Want fast weight loss? Answer: TIRATRICOL

[iHulk]

Wanna lose weight fast and speed your metabolism? The answer: Tiratricol.

Most haven't even heard of it since its been banned by the FDA and not many understand it. Well I've been working with the Pharmaceutical company that creates it; its been available overseas for quite some time. Anyway this one of the most effective supplements for weight loss even though it is not prescribed for that reason since too many people abused it. I've personally seen unbelievable results from just 1mg/day. Its a superior and cheaper alternate to taking T3 or T4 directly and definitely a much better option than Disgustingly Nasty Potion other wise known as DNP.

What is it? (see below --all information is provided even health risks)
How much does one take? For how long? 1mg/day for 6-12 weeks.

It makes you sweat a bit more than usual as your body heats up, but man this shit can rip apart that adipose tissue fast and more effectively than anything I've done to cut.

Anyways, here's the info:
Tiratricol (TRIAC)

DESCRIPTION
Tiratricol is an orphan drug for use in combination with levothyroxine to suppress thyroid stimulating hormone in patients with well-differentiated thyroid cancer who are intolerant to adequate doses of levothyroxine alone. Tiratricol is a metabolite of the thyroid hormone triiodothyronine (T3) and has thyroid hormone activity.

Tiratricol is also marketed as a dietary supplement for weight-loss purposes. In November, 1999, the Food and Drug Administration (FDA) warned against consuming products containing tiratricol. This was based on reports of individuals using tiratricol developing side effects, such as fatigue, lethargy, profound weight loss and severe diarrhea. They were also found to have abnormal thyroid function tests. Further action by the FDA is being considered.

Tiratricol is also known as triiododothyroacetic acid, TRIAC, 3,5,3' -triiodothyroacetic acid and [4-(4-hydroxy-3-iodophenoxy)-3,5-di-iodophenyl]acetic acid. Its molecular formula is C14H9I3O4, and its molecular weight is 621.9 daltons.

ACTIONS AND PHARMACOLOGY
ACTIONS
Tiratricol has thyroid hormone activity, including various metabolic effects. It also inhibits the secretion of thyroid-stimulating hormone (TSH) by the pituitary gland.

MECHANISM OF ACTION
The mechanism by which thyroid hormones exert their various actions has not been completely elucidated. Tiratricol is known to act as a feedback inhibitor of TSH secretion by the pituitary gland.

PHARMACOKINETICS
Much is unknown about the pharmacokinetics of tiratricol in humans. The pharmacokinetics of tiratricol appear to be similar to those of thyroxine and triiodothyronine. Tiratricol is absorbed from the small intestine following ingestion. Distribution of tiratricol in the body has not been fully elucidated. Most of this substance appears to be bound to serum proteins, including thyroxine-binding protein and albumin. It appears to be less firmly bound to serum proteins than are T4 and T3. The liver appears to be the major site of degradation of tiratricol. Tiratricol appears to be conjugated with glucuronic acid and sulfuric acid and excreted in the bile. Mainly because it is less tightly bound to serum proteins, tiratricol has a shorter half-life than T4 or T3.

INDICATIONS AND USAGE
The FDA has warned consumers not to purchase tiratricol-containing products due to risk of serious health consequences, including heart attacks and strokes. Tiratricol should be used only under a physician's supervision. Tiratricol is currently used by some as a supplement to burn fat. The doses required to achieve this effect pose significant health risks.

RESEARCH SUMMARY
Tiratricol is an orphan drug. The FDA has determined that it should not be used as a nutritional supplement due to serious potential health risks including heart attack and stroke.

CONTRAINDICATIONS, PRECAUTIONS, ADVERSE REACTIONS
CONTRAINDICATIONS
Tiratricol is contraindicated in those with untreated thyrotoxicosis of any etiology and in those with uncorrected adrenal insufficiency. Thyroid hormones increase tissue demands for adrenocortical hormones and may thereby precipitate acute adrenal crisis. Tiratricol is also contraindicated in those who are hypersensitive to any component of a tiratricol-containing product.

PRECAUTIONS
Tiratricol should only be used for specific approved indications and only under strict medical supervision. Tiratricol should not be used as a treatment for obesity. Tiratricol should be used with extreme caution in those with cardiovascular disorders (including angina, coronary artery disease and hypertension) and in the elderly who have a greater likelihood of occult cardiac disease. Concomitant use of tiratricol and sympathomimetic agents in those with coronary artery disease may increase the risk of coronary insufficiency.

Use of tiratricol in those with concomitant diabetes mellitus, diabetes insipidus or adrenal cortical insufficiency may aggravate the intensity of their symptoms.

ADVERSE REACTIONS
Reported adverse reactions include fatigue, lethargy, profound weight loss and severe diarrhea. Tiratricol has also been reported to cause abnormal thyroid function tests.

INTERACTIONS
DRUGS
Anticoagulants (oral). The hypoprothrombinemic effect of anticoagulants, such as warfarin, may be potentiated.

Sympathomimetic agents. There is a possible increased risk of coronary insufficiency in those with coronary artery disease.

