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SARMs and depression

C

colorado1975

New member
Hi Guys....

Quick question...have any of you heard at all about any links to using SARMS and increased depression? Either causing depression or possibly causing medications for depression to not be absorbed properly? The reason I ask is because about 2 weeks after starting my SARMS cycle I have found myself in a really low spot psychologically....I have been on anti-depressents for years (feeling good for over a year) as well as have done few cycles so I don't think its from coming off cycle at the beginning of December....could be just nature and coincidence as well....from what I have read, a lot of people feel better emotionally when taking SARMS....curious of any opinion/thoughts....
My 8 week SARMS cycle is:
1-8 s4: 50 mg day = 25 mg in the AM and 25 mg six hours later.
1-8 osta: 25 mg day dosed once in the AM
1-8 gw: 20 mg day dosed twice a day - 10 mg in the AM and 10 mg twelve hours later

Thanks!
 
thats very strange... i feel my absolute best on sarms... emotionally and physically, its like being on top of the world...
 
Thanks for the responses guys! Its gotta be just 'life' causing it and something else.
 
Its coming off the cycle.. What was your pct like?? What was the cycle that you ran and when exactly did it end.. I for one want to know more.. Thank you and I look forward to helping you...
 
needtogetaas said:
Its coming off the cycle.. What was your pct like?? What was the cycle that you ran and when exactly did it end.. I for one want to know more.. Thank you and I look forward to helping you...
Click to expand...

THank you so much man! I appreciate it!
This was my last cycle:
1-11 test propionate 75 mg day
2-7 trenbolone ace 60 mg day
1-7 masteron 50 mg day
6-11 Avanar 80 mg day / 100 mg day week 10+11
6-11 Provironum 50 mg day / 100 mg day week 10+11
2-11 aromasin 12.5 mg eod
2-7 caber .5 mg e3d
3-11 HCG - human chorionic gonadotropin - - 250iu 2x week

my cycle ended December 12th - since then I have been on 160 mg test cyp/ week with HCG 2x250iu/ week and 2x12.5 mg aromasin/week....in other words I went on TRT so no PCT....my doc did a prescription for 200mg test cyp/month...yes MONTH...which makes zero sense as my levels would be like a roller coaster so I basically am self administering my TRT - going to try and find a doc to supervise though that agrees to something around 100-150mg/week of test. Thoughts?
 
colorado1975 said:
Hi Guys....

Quick question...have any of you heard at all about any links to using SARMS and increased depression? Either causing depression or possibly causing medications for depression to not be absorbed properly? The reason I ask is because about 2 weeks after starting my SARMS cycle I have found myself in a really low spot psychologically....I have been on anti-depressents for years (feeling good for over a year) as well as have done few cycles so I don't think its from coming off cycle at the beginning of December....could be just nature and coincidence as well....from what I have read, a lot of people feel better emotionally when taking SARMS....curious of any opinion/thoughts....
My 8 week SARMS cycle is:
1-8 s4: 50 mg day = 25 mg in the AM and 25 mg six hours later.
1-8 osta: 25 mg day dosed once in the AM
1-8 gw: 20 mg day dosed twice a day - 10 mg in the AM and 10 mg twelve hours later

Thanks!
Click to expand...

How would anyone know since you didnt get bloods?
 
TheRippedReverend said:
How would anyone know since you didnt get bloods?
Click to expand...

I did get blood work. what am I looking for from the results that would indicate a correlation to depression though? I know low T and as well as thyroid levels but not certain what else.
 
Depression? Not to sure but low T could be one.

Really looking at everything. Very little or high estrogen could make you feel like shit too.

Lh
Free test
Total test
Fsh
Estrogen
Prolactin
 
High serum prolactin levels commonly are implicated in depression, anxiety, somnolence, delayed muscular reaction, restless legs syndrome and lack of remorse/impulsivity. Prolactin decreases dopamine levels, inhibits secretion of growth hormone, testosterone and estrogen. Prolactins actions are said to be responsible for about 80% of erection failure in men as well decreased libido in both men/women.

