. a day for a couple months on a bulking cycle Blood tests revealed TSH low but inrange and T3,T4 inrange.All normal.


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BigJay81

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posted January 12, 2001 07:19 PM

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Its amazing isn't. lol
sucks when you try to ban someone

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d1734

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posted January 12, 2001 07:22 PM

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bigjay: grow up, don't let it bother you. g-man is the most pleasant person to talk to of anyone, that's why it made me very mad when all you guys jumped on the best internet source there is.


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d1734

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posted January 12, 2001 07:24 PM

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TEXASAMM: that's good to hear. i personally think 50mcg is probably ok permanently, makes ya wonder if 150mcg is too...


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BigJay81

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posted January 12, 2001 07:25 PM

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Last comment I make on this And I drop it for good.
Please don't use that person I don't want anyone in trouble from this board. Their are many better people to deal with.
Sorry if I offended you earlier I'm done with the topic and hope some one can anwser your question.
Goodluck
JAy


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d1734

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posted January 12, 2001 09:34 PM

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bump, come on you anti high dose T3 faction, i know you are out there.


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DREXX

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posted January 12, 2001 09:43 PM

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I am not against high dosages but I still would not use more than 75mcg.

Why...Is it really necessary?

You can get great results with diet, cardio a little ECA and T3.

I am also scared of shutting down my thyroid so I will stick to a max of 4-5 weeks.

Even if there is no evidence I prefer to play it safe

------------------
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d1734

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posted January 12, 2001 10:07 PM

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Drexx, Jason Mueller recommends 100mcg while BULKING! lol, wonder what he would say for cutting, havn't seen it. I don't think anyone knows for sure exactly what the benefits of the higher dosages are, Bill Roberts says there aren't many but I think he is dead wrong.

But come on, evidence is the basis for everything you can't just make accusations otherwise.


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DREXX

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posted January 12, 2001 10:22 PM

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I know what Mueller recommends and he is crazy

Nah! I read anabolicextreme every week and it's great.

I am not making accusations just stating that I personnaly wont go over 75mcg because it gives good results.

For bulking cycles I use it too but at 25mcg.

Is there a risk? I don't know. But I have no reason for taking that "potential" risk since I don't have too.

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cockdezl

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posted January 12, 2001 11:37 PM

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The problem with increasing dosage of T3 is the increase in non-thermogenic related processes, such as increases in proteolytic activity. So while you may get a little more caloric expenditure with a higher dose, you will also get more catabolic activity. This maybe the true origin of T3 related muscle catabolism, and I believe is the rationale that Roberts is using when he states that there is no increase in benefits with increased dosage over 50-75mcg.


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d1734

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posted January 12, 2001 11:46 PM

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cockdezl: is this true even in the presence of large amounts of steroids? What about the stacking of various thyroid hormones, like 100mcg T3 + 600mcg T2 + triac, etc.


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Cornellius

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posted January 13, 2001 12:44 AM

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Come on...
I know we have more knowledge on this board!!!

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Cornellius

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posted January 13, 2001 11:00 AM

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Bump


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jarabbit

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posted January 13, 2001 01:23 PM

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bump. any concerns running t-3 at 25 mcg for a full 2 months while bulking and then going into your normal t-3 type cycle for 6 weeks, a total time of 3.5 months? On gear the whole time. Also what benefits can one really expect from adding 25mcg's daily to a cycle?


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winstrol69

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posted January 13, 2001 01:49 PM

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This is what I got out of a doctor "I NEVER prescribe t-3 or t-4, its just to dangerous"


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Cornellius

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posted January 14, 2001 01:52 AM

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Up


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MICHLDAV

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posted January 14, 2001 03:36 AM

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Well this discussion has been on other boards before. I think it was on the renegade or somethink like this - someone was giving a reward($$$$) to anyone who could come up with some scientific report or study, prooving that thyroid shutdown acutally accours whith high dosage. No one did. Not that this concludes it doesn't happen, but it makes you wonder about the above mentioned 'bandwagon' thing.

Mike H / VIKING OF THE NORTH.

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My reply: Well kid, those plastic inflatable girls can't get pregnant anyway.


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Texas Guns

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posted January 14, 2001 07:55 AM

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Okay, I want the reward money, because yes, my thryroid did shut down due to the overuse of T3. My dunce of a doctor decided to put me on intense vitamin therapy (didn't work) because he thought I had a tendency to over dose any medication he would put me on. What would give him that idea? I was only up to 100 - 150 mcg's a day. Liked what it was doing so why not do more? WRONG!!!!!!!!!

So, I went on a cycle of Primobolan and it seemed to bring my system back to normal, though now I feel it is getting out of whack again. Don't have the $ for a doctor right now, so it looks like another cycle for me.


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Pumpmasterflex

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posted January 14, 2001 09:20 AM

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Sorry to hear that texas guns, what dosages did you use and how long for, for this to happen. Also in the W.A.R it says they can be a drastic decrease in muscle when cytomel is used, what are your views on this?


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Texas Guns

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posted January 14, 2001 10:03 AM

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T3 burns everything in it's path. Abundant protein intake is essential along with some other anabolic will help preserve muscle. In my opinion there has got to be a better option. With the right doseage and precautions, DNP is not a bad idea.

With my T3 I did not taper down like I should have and my doseage got up way too high. I in bed for close to a month and couldn't function for much longer after that. Be careful my friend and watch your doseage.


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Pumpmasterflex

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posted January 14, 2001 01:01 PM

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Thanks texas guns, i think the anabolic review underated the strong affect this drug can have after reading other posts.


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