Yep. This shit has done wonders for me. It's prescription only and usually prescribed for cystic acne. But it works at healing stretch marks because it promotes collagen synthesis. Stretch marks are formed when the skin is stretching too fast for the collagen to keep up. The disgusting scars are a result of not enough collagen.
Vitamin E helps existing stretch marks fade a bit and seems to keep new ones from appearing, but it's not the strongest of "cures."
Mederma is said to be pretty effective, but I don't have any first hand experience with it.