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Dedication777
New member
So been doing some research on my gyno problem, and found out several people have successfully use masteron p/e to eliminate gyno?
Anyone ever tried this, heard of this or have anything to throw in?? If so what was your results?
This is too back up my research a bit.
Masteron (Drostanolone Propionate) is perhaps one of the more 'exotic' androgenic / anabolic steroids (AAS) that may be used by an athlete. Originally it was developed and used as an anti-estrogen (under the name Masteril) for the treatment of breast cancer. It was largely used in combination with the SERM (Selective Estrogen Receptor Modulator) Tamoxifen (aka Nolvadex) for the treatment of breast cancer, and did give a significant decrease in estrogen levels in women undergoing such treatment. It is not much used these days for such purposes, for varying reasons, however for many athletes including competitive bodybuilders in particular; Masteron remains a rather unsung favourite of AS medicines.
The fact that Masteron was being used as an anti-estrogen goes to suggest quite a lot about some properties Masteron possesses. Masteron is a derivative of DHT (dihydrotestosterone) and does not convert to estrogen through means of aromatisation. It is thought that the anti-estrogenic properties of Masteron may be in part to do with either an inhibition in some way of the aromatase enzyme or an interaction with estrogen itself in a way which blocks receptor binding of the estrogen. Either way, this would put Masteron as a useful tool for the AS user who uses compounds that convert to estrogen (which most AS users do, considering testosterone is the main basis of most cycles). By inhibiting the aromatase enzyme, Masteron would be in effect blocking the conversion of free testosterone to estrogen by the aromatisation pathway. This would not only serve to marginally increase the amounts of active free testosterone in circulation (thus giving a greater effect of the testosterone over a Masteron-free system), but it would also negate the side-effects that result from high levels of estrogen due to aromatisation. Such side effects include the development of gynecomastia and water retention/bloating. Conversely, if Masteron actually blocks the binding of estrogen to the estrogen receptor (ER) in some way, although aromatisation of testosterone may occur, its effects would be limited due to the inability of the estrogen to bind to the ER. Thus through this mechanism, the effects of excess estrogen production through aromatisation would also be limited by use of Masteron.
Sent from dedication!
Anyone ever tried this, heard of this or have anything to throw in?? If so what was your results?
This is too back up my research a bit.
Masteron (Drostanolone Propionate) is perhaps one of the more 'exotic' androgenic / anabolic steroids (AAS) that may be used by an athlete. Originally it was developed and used as an anti-estrogen (under the name Masteril) for the treatment of breast cancer. It was largely used in combination with the SERM (Selective Estrogen Receptor Modulator) Tamoxifen (aka Nolvadex) for the treatment of breast cancer, and did give a significant decrease in estrogen levels in women undergoing such treatment. It is not much used these days for such purposes, for varying reasons, however for many athletes including competitive bodybuilders in particular; Masteron remains a rather unsung favourite of AS medicines.
The fact that Masteron was being used as an anti-estrogen goes to suggest quite a lot about some properties Masteron possesses. Masteron is a derivative of DHT (dihydrotestosterone) and does not convert to estrogen through means of aromatisation. It is thought that the anti-estrogenic properties of Masteron may be in part to do with either an inhibition in some way of the aromatase enzyme or an interaction with estrogen itself in a way which blocks receptor binding of the estrogen. Either way, this would put Masteron as a useful tool for the AS user who uses compounds that convert to estrogen (which most AS users do, considering testosterone is the main basis of most cycles). By inhibiting the aromatase enzyme, Masteron would be in effect blocking the conversion of free testosterone to estrogen by the aromatisation pathway. This would not only serve to marginally increase the amounts of active free testosterone in circulation (thus giving a greater effect of the testosterone over a Masteron-free system), but it would also negate the side-effects that result from high levels of estrogen due to aromatisation. Such side effects include the development of gynecomastia and water retention/bloating. Conversely, if Masteron actually blocks the binding of estrogen to the estrogen receptor (ER) in some way, although aromatisation of testosterone may occur, its effects would be limited due to the inability of the estrogen to bind to the ER. Thus through this mechanism, the effects of excess estrogen production through aromatisation would also be limited by use of Masteron.
Sent from dedication!