I see you where running tren with nothing added to pct to address this problem. In fact you ran Nolva if I remember correctly right?
Nolvadex Up regulates the PR (it is my theory that this is a major reason Nolvadex and clomid make you feel so damn crappy) So now I think not only do you have High prolactin levels but you have a heightened sensitivity to them...

You can address the HRT problem with your endo or even your self just get on at least 100mg of test a week. I would also Advice 6 weeks of forma-stanzol 5 pumps am and pm every day for the first 4 weeks then drop to 3 and 3 for the second 2 weeks. Along with this I would run some dotinex /5mg every other day the first 2 weeks then every 3 days for the rest of the 6 weeks.

Run the above if you intend on staying on hrt. If not please let me know and I will adjust the program. Otherwise I think this will have you feeling much better in 2 weeks or less. Thanks for posting and sharing with us man and do tell all your friends about the site we could use some extra action around here. :biggrin:
 
needtogetaas said:
High serum prolactin levels commonly are implicated in depression, anxiety, somnolence, delayed muscular reaction, restless legs syndrome and lack of remorse/impulsivity. Prolactin decreases dopamine levels, inhibits secretion of growth hormone, testosterone and estrogen. Prolactins actions are said to be responsible for about 80% of erection failure in men as well decreased libido in both men/women.

I see you where running tren with nothing added to pct to address this problem. In fact you ran Nolva if I remember correctly right?
Nolvadex Up regulates the PR (it is my theory that this is a major reason Nolvadex and clomid make you feel so damn crappy) So now I think not only do you have High prolactin levels but you have a heightened sensitivity to them...

You can address the HRT problem with your endo or even your self just get on at least 100mg of test a week. I would also Advice 6 weeks of forma-stanzol 5 pumps am and pm every day for the first 4 weeks then drop to 3 and 3 for the second 2 weeks. Along with this I would run some dotinex /5mg every other day the first 2 weeks then every 3 days for the rest of the 6 weeks.

Run the above if you intend on staying on hrt. If not please let me know and I will adjust the program. Otherwise I think this will have you feeling much better in 2 weeks or less. Thanks for posting and sharing with us man and do tell all your friends about the site we could use some extra action around here. :biggrin:
Click to expand...

Hi - thanks so much for getting back to me on this. I actually didn't do a PCT as I went straight on HRT after the cycle at 160mg test cyp (2 x 80mg/week) with 250 iu HCG twice a week and 12.5 aromasin twice a week. From the research I did, I thought you did not need a PCT if going on HRT right away....am I mistaken?

Also, I just want to make sure I got your recommendation correctly. You are recommending:
1) at least 100mg test/week (which I'm doing)
2) 6 weeks forma-stanzol (4 weeks - 10 pumps -- 2 weeks 6 pumps)
3) 6 weeks caber- (you said 5mg EOD - did you mean .5mg?)

Thank You Sir!
 
needtogetaas said:
but you did run tren or deca right?
Click to expand...

Tren
This was my last cycle:
1-11 test propionate 75 mg day
2-7 trenbolone ace 60 mg day
1-7 masteron 50 mg day
6-11 Avanar 80 mg day / 100 mg day week 10+11
6-11 Provironum 50 mg day / 100 mg day week 10+11
2-11 aromasin 12.5 mg eod
2-7 caber .5 mg e3d
3-11 HCG - human chorionic gonadotropin - - human chorionic gonadotropin - - 250iu 2x week
 
On the topic of SARMs and depression:
I like you, OP, have manageable depression and I do take meds for it. Last year when running a solo cycle of Ostarine @ 25mg/day I started suffering from depression, anxiety, and worse then usual insomnia about 4 weeks in. Not knowing the cause, I was worried that my natural testosterone had been suppressed and this might have been causing the symptoms of depression. I stopped using Ostarine and the depression subsided.

I don't know why it happened in my case, but I attribute the onset of depression to suppressed testosterone. I know we would all love it if SARMS didn't affect the HPTA, but they clearly do. To what degree is a different conversation.
 
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