I'm not an expert, and everyones body is different. With that said, I take it as a theraputic dose...weight loss, cut up, feel younger (LOL) I inject a very small dose 1.5 IU/day in the am Mon-Sat...one day off. Has worked great for me. If you take higher doses, you REALLY must monitor your insulin, and other Thyroid stimulating hormones.
I have a caluculation I can send you if your interested. It is based on your weight.