Testosterone for Andropause HELP.

[presario1]

Hi friends,

Quick info:

51 years old male (my father),
218 ng/dl testosterone level on blood before doing the first shot ;
It is andropause,
Did first injection of testosterone, 250 mg (Testo-Enant), 1 week ago.

After 2 days of the shot started to feel the first mood enhancements that lasted for 2 days; after that the symptoms began to reappear.

At the same time 1 week before getting the fist shot, he was using Lorazepam 1mg before going to sleep. Now he lowered the dose to 0,5 mg Lorazepam a day. At the instruction manual it said that Testo-Enant is generally administered once in 3 weeks. He may go to see the doctor again after 2 days.

Now how do you see this and is it working as it should? Any recommendations you may have (so he can discuss with the doctor)?

How often do you think it should be administered and how long should it take to notice its effects. Some say you need at least 4-6 weeks to fully see the positive effects. Also in my country the only dose available of testosterone is 250 mg in a 2 ml ampoule.

Also what is your experience (dosage, how often, test level etc).

What is the general protocol when starting to treat andropause (how often to do testosterone blood test, checking and other things)?

Thanks in advance

 

[Labtec70]

Hi

I've noticed you've still not had any replies to your post.

I'm not an expert or guru on steroids, but I do know a bit about HRT for men. I had testicular cancer in 2001/2 and was placed on life long Testosterone Replacement Therapy (TRT) in late 2002. In the UK and most of Europe and the USA, patients with low testosterone (LT) receive either testosterone injections, subcutaneous pellet implants, or gels/patches. In England, UK, GP's generally prescribe injections. Testosterone replacement is basically one of three common esters: Cypionate, Enanthate (Enantate), or Sustanon 250. Medical literature often claims testosterone from injection remains active in the system for up to four weeks. With this in mind, physicians generally prescribe an injection every four weeks. In my case this was brought forward to a shot of 250mg (Sustanon 250) every three weeks. While testosterone may remain active for up to four weeks, it certainly doesn't mean it's effective at the four-week point. The half life for most esters is not much over 10 days, if that.

It sounds reasonable to assume your dad did feel a positive effect after a couple of days, since this is around the blood level high-point of the ester. From about day five the levels begin to drop. For an hypothetical example:
Day 1: 250mg shot is slowly relased into blood stream.
Day 4: Blood levels of testosterone peak at 100%.
Day: 6: Blood levels of testosterone are at 70%.
Day 10: Levels are now at the half life value of 45%-50%
Day 21: Levels are now at 24%
Day 24: Levels are now much diminished at 5% but technically still active.

By the four week mark your testosterone is still active but barely traceable. That's why patients tend to notice fluctuations over the course of the weeks following a shot; they are basically responding to high/low levels of fluctuating testosterone. Many guys in the TRT domain and juicers with a lot of knowledge recommend 200mg per week for sustained stability levels of product in the blood-stream. This makes absolute sense to me but you try asking a doctor or specialist endocrinologist for weekly shots and he will - I guarantee - tell you where to go. Unless, that is, you are paying for treatment privately, in which case he'll probably start you off on a shot per week or every 10 days.

Your father should notice an accumalative effect of TRT benefits over several months. Okay, things like mood, mental clarity, sleep, sweating profusely, labido, hot flashes, and energy levels, should be noticeably improved over the first few shots. He may notice after several months of treatment, that the positive effect of the injection begins to drop off after days 12-16. For me, the last week of my shot (3-weekly like your dad) at days 15-21 are the lousiest. My labido drops harshly at this time and my energy levels decline. I also occasionally wake at night sweating like a race-horse. Nevertheless, these effects tend to lessen in severity the longer you're on treatment. I think it's too soon to tell if the dose and therapy is appropriate for your dad. Obviously, if he is testosterone deficient naturally, then he will benefit from TRT should everything else be okay.

Time is of the essence with TRT, so patience is definately a virtue in this instance. Depending on where you are in the world, other therapy options generally exist should injections end up being unsuitable, i.e. pellets, gels, patches, or another type of intramuscular injection. I'm on Sustanon 250 or Nebido (1 shot every 10 weeks) if Sustanon 250 is out of stock.

