subcutaneously vs. IM

[uspsashooter]

I've heard from two different doctors now that they feel sub is the best way to go to administer AAS. The reason being is that the fat provides a better & more controlled release reducing the spikes that usually occur when going intermuscular. Apparently some South African doctor has provided some good data to support this; can't get my hands on this information.

I've always done IM but getting a little tired of sticking myself and was concerned of scar tissue build up since I am a on AAS for life (HRT).

 

[CO B-man]

Subcutaneous means under your skin not in your fat. I dont get this?

 

[pentatonic]

Subcutaneous means under your skin not in your fat. I dont get this?

Subcutaneous injection means under your skin like you said BUT in the fat also.

 

[Swole_2112]

I've heard from two different doctors now that they feel sub is the best way to go to administer AAS. The reason being is that the fat provides a better & more controlled release reducing the spikes that usually occur when going intermuscular. Apparently some South African doctor has provided some good data to support this; can't get my hands on this information.

I've always done IM but getting a little tired of sticking myself and was concerned of scar tissue build up since I am a on AAS for life (HRT).

Try to find this data. I'd be interested in reading it.

 

[sparetire]

a doctor showed me how to give myself sub injections for hcg. The way he showed me, the injection will clearly be below the skin and in the fatty skin. He instructed me to pinch some fat around my stomach and raise it up a bit and put it in that point..

 

[Computer]

Your doctor is probably talking about very small volumes.
Now with the higher doses of roids we bodybuilders need....subQ can't be ideal.
Imagine having a 3ml oil bump under your skin, the risk of abscess due to the slow absorption, passing thick oil through an insulin pin...



Anyway, here is a study :

TABLE TESTOSTERONE LEVELS ACHIEVED WITH SUBCUTANEOUS TESTOSTERONE INJECTIONS
M.B. Greenspan, C.M. Chang
Division of Urology, Department of Surgery, McMaster University,
Hamilton, ON, Canada

Objectives: The preferred technique of androgen replacement has been intramuscular (IM) testosterone, but wide variations in testosterone levels are often seen. Subcutaneous (SC) testosterone injection is a novel approach; however, its physiological effects are unclear. We therefore investigated the sustainability of stable testosterone levels using SC therapy. Patients and methods: Between May and September 2005, we conducted a small pilot study involving 10 male patients with symptomatic late-onset hypogonadism.

Every patient had been stable on TE 200 mg IM for 1 year. Patients were instructed to self-inject with testosterone enanthate (TE) 100 mg SC (DELATESTRYL 200 mg/cc, Theramed Corp, Canada) into the anterior abdomen once weekly. Some patients were down-titrated to 50 mg based on their total testosterone (T) at 4 weeks.

Informed consent was obtained as SC testosterone administration is not officially approved by Health Canada. T levels were measured before and 24 hours after injection during weeks 1, 2, 3, and 4, and 96 hours after injection in week 6 and 8.

At week 12, PSA, CBC, and T levels were measured however; the week 12 data are still being collected.

Results: Prior to initiation of SC therapy, T was 19.14+3.48 nmol/l, hemoglobin 15.8+1.3 g/dl, hematocrit 0.47+0.02, and PSA 1.05+0.65 ng/ml. During the first 4 weeks, there was a steady increase in pre-injection T from 19.14+3.48 to 23.89+9.15 nmol/l (p¼0.1). However, after 8 weeks the post-injection T (25.77+7.67 nmol/l) remained similar to that of week 1 (27.46+12.91 nmol/l). Patients tolerated this therapy with no adverse effects.

Conclusions: A once-week SC injection of 50–100 mg of TE appears to achieve sustainable and stable levels of physiological T. This technique offers fewer physician visits and the use of smaller quantity of medication, thus lower costs. However, the long term clinical and physiological effects of this therapy need further evaluation.