Proviron: Hair loss mechanism

[mmk64]

Mention the drug proviron (mesterolone) and one of the first things that pops into people's heads is the fear of hairs popping off of their heads. Especially those prone to MPB (like yours truly). Since this drug is a derivative of DHT, which is known to accelerate hair loss, everyone is claiming that this mimicking effect is directly causing shedding. Everyone claims that taking a 5ar inhibitor like finasteride will not protect your hair, since proviron is already 5a-reduced. Well I have a theory that goes against this, and may protect proviron users from hairloss (independently of topical ketoconazole, spironolactone, and what have you).

While taking finasteride will not directly affect the proviron, it will reduce your natural DHT levels. How is this beneficial? The sole fact that proviron has been shown to have a much higher affinity for SHBG, with DHT coming in 2nd place! So while proviron has been blamed for directly attacking hair follicles in a way that mimics your natural DHT, I believe that all it is doing is enabling your DHT to do so instead. By binding so strongly to SHBG, proviron is not only displacing testosterone but also DHT. So as free DHT levels increase (which is also exacerbated by higher conversion from now increased free test levels), hair loss occurs. By taking finasteride with proviron, you offset this increase in active DHT levels that is responsible for hair loss.

My personal experience confirms the theory. I'm currently on 400mg test plus 600mg EQ (both well kicked in), and decided to throw in 50mg proviron ED to increase free test levels/libido. Before the proviron I had no itchy scalp. A day after throwing in the proviron, it started itching like crazy and I started losing some hair. I have now added 1.25mg finasteride every day and no more itchy scalp.

What do you guys think of my theory?

 

[C.K.]

why the hell would you take an anti androgen best way to kill gains on cycle if you get sides from certain things just try to stay away from them simple as that i can run 100 mg winny, proviron, mast or test a day and have no problem with hair loss only thing that makes me shed is tren... if anything use a topical like nizoral or nioxin shampoo

 

[mmk64]

why the hell would you take an anti androgen best way to kill gains on cycle if you get sides from certain things just try to stay away from them simple as that i can run 100 mg winny, proviron, mast or test a day and have no problem with hair loss only thing that makes me shed is tren... if anything use a topical like nizoral or nioxin shampoo

Wait what? Who said anything about taking an anti-androgen?

 

[C.K.]

dht = androgen blocking it gives way to even worse sides like limp dick and gyno

 

[mmk64]

dht = androgen blocking it gives way to even worse sides like limp dick and gyno

Wrong. DHT is a very strong androgen, so how can it be androgen blocking. Spironolactone, on the other hand, is an androgen blocker. DHT = estrogen blocking. The proviron will replace DHT's role and then some. That is why I don't advise finasteride without a DHT derivative taken with it.

 

[C.K.]

dht = androgen... blocking it gives way to even worse sides like limp dick and gyno

run on sentence my bad

 

[mmk64]

dht = androgen... blocking it gives way to even worse sides like limp dick and gyno

run on sentence my bad

Oh gotcha, my bad . But that is true only if you finasteride alone without a DHT derivative. When adding proviron, proviron acts like DHT (binding to SHBG as well as the aromatase enzyme) which prevents the sides you mentioned. That's my guess anyways. So yeah, like you said it is possible just to avoid a drug like proviron if it causes hairloss..but you can first try something like this if you really like the other effects

 

[C.K.]

I'd rather be bald then impotent lol...

 

[mmk64]

I'd rather be bald then impotent lol...

But what if your lack of hair hurt your game? Then you're left horny without as many girls to bang! . Haha. I'm taking proviron with finasteride and every time I wake up in the middle of the night I have a boner lol. Ran 500mg test alone before and that never happened. So far so good, we'll see if it changes

 

[bigpokey]

interesting theory for ppl like me that take finasteride, im wondering if i take like 5-10mg of dbol everyday if that would minimize the side effects of finasteride without costing me my hair