Thyroid drugs (levothyroxine, triiodothyronine, thyroid). Concomitant use of tiratricol with these thyroid drugs is likely to produce additive effects.

LABORATORY TESTS
Tiratricol is likely to alter thyroid function tests, including TSH, T4 and T3.

OVERDOSAGE
There have been no reports of overdosage with tiratricol. Excessive doses of tiratricol theoretically may result in a hypermetabolic state indistinguishable from thyrotoxicosis.

DOSAGE AND ADMINISTRATION
Tiratricol is not recommended for use as a dietary supplement.

LITERATURE
Anon. FDA warns against consuming dietary supplements containing tiratricol. FDA Talk Paper. Nov 21, 2000.

Bracco D, Morin O, Schutz Y, et al. Comparison of the metabolic effects of 3,5,3'-triiodothyroacetic acid and thyroxine. J Clin Endocrin Met. 1993; 77:221-228.

Radetti G, Persani L, Molinaro G, et al. Clinical and hormonal outcome after two years of triiodothyroacetic acid treatment in a child with thyroid hormone resistance. Thyroid. 1997; 7:775-778.

Takeda T, Suzuki S, Liu RT, DeGroot LJ. Triiodothyroacetic acid has unique potential for therapy of resistance to thyroid hormone. J Clin Endocrinol Metab. 1995; 80:2033-2040.

 

[acneman]

Sounds scary but i did a search on ephidrine hcl side effects and found equivalent scary stories
have you tried it or any suppliments that contain it like they were mentioning?

 

[macrophage69alpha]

tiratricol is more suppressive than t3 and less effective for fat loss

it was sold under the name triacana.

syntrax was sued by several women who experienced thryoid failure while using "triax" (there trademark tiratricol)

 

[iHulk]

Sounds scary but i did a search on ephidrine hcl side effects and found equivalent scary stories
have you tried it or any suppliments that contain it like they were mentioning?

I only offer my experience if I personally tried it.. works great. Several others using it reported significant results. I agree they mention some scarey shit but its mild compared to other stuff out there

 

[iHulk]

tiratricol is more suppressive than t3 and less effective for fat loss

it was sold under the name triacana.

syntrax was sued by several women who experienced thryoid failure while using "triax" (there trademark tiratricol)

I totally can't argue with you Macro since you da man; T3 is great for fat loss as well but this is a milder alternative that gives great results.

Syntrax was sued because the women were abusing the drug -- taking over 4mg/day for approx 5 months. Thats a boat load and unnecessary. Also the sue was over a mis-diagnosis of an abnormal thyroid function: hypothyroidism.

And they were subsequently given treatment for the hypothyroidism and that caused even more problems. The effects of Tiratricol caused some doctors to believe that a patient has an overactive ('toxic') thyroid, even though in fact the thyroid has been shut down by tiratricol; improper therapeutic modalities were then employed as a result.

Anyway, just putting it out there.

 

[macrophage69alpha]

J Clin Endocrinol Metab. 1993 Jul;77(1):221-8. Links
Comparison of the metabolic and endocrine effects of 3,5,3'-triiodothyroacetic acid and thyroxine.Bracco D, Morin O, Schutz Y, Liang H, Jequier E, Burger AG.
Institute of Physiology, University of Lausanne, Switzerland.

To test the hypothesis that 3,5,3'-triiodothyroacetic acid (Triac) is more active as a TSH suppressor than on peripheral parameters of thyroid hormone action, the following parameters were studied: basal metabolic rate, sleeping energy expenditure (SEE), sex hormone-binding globulin, and cholesterol. In a double blind trial, 14 subjects received during 3 weeks (phase 1) 180 micrograms T4 or 1700 micrograms Triac daily, divided into 3 doses, to suppress thyroidal secretion. The dosage was doubled for the next 3 weeks (phase 2). Under T4 treatment, TSH reached 0.11 mU/L during phase 1 and less than 0.03 mU/L during phase 2. With Triac, a marked TSH inhibition occurred after 1 week (0.17 mU/L), followed by an escape during the following 2 weeks (0.63 mU/L). During phase 2, an almost complete TSH suppression was obtained (0.03 mU/L). Both Triac doses suppressed endogenous thyroid hormone secretion, as evidenced by T4 and rT3 levels. Both substances induced a 2-fold stimulation of sex hormone-binding globulin during phase 2. Serum cholesterol decreased similarly, without affecting the high/low density lipoprotein ratio. T4 increased SEE by 4.1% and 8.5% during phases 1 and 2. Triac failed to induce the expected peripheral metabolic responses of the thyroid hormones, as demonstrated by an unchanged SEE and basal metabolic rate. These results clearly show a preferential action of Triac on TSH suppression.

 

[iHulk]

what can I say, ihulk is owned. Better get my levels checked.

So that study suggests that SEE and BMR were unchanged and TSH was suppressed. Seen a similar study and they were takin above the normal dosage (in this one they were taking 1700 mcg/day).

In any case, yea its probably not the safest thing but in moderation Ive seen great results.