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  RU-486 users out there?

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Author Topic:   RU-486 users out there?
bigrand

Amateur Bodybuilder

Posts: 278
From:
Registered: Sep 2000

posted January 04, 2001 06:16 PM

Staff Use Only: IP: Logged


I was wondering is anyone uses this for an anti-progesterone.
Also, here is an interesting piece on RU-486 for those interested.
RU-486 completely reversed the obesity of genetically obese (fa/fa) rats by blocking the effects of glucocorticoids and insulin causing excessive fat cell proliferation. RU-486 reduced fat storage from 1907 kj to 102 kj, while increasing protein (lean tissue) storage from 44 kj to 217 kj. (American Journal of Physiology 1990, R539-43)

RU-486 (mifepristone) reduces the deposition of fat tissue and increases the deposition of lean tissue, but only in obese subjects. RU-486 also causes obese mice to lose weight by increasing BAT thermogenesis. Reportedly RU-486 can help cure Cushing's syndrome, a gland disorder characterized by obesity and hypertension. "Potentially the most potent anti-aging drug available." (Longevity, Jan 1991)

A paper in the 1992 International Journal of Obesity reports that Norepinephrine (the neural transmitter, not the asthma drug) inhibits rat pre-adipocyte proliferation.


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