Musixtc:
No te voy a discutir tu drogadicción. Si estar fuera de la realidad te hace feliz, bien por ti. En lo particular, me gusta estar con mis 5 sentidos funcionando normalmente y con los pies bien plantados en la tierra. A mi cerebro ni con el pétalo de una rosa. Más bien piensa que beneficios te da, ya que no se me ocurre ninguno. De todos modos, aunque tengo la impresión que será inútil, te presento estos dos artículos del LSD:
1: Neuropsychopharmacology 2002 May;26(5):634-42
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A Single Dose of Lysergic Acid Diethylamide Influences Gene Expression Patterns within the Mammalian Brain.
Nichols CD, Sanders-Bush E.
Department of Pharmacology, Vanderbilt University School of Medicine, 37232, Nashville, TN, USA
Hallucinogenic drugs such as lysergic acid diethylamide (LSD) have profound effects on humans including hallucinations and detachment from reality. These remarkable behavioral effects have many similarities to the debilitating symptoms of neuropsychiatric disorders such as schizophrenia. The effects of hallucinogens are thought to be mediated by serotonin receptor activation; however, how these drugs elicit the unusual behavioral effects remains largely a mystery, despite much research. We have undertaken the first comprehensive analysis of gene expression influenced by acute LSD administration in the mammalian brain. These studies represent a novel approach to elucidate the mechanism of action of this class of drugs. We have identified a number of genes that are predicted to be involved in the processes of synaptic plasticity, glutamatergic signaling and cytoskeletal architecture. Understanding these molecular events will lead to new insights into the etiology of disorders whose behavioral symptoms resemble the temporary effects of hallucinogenic drugs, and also may ultimately result in new therapies.
PMID: 11927188 [PubMed - in process]
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1: Int J Addict 1981 Apr;16(3):527-40
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Multiple drug abuse involving nonopiate, nonalcoholic substances. II. Physical damage, long-term psychological effects and treatment approaches and success.
Kornblith AB.
A review of the literature of multiple drug abuse involving two or more drug categories where at least one is a nonopiate, nonalcoholic substance (MDA NONA) suggested the possibility that sedative-hypnotics were the culpable agent for neuropsychological deficits in this group. Individually, amphetamines and hallucinogens, primarily LSD, have been associated with long-term psychological disturbance. While many abusers of these drugs who develop psychoses have been documented to be emotionally disturbed prior to drug usage, indicating that the drug exacerbated a prepsychotic condition, other abusers have no such history, indicating a drug-induced psychosis. Current treatment approaches appear to be ineffective for MDA-NONA abusers, as indicated by poor retention rates and relapse to drug use.
Publication Types:
Review
PMID: 7024146 [PubMed - indexed for MEDLINE]
Saludos.