We all respond differently. I can only work each bodypart once a week without overtraining and if I don't blast it into oblivion, I will lose strength and size. I don't do many sets but the few that I do are very intense. For years I worked out more like Arnold, doing the mulitiple sets long workouts each bodypart twice a week. When I switched to my current workout it worked better. I change it up every now and then with different exercises and such. I'm willing to try just about anything, nothing set in stone. Well, I take that back. High rep drop sets on legs, forget it. Can't take that pain anymore.