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11/23 NFL Over/Under Colts @ Chargers 8PM ET

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The Colts pursue their fourth straight victory when they travel to Qualcomm Stadium for a prime-time matchup with the Chargers.

Indianapolis held off Houston 33-27 for its third consecutive SU win, but the Colts failed to cover as a hefty nine-point home chalk. QB Peyton Manning (30 of 46, 320 yards, 2 TDs, 0 INTs) led a turnover-free offense, and RB Joseph Addai (22 carries, 105 yards, 1 TD) also had a solid day. The Colts finished with a whopping 474 yards, while allowing 356, and finished with a 34:15-25:45 time-of-possession edge.

San Diego lost to Pittsburgh by a rather ugly 11-10 score, but the Chargers covered as a 4½-point road pup, snapping a three-game ATS skid when the referees waived off Troy Polamalu’s fumble-return TD for the Steelers on the final play of the game –a ruling the league later admitted was incorrect. QB Philip Rivers (15 of 26, 164 yards, 0 TDs, 2 INTs) had a dismal day, committing the game’s only turnovers, and the Chargers finished with just 218 total yards, while allowing 410.

San Diego has cashed in four straight against Indy, including a 28-24 upset as a heavy 10½-point pup in the divisional playoffs last January for its third consecutive SU win in this AFC rivalry. The underdog is on a 5-0 ATS run in this rivalry, and the road team is 4-1 ATS in that span.

The Colts are on ATS skids of 1-4 overall and 2-5 on the road against teams with a losing home record. The Chargers, despite their 4-6 ATS mark this season, remain on a bevy of pointspread hot streaks, including 13-5-1 overall, 6-1-1 against winning teams, 9-2 at Qualcomm, 9-3 after a spread-cover and 19-7-3 after a SU loss.

The over for Indianapolis is on streaks of 4-1 overall, 4-0 on the road, 4-1 after a SU win and 6-2 against the AFC, and the over for San Diego is on runs of 8-3 after a SU loss and 13-6-1 in November. But the total has stayed low in five of the Chargers’ last six games and is on further runs for the Bolts of 5-0 against AFC foes and 4-1 against winning teams.
 
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