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napsgear
genezapharmateuticals
domestic-supply
puritysourcelabs
Research Chemical SciencesUGFREAKeudomestic
napsgeargenezapharmateuticals domestic-supplypuritysourcelabsResearch Chemical SciencesUGFREAKeudomestic

What is difference between BDO and GHB

JESA1

New member
Ok which one is more potent GHB or BDO (Butanediol). Do both release gh? Also isnt BDO just banned but not scheduled so its just as illegal as tryptophan?
 
1,4-Butanediol, often called "1,4 B" is a chemical closely related to GHB. In the last few years, since GHB has become scheduled federally and in many states, 1,4 B has been sold by many companies as a replacement for GHB. It has similar effects to GHB and is converted in the body into GHB. 1 mL of 1,4 B is approximately equivalent to 1 gram of GHB.

1,4 B is not federally scheduled or controlled though we believe that it is now scheduled in some states. It is not approved by the FDA for human consumption which generally means that possession is federally legal while sale for human consumption may be illegal.

source: erowid.org
 
1,4 is much less euphoric than G or gbl. It also lasts longer. Basically a time-released version since it has to be converted by the liver first. Be careful with this stuff bros. It seriously impairs judgement. More than any other drug I have used in the past. And never drive with it in your system. You might feel fine and then BOOM you pass out.
 
1,4 will not really induce sleep it will just fuck you up and give you heavy spins and make you sick, ghb when taken too much will drive you straight down, and make you pass out (NIETHER WILL KILL YOU, unless you end up mixing ghb with alcohol and/or other state altering drugs). as far as gh increase niether one will do much.
 
What are some of the products you guys are using?(names) It seems that people call EVERYTHING ghb. Blue Nitro,Renewtrient are GBL..EnLiven,and Serenity(I think) are 1,4 B. Nothing is like using real chemical GHB,but the others are close and do get converted(not 100%) I think there is a lot of misinformation about 1,4 B. Its really not as toxic as some think.I helped develop EnLiven in the US and the FDA testing of it was very critical and showed no toxic liver elements when taken in normal amounts.
FYI- Some of you my not know that 1,4 B is found in ice cream cones(trace amounts) as well as other food products..The FDA sent a list of foods which had trace amounts of it. Its(GBL,1,4 B) is illegal to ingest...thats why you see it show up as floor cleaner or solvents....Just be careful with all of it

J:p
 
IMO 1,4-Butanediol is a great sleep aid, provided it is properly dosed.

If you have any questions on how to dose or where to find 1,4-Butanediol, send me an e-mail.

Please include your board name.
 
1,4-butanediol is also found naturally in the human brain.

Morphine is found in cow milk, btw. Seriously.
 
Last edited:
decadense said:
1,4-butanediol is also found naturally in the human brain.

False.

1,4-Butanediol is an industrial chemical used in the manufacture of other organic chemicals. As documented in the scientific literature, 1,4-butanediol is rapidly absorbed and metabolized to g-hydroxybutyric acid (GHBA) in animals and humans. GHBA is a naturally occurring chemical found in the brain and peripheral tissues.

P.S. The difference between GHBA and GHB is that GHBA is an acid and GHB is a salt.

www.ghb-furanone.com
www.eurolabresearch.com
 
goodfellas said:

Identification and quantitation of 1,4-butanediol in mammalian tissues: an alternative biosynthetic pathway for gamma-hydroxybutyric acid.

Barker SA, Snead OC, Poldrugo F, Liu CC, Fish FP, Settine RL.

no abstract

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Studies on the relation of gamma-hydroxybutyric acid (GHB) to gamma-aminobutyric acid (GABA). Evidence that GABA is not the sole source for GHB in rat brain.

Snead OC 3rd, Liu CC, Bearden LJ.

The effects of gamma-aminobutyric acid (GABA)-alpha-oxoglutarate aminotransferase (GABA-T) inhibitors, L-glutamic acid decarboxylase (GAD) inhibitors, and antipetit mal anticonvulsants on gamma-hydroxybutyric acid (GHB) and GABA were studied. Treatment with anticonvulsants and GABA-T inhibitors resulted in an increase in steady-state brain levels of both GHB and GABA. GAD inhibitors produced markedly decreased levels of brain GABA but no change in GHB concentrations. Studies of GHB derived exclusively from GABA showed that GABA-T inhibitors which produced an elevation of steady-state levels of GHB in brain also resulted in a decrease in GABA-derived GHB. Intracerebroventricular (i.c.v.) administration of GABA, putrescine, and 1,4-butanediol all produced significant elevations in brain GHB, but GABA-T inhibitors blocked this effect of GABA and putrescine. These data suggest that there may be another source for GHB in brain in addition to GABA and raise the possibility that 1,4-butanediol may be that source.

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[Toxic role of an endogenous substance: 1,4-butanediol]

[Article in Italian]

Poldrugo F.

no abstract

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Ethanol potentiates the toxic effects of 1,4-butanediol.

Poldrugo F, Barker S, Basa M, Mallardi F, Snead OC.

The simultaneous administration of ethanol increases the mortality rate and tissue damage observed in rats after 1,4-butanediol (1,4-BD). A related increase in tissue 1,4-BD concentration supported the hypothesis of an in vivo competition of the two substances for alcohol dehydrogenase. The clinical implications of the results, in light of the recent discovery of the presence of endogenous 1,4-BD in humans are discussed.
 
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