I hope my reply has helped in some way. There are others in this forum who have much better knowledge of testosterone than me, and hopefully, they will be along at some point to share their view.

All the best to you and your dad!

Craig

 

[oceanview]

But, who wants to go to the doctor every 2 weeks for a shot? Androgel 1.62 is the answer.

 

[Zyglamail]

But, who wants to go to the doctor every 2 weeks for a shot? Androgel 1.62 is the answer.

and who wants to have to put gel on every day OR have your grandaughters grow beards because of exposure to you test gel?

 

[Pound4PoundAAS]

Androgel is horrible. After a few sessions with your doctor, ask to do your shots at home. That's the best and easiest way.

 

[presario1]

Hi

I've noticed you've still not had any replies to your post.

I'm not an expert or guru on steroids, but I do know a bit about HRT for men. I had testicular cancer in 2001/2 and was placed on life long Testosterone Replacement Therapy (TRT) in late 2002. In the UK and most of Europe and the USA, patients with low testosterone (LT) receive either testosterone injections, subcutaneous pellet implants, or gels/patches. In England, UK, GP's generally prescribe injections. Testosterone replacement is basically one of three common esters: Cypionate, Enanthate (Enantate), or Sustanon 250. Medical literature often claims testosterone from injection remains active in the system for up to four weeks. With this in mind, physicians generally prescribe an injection every four weeks. In my case this was brought forward to a shot of 250mg (Sustanon 250) every three weeks. While testosterone may remain active for up to four weeks, it certainly doesn't mean it's effective at the four-week point. The half life for most esters is not much over 10 days, if that.

It sounds reasonable to assume your dad did feel a positive effect after a couple of days, since this is around the blood level high-point of the ester. From about day five the levels begin to drop. For an hypothetical example:
Day 1: 250mg shot is slowly relased into blood stream.
Day 4: Blood levels of testosterone peak at 100%.
Day: 6: Blood levels of testosterone are at 70%.
Day 10: Levels are now at the half life value of 45%-50%
Day 21: Levels are now at 24%
Day 24: Levels are now much diminished at 5% but technically still active.

By the four week mark your testosterone is still active but barely traceable. That's why patients tend to notice fluctuations over the course of the weeks following a shot; they are basically responding to high/low levels of fluctuating testosterone. Many guys in the TRT domain and juicers with a lot of knowledge recommend 200mg per week for sustained stability levels of product in the blood-stream. This makes absolute sense to me but you try asking a doctor or specialist endocrinologist for weekly shots and he will - I guarantee - tell you where to go. Unless, that is, you are paying for treatment privately, in which case he'll probably start you off on a shot per week or every 10 days.

Your father should notice an accumalative effect of TRT benefits over several months. Okay, things like mood, mental clarity, sleep, sweating profusely, labido, hot flashes, and energy levels, should be noticeably improved over the first few shots. He may notice after several months of treatment, that the positive effect of the injection begins to drop off after days 12-16. For me, the last week of my shot (3-weekly like your dad) at days 15-21 are the lousiest. My labido drops harshly at this time and my energy levels decline. I also occasionally wake at night sweating like a race-horse. Nevertheless, these effects tend to lessen in severity the longer you're on treatment. I think it's too soon to tell if the dose and therapy is appropriate for your dad. Obviously, if he is testosterone deficient naturally, then he will benefit from TRT should everything else be okay.

Time is of the essence with TRT, so patience is definately a virtue in this instance. Depending on where you are in the world, other therapy options generally exist should injections end up being unsuitable, i.e. pellets, gels, patches, or another type of intramuscular injection. I'm on Sustanon 250 or Nebido (1 shot every 10 weeks) if Sustanon 250 is out of stock.

I hope my reply has helped in some way. There are others in this forum who have much better knowledge of testosterone than me, and hopefully, they will be along at some point to share their view.

All the best to you and your dad!

Craig

Thank you Craig.

 

[Labtec70]

#pound4poundaas.
Good idea. I do my shots at home now and it is much more convenient. Literally, takes no more than 3 or 4 minutes from getting your kit together to chucking it in your sharps bin.
If he has shots and likes them but doesn't want the hassle of visiting his surgery every couple of weeks, ask the nurse to show you how to self-inject.