I know Xenical gives you crazy shits, but conversely, I tend to overindulge on cheat-day, so I'm thinking that a xenical 2 hrs before may do what chitosan (and vanadyl but w/ fat vs carbs) were never able to...
To quote Mr Spellwin
So what about popping one before the xlarge pizza?
To quote Mr Spellwin
Xenical targets the absorption of fat in your body rather than suppressing your appetite. It is useful for long term use and has been shown to be effective for 1-2 years. Dietary fats are inhibited from being absorbed and this allows about 30% of the fat eaten in the meal to pass through the gut undigested. This helps you to reduce and maintain your weight, as well as to minimize any weight regain. I personally use Xenical on occasions where I have overindulged and want to minimize the "damage." One good thing about Xenical, is that it can be taken one hour before or up to two hours after a meal and is still effective.
So what about popping one before the xlarge pizza?