I am familiar with the generic vs proprietary name, I meant to ask why it would need to run in a trial of 4 weeks...why 4? With the 1/2 life being 3 days, what good would it do to keep it down to 4 weeks? You're either going to have sides by then or you're not. If not, keep going, if so, you shoulda stopped weeks ago when they appeared. That was my only point in asking that. I see your point about "time" though. I'm just not sure 4 vs 12 weeks is a huge deal. 4 weeks vs a few years (like puberty) might call for more concern.