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norcalbengal
Member
I was told to go IM for gaining more muscle mass, and Sub-Q for leaning out. For mass...which way do you go?
IM- Intra-musclular
Sub-Q- Subcutaneous
IM- Intra-musclular
Sub-Q- Subcutaneous
Poll: GH Users, Inject IM or Sub-Q?
- Thread starter norcalbengal
- Start date
IM will result in slower release while SC gives a quicker release. Quicker release results in a quick spike in IGF-1 while the slower release (IM) approach results in a sustained steady IGF-1 production. Or so the story goes...
Either approach is probably effective but the pulsate (SC) approach is what your body is designed to respond to. Also, keep in mind that SC results in something like 80% bio-availability of the GH while IM yeilds more like 67% and those are best case bio-avail #'s as I have read they can be as low as 60% and 40% for SC vs. IM.
Either approach is probably effective but the pulsate (SC) approach is what your body is designed to respond to. Also, keep in mind that SC results in something like 80% bio-availability of the GH while IM yeilds more like 67% and those are best case bio-avail #'s as I have read they can be as low as 60% and 40% for SC vs. IM.
norcalbengal
Member
thx9000,
So basically, if I injected immediately after working out by sub-q I would have the best results. My problem is I dont get to work out until 7pm...If I took the GH after, would interfere with my own natural pituary release at night?
So I was told to go IM mornings, because the IGF is released throughout the day, then by bedtime my normal Gh is still released while I sleep. What do you think???
So basically, if I injected immediately after working out by sub-q I would have the best results. My problem is I dont get to work out until 7pm...If I took the GH after, would interfere with my own natural pituary release at night?
So I was told to go IM mornings, because the IGF is released throughout the day, then by bedtime my normal Gh is still released while I sleep. What do you think???
gh.jpg
Ok norcalbengal. Here's the FACTS. Take a look and tell me if you see any reason to inject IM. Also, this should answer your questions about when to inject:
Ok norcalbengal. Here's the FACTS. Take a look and tell me if you see any reason to inject IM. Also, this should answer your questions about when to inject:
T
thehound
Guest
I use GH EOD ( saizene ) and I can tell you for certain,
Sub-Q in the ab above the belly button to the left or
right, is the way to go.
Just pull out your skin as far as it will go w/o any discomfort,
than inject at an angle into the pulled skin, you won't feel
anything.
Good Luck.
Sub-Q in the ab above the belly button to the left or
right, is the way to go.
Just pull out your skin as far as it will go w/o any discomfort,
than inject at an angle into the pulled skin, you won't feel
anything.
Good Luck.
Oops
Last edited:
SC is the way to go. I have never tried to do it IM. SubQ works very well for me. I'm 215 at 5%bf.
thx9000 were did you get that information? The bio-availble numbers are right, but IM would give a faster release as it is directly into the bloodstream. SubQ release slower. i think I know were you got that info, as I remeber reading it too. The same read also has some info about IV GH use?
thx9000 were did you get that information? The bio-availble numbers are right, but IM would give a faster release as it is directly into the bloodstream. SubQ release slower. i think I know were you got that info, as I remeber reading it too. The same read also has some info about IV GH use?
The chart is from Genetech research.
supreme
New member
IM:
For someone who is <200 lbs, is there any reason to bump up from the 1.8 Nutropin Depot kits to the 2.2. Been using the 1.8 for 6 months, thinking about going to 2.2 or will the sides be too much?? So far only side numbness / tingilng in hands - but this can also be do to thoracic outlet syndrome - my shoulder are all !$%% up !! from hockey (hence tryimg to heal with GH)
S
For someone who is <200 lbs, is there any reason to bump up from the 1.8 Nutropin Depot kits to the 2.2. Been using the 1.8 for 6 months, thinking about going to 2.2 or will the sides be too much?? So far only side numbness / tingilng in hands - but this can also be do to thoracic outlet syndrome - my shoulder are all !$%% up !! from hockey (hence tryimg to heal with GH)
S
supersonic007
New member
ok- just got out the pharmacological insert that comes with my Saizen, so this is a direct quote, exactly as is:
Metabolism- The metabolic fate of somatropin involves classical protein catabolism in both the liver and kidneys. In renal cells, at least a portion of the breakdown products is trturned to the systemic circulation. The mean half life of intravenous somatropin in normal males is 0.6 hours, whereas subcutaneously and intramuscularly administered somatropin has a half-life of 1.75 and 3.4 hours, respectively. The longer half life observed after subcutaneous or intramuscular administration is due to slow absorbtion from the injection site.
Metabolism- The metabolic fate of somatropin involves classical protein catabolism in both the liver and kidneys. In renal cells, at least a portion of the breakdown products is trturned to the systemic circulation. The mean half life of intravenous somatropin in normal males is 0.6 hours, whereas subcutaneously and intramuscularly administered somatropin has a half-life of 1.75 and 3.4 hours, respectively. The longer half life observed after subcutaneous or intramuscular administration is due to slow absorbtion from the injection site.
supersonic007
New member
also from insert under "pharmacokinetics":
Absorbtion - The absolute bioavailability of recombinant human growth hormone (r-hGH) after subcutaneous administration ranges between 70% and 90%.
I tend to think that SB enters the bloodstream quicker than IM.
Absorbtion - The absolute bioavailability of recombinant human growth hormone (r-hGH) after subcutaneous administration ranges between 70% and 90%.
I tend to think that SB enters the bloodstream quicker than IM.
I think the dose for GH is more dependent on age and goals than it is on body weight. Older guys who are at the low end of production seem to tolerate higher doses better than younger guys at the high end. I've gone as high as 12iu a day w/o sides.
I use the Depot as well (great product), and don't really notice much difference between the 18mg kit or the 22 mg. If the numbness is from the GH, you are likely near your tolerance level. BTW, I think the Nutropin may be overdosed or better in some way than other brands. I'm getting 4iu a day results from 1.8iu Depot. Makes the kit price seem quite reasonable.
I use the Depot as well (great product), and don't really notice much difference between the 18mg kit or the 22 mg. If the numbness is from the GH, you are likely near your tolerance level. BTW, I think the Nutropin may be overdosed or better in some way than other brands. I'm getting 4iu a day results from 1.8iu Depot. Makes the kit price seem quite reasonable.
supreme
New member
Thanks IM - if your getting 4 I.U. results then I'll save the cash, stick with 1.8 kit and use the xtra for some other goodies
I'm just at the 6 month mark, so I guess I'll really start to see the effects soon.
Thanks
S
So not to be a thread whore, guys I seem to remeber reading some posts, in fact they may have been by IM that intra-m GH can cause local tissue atrophy. I know for a fact Sub-q causes localized fat loss - I injected directly into my outer pecs to get rid of some stubborn fat, and I now have these small dimples on the lower abs from injectng the Depot kits - seems to eat away local fat deposits
S
S
I'm just at the 6 month mark, so I guess I'll really start to see the effects soon.
Thanks
S
So not to be a thread whore, guys I seem to remeber reading some posts, in fact they may have been by IM that intra-m GH can cause local tissue atrophy. I know for a fact Sub-q causes localized fat loss - I injected directly into my outer pecs to get rid of some stubborn fat, and I now have these small dimples on the lower abs from injectng the Depot kits - seems to eat away local fat deposits
S
S
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