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Research Chemical SciencesUGFREAKeudomestic
napsgeargenezapharmateuticals domestic-supplypuritysourcelabsResearch Chemical SciencesUGFREAKeudomestic

Why was Boldenone never used for human consumption throughout history?

Judo Tom said:


eq armotizes into estrogen at some %

dbol armotizes into a methylated estrogen because dbol is methylated eq

this is not the best scientific type answer but it is true that the estrogen that dbol amortizes into is MUCH stronger than the estrogen test or eq metabolizes into..

The methyl group is chemically attached to a compound to make it orally active. The methyl group gets cleaved off in the process of your body using it.

I don't think the human body is capable of adding methyl groups to estrogen. By your rationale, testosterone propionate would aromatize to estrogen propianate which we know to be untrue.
 
EQ is not like tren. EQ seems to be very mild in terms of sides for most. But I get no anxiety on EQ. Or on tren.

Does paranoia that the cops are comming count? :p
 
argent said:


The methyl group is chemically attached to a compound to make it orally active. The methyl group gets cleaved off in the process of your body using it.

I don't think the human body is capable of adding methyl groups to estrogen. By your rationale, testosterone propionate would aromatize to estrogen propianate which we know to be untrue.

read this:
pasted from http://www.anabolicextreme.com/anabolic/archives/anex_archives_issue10_structure.htm

Dianabol vs. Equipoise
Many claim that Equipoise (boldenone) does not aromatize or give estrogenic side effects, but that dianabol does. This is interesting, because the two molecules are strikingly similar. In fact, at the A ring (where aromatization takes place), they are identical. The only differences are at the D ring. The "R" in the Boldenone molecule is shorthand for a carbon chain (in this case, undecylenate).



Why, then, does Dbol give side effects that Equipoise does not? First, the 17-alpha methyl group affects the way the liver functions, and certain growth factors may be released. Second, the Dbol may actually develop higher concentrations in the blood (spikes right after the pills are taken), and give a higher rate of aromatization than Boldenone. The Boldenone will not give a spike in concentration, since the liver very effectively deactivates it in one pass, and it is released slowly from the ester "depot". The spikes of high concentration of Dbol can give a higher Estradiol concentration over time because the estrogens are not deactivated as quickly as the androgens are in the liver. In fact, the estrogen that will form from Dbol is the 17-alpha mentholated estradiol, which is likely to stay in the system for a long time, because the liver will have a very hard time degrading it. So, the estrogen level can build up over time with the use of Dbol.
 
TheRide said:


Again... anx. is a possible side-effect. Much like acne, gyno, hair loss. Some people are prone, others are not.

the anxiety is probably due to revving up metabolism which explains leaning effect, insomnia & appitite increase as well.

i'm an ecto and experienced the anxiety/insomnia effect before i knew about the urban legend so its not placebo.

iow the urban legend is an urban legend, not the anxiety.
 
Little Rage said:
Mavy:
anxiety on eq is an "urban legend?" That's almost funny

Little Rage, can you please explain this to me ... exactly how boldenone causes anxiety? I would like to know you "reasoning" behind this. I am not going to get into this debate again .... its has been played to death! Some believe it is real, others dont. Others believe its real, but cannot explain 1 reason why.

How can you say that its EQ that causes anxiety in general, and not AAS altogether? What does EQ have in it that would cause this over dbol, test, deca, adrol ... please explain this to me?

ANd please dont say "because its vet gear". Then tell me why dont QV Deca or Enanthate cause these symptoms? They are all vet gear.

One of the biggest reasons I can think of that was mentioned before by someone, is that hormones influence neurotransmitter levels in the brain. Testosterone and its derivatives have a very well established positive correlation with dopamine. When dopamine levels are influenced, this effects neurotransmitter "balance". High dopamine can lead to aggressiveness, anxiety, paranoia, rapid heartbeat, etc. But why then would EQ influence this more than test or dbol, or deca? What makes boldenone have a greater influence?

Increased blood volume and high blood pressure could explain the anxiety attacks as well ... but again there are other drugs that take much more of a toll on your BP, yet the anxiety issue is not associated with these drugs. I would just like you to explain to me why this happens? Thats all. Im not doubting it, I just cant see why people blame this on boldenone, and not aas in general? I personally have never felt anxiety off of EQ, and it is included in most of my cycles. Again , thats not to say it dosent exist (i guess??). I am just more or less looking for an answer why bold would cause it more than other aas.


You see you would be surprised how strong believe something when they are expecting it. The placebo effect is very real my friend.

Sure ... a few people have a few anxiety attacks before (that probably took them before taking EQ anyways), blamed it on the EQ. Then others here of this and are always weary of this when they take there cycle (paranoid). Anything that makes them feel anxious will be blamed on the EQ. Over a long period of time, this reputation becomes associated with EQ. This reputation along with the high hormone levels, extra stress put on your body and whatever else you are on at the time seem to be good ingredients for these anxiety attacks.

Believe what you want, but I doubt that you cannot put up a legit explanation of how boldenone causes this because most of the docs and vets on this board cant either. It has been debated many times.

Regardless of if you think its real, or not, or just a side-effect. It still dosent answer my question to why it has not made it to the human market? Think about it ... there are tuns of other steroids and drugs out there with much worse sides than EQ and are available on the human market.

Mavy
 
I dont think that you should rule out your mind as being responsible ... any more than any other hypothesis. Like I say ... placebo is a real thing.

Doctors in one study successfully eliminated warts by painting them with a brightly colored, inert dye and promising patients the warts would be gone when the color wore off. In a study of asthmatics, researchers found that they could produce dilation of the airways by simply telling people they were inhaling a bronchiodilator, even when they weren't. Patients suffering pain after wisdom-tooth extraction got just as much relief from a fake application of ultrasound as from a real one, so long as both patient and therapist thought the machine was on. Fifty-two percent of the colitis patients treated with placebo in 11 different trials reported feeling better -- and 50 percent of the inflamed intestines actually looked better when assessed with a sigmoidoscope ("The Placebo Prescription" by Margaret Talbot, New York Times Magazine, January 9, 2000)
 
LeanforLife said:
EQ anxiety is how I lost my gf and considered taking my life. It's the compound that made me stop AS for good.

LeanforLife,

That is terrible to here, and I am sorry about that. But how can you really blame it on the EQ. How do you not know it wasnt just the events that were going on in your life? How do you know it wouldnt have happened if you were taking tren, abombs or test for example?
 
Getting back to the original post, Seth Roberts dug up the only journlal entry he could find, and that I have ever seen anyone post regarding boldenone for human consumption. Can someone with medline access PLEASE post this link? I have been dying to read it. It very well could have some answers in it. I would be very interested to read this.



Re: boldenone in humans


quote:
--------------------------------------------------------------------------------
Originally posted by Seth Roberts
This was the only reference that I could find on short notice for the study of boldenone in humans -- Parenabol is a trade name for boldenone undecyclenate.
Seth




The effect of "Parenabol" on patients with osteoporosis.

Melick RA, Baird CW.

PMID: 5493340 [PubMed - indexed for MEDLINE]
--------------------------------------------------------------------------------
 
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