GEORGE SPELLWIN'S ANNOUNCEMENTS
Enlightening Men about Anabolic Steroids and Bodybuilding for over Two Decades
|
 Elite Fitness Bodybuilding, Anabolics, Diet, Life Extension, Wellness, Supplements, and Training Boards
 Anabolic Discussion Board
 Do AS that are more androgenic bond with the androgen receptors better than the...
|
| Author | Topic: Do AS that are more androgenic bond with the androgen receptors better than the... | ||
|
Pro Bodybuilder 
Posts: 333 |
AS with higher anabolic qualities? I was just thinking, if you are shooting 1000mgs of test and 400mgs of deca, alot of that test will be getting taken up but what happens to the deca? Just a thought ------------------     | ||
|
Elite Bodybuilder 
Posts: 861 |
Here is some information I posted some weeks back that I found in an article. Testosterone does not only increase protein synthesis but does many other things. This is why, I personally, believe test should be the base of any cycle. Testosterone: Enhanced protein synthesis Enhanced growth factor activity (e.g. GH, IGF-1, etc.) Enhanced activation of myogenic stem cells (i.e. satellite cells) Enhanced myonuclear number (to maintain nuclear to cytoplasmic ratio) New myofiber formation Starting with enhanced growth factor activity, we know that testosterone increases GH and IGF-1 levels. In a study by Fryburg the effects of testosterone and stanozolol were compared for their effects on stimulating GH release.2 Testosterone enanthate (only 3 mg per kg per week) increased GH levels by 22% and IGF-1 levels by 21% whereas oral stanozolol (0.1mg per kg per day) had no effect whatsoever on GH or IGF-1 levels. This study was only 2-3 weeks long, and although stanozolol did not effect GH or IGF-1 levels, it had a similar effect on urinary nitrogen levels. What does this difference in the effects of testosterone and stanozolol mean? It means that stanozolol may increase protein synthesis by binding to AR receptors in existing myonuclei, however, because it does not increase growth factor levels it is much less effective at activating satellite cells and therefore may not increase satellite cell activity nor myonuclear number directly when compared to testosterone esters. I will explain the importance of increasing myonuclear number in a moment, first lets look at how increases in GH and IGF-1 subsequent to testosterone use effects satellite cells. More myonuclei mean more receptors Summed up when stacking something with testosterone you are going to get more benefit and I do not believe that deca binds better than test. If this was the case then people would be using deca rather than test. They all extert their effects via different mechanismns though. ------------------ | ||
|
Elite Bodybuilder
Posts: 915 |
Iron_Game, DO you have that whole article? It's a good one and should probably be posted again in its entirely. ------------------ | ||
|
Pro Bodybuilder
Posts: 429 |
Not necessicarily, for instance, deca has a high affinity for the AR. | ||
|
Elite Bodybuilder
Posts: 1489 |
Great post! | ||
|
Guru 
Posts: 4995 |
Deca binds to the A/R about 3 times more effectively than test.Test is much more powerful outside of the A/R than deca.Primobolan shares similar binding characteristics to deca,although not quite as potent.Test is the most powerful because of its dual effectiveness(strong effects at the A/R and strong effects independent of the A/R)whereas the others are only strong in one mechanism,but completely lacking in another. [This message has been edited by HUCKLEBERRY FINNaplex (edited January 02, 2001).] |
All times are ET (US) | |
 |
|
|
posted January 02, 2001 03:49 AM
