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Research Chemical SciencesUGFREAKeudomestic
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Symlin - Pramlintide Experience Anyone?

dc35

New member
Just wondering of anyone on here has any experience with pramlintide acetate? A client of mine was given this by her endocrinologist to assist with weight loss. My client is not overweight. She is 50 and has a body comp of 17% + or -. She is however dieting for a figure competition and shared this with her Dr and he thought this could help her.
The trade name is SYMLIN. In short it is used in type 1 and 2 diabetics to control blood sugar. It slows down the movement of food through your stomach. This of course will affect how fast sugar enters your blood after eating. It states that it is always used with slin however she is not diabetic and is not on slin.

If anyone has any experience with this let me know why your take it and what your experiences have been.

Any info pertaining to this drug would be helpful.

Thanks,
DC
 
A Few Questions, Is your Client Diabetic?were blood tests ran?
I cannot believe he would prescribe this as a diet aid only!Heres more info!
Do not use Symlin if you:

cannot tell when your blood sugar is low (hypoglycemia unawareness).

have a stomach problem called gastroparesis. This is when your stomach does not empty as fast as it should.Do not use if you
are allergic to Symlin or any ingredients in Symlin.
What Are The Risks?
“What Is The Most Important Information About Symlin?”

Low blood sugar (hypoglycemia): Symlin is used with insulin to lower your blood sugar, but your blood sugar may drop too low, especially if you have type 1 diabetes. When starting Symlin, reduce your doses of insulin before meals as recommended by your doctor to reduce the chance of low blood sugar.

Nausea is the most common side effect with Symlin

Other side effects include decreased appetite, vomiting, stomach pain, tiredness, dizziness, or indigestion. Symlin also can cause reactions at the injection site including redness, minor bruising, or pain.

Administer immediately prior to each major meal (containing at least 250 kcal or 30 g of carbohydrate).
Visually inspect solution before withdrawing dose. Do not use if particulate matter, discoloration, or cloudiness noted.
Measure prescribed dose using 0.3 mL U-100 insulin syringe using the following guidelines: For 15 mcg dose: withdraw 0.025 mL or 2.5 units using increment line on U-100 syringe. For 30 mcg dose: withdraw 0.05 mL or 5 units using increment line on U-100 syringe. For 45 mcg dose: withdraw 0.075 mL or 7.5 units using increment line on U-100 syringe. For 60 mcg dose: withdraw 0.1 mL or 10 units using increment line on U-100 syringe. For 120 mcg dose: withdraw 0.2 mL or 20 units using increment line on U-100 syringe.
Administer each dose into abdomen or thigh. Do not administer into arm because of variable absorption. Rotate injection sites. Make injection site distinct from the site chosen for any concomitant insulin injection.
Always administer pramlintide and insulin as separate injections. Do not mix pramlintide with any type of insulin. Always use a new syringe and needle to give pramlintide and insulin injections.
Storage/Stability
Store unopened (not in-use) vial in refrigerator (36° to 46°F). Protect from light and freezing. Discard if vial has been frozen or overheated. Store opened (in-use) vial in refrigerator (36° to 46°F) or at room temperature not exceeding 86°F for up to 30 days. Discard after 30 days.

RADAR
 
No more to the story RADAR. No she is not diabetic. She went in for a regular check of her hormone therapy, surgical menopause, and DR asked if she wanted to try it. I have the box and the slip and have already read what you posted but was just wondering if there was or is something I missed as to why this DR would give her this. He has done a great job with her hormone therapy but based on the pharmocology of this drug I do not understand where he would qualify suggesting this:confused:

She has not taken any and at this point I do not see anything suggesting that she should or where the benfit would be.
I have structured her nutrition and she is all natural, the therapy is just that, no elevated levels.
 
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<p><strong><img src="http://www.elitefitness.com/images/diet-drugs/pramlintide-metreleptin.jpg" alt="Pramlintide Metreleptin" width="300" height="447" hspace="10" align="right" /><a href="http://bodybuilding.elitefitness.com/pramlintide-metreleptin-diet-drug" target="_blank">Pramlintide & Metreleptin Injectable Diet Drug Combo Promotes Massive Weight Loss</a></strong></p> <p>Every new diet drug that comes out is supposedly the next big thing.  However, two new drugs have the potential to shake up the dieting industry. They are Pramlintide and Metreleptin and it appears they can help people drop more pounds than ever before.  And the best part is that they’ll work on burning fat without you having to lift a finger! </p> <p> Weight loss expert Dr. Ken Fujoka stated this fact when he said, “With these new medications, now we're getting what we call double digit weight loss. 10 percent and up.”  Fujoka continued by saying, “So now you're losing 20, 30, and 40 pounds of weight with these new weight loss medications, which really makes the doctor and the patient a lot happier.”</p> <p>The Pramlintide and Metreleptin combo drug that is allowing people to see these double digit losses in weight is made by a company called Amylin.  Their injectable drug doesn’t have a name yet, but it has proven to curb people’s appetites in clinical trials. </p> <p>Here's the link to the full article:</p> <p><a href="http://bodybuilding.elitefitness.com/pramlintide-metreleptin-diet-drug" target="_blank">Pramlintide & Metreleptin Injectable Diet Drug Combo Promotes Massive Weight Loss</a></p>
 
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