modafinil (provigil)

[35ripped]

anyone know where you can buy this stuff online heard it works great. alot of bodybuilders are taking it for alertness and performance.

 

[fulforb]

I thought you can't ask for sources on this board. Try other boards that allow it.

 

[fulforb]

It is becoming ver popular with bodybuilders also. I have a script for it because I have a sleep disorder and have narcolepsy. It is also being prescribed for shift workers last I heard. I see a sleep doctor, I don't know if a GP can prescribe it or not.

 

[ohashi]

Modafinil is not controlled at this moment (at least I don't think so), so it's not really asking for a source. But I guess just to be safe, 35ripped, email me at [email protected]

 

[aznurse]

It is controlled in the U.S.

 

[ohashi]

Interesting. It's not scheduled, however.

 

[fulforb]

Just like Ritilin, it's getting abused a lot by people.

 

[ohashi]

It's non-stimulatory and has low potential for abuse. Who are these "a lot of people?"

 

[gamorrah]

Im going to find the article that my phamacist friend sent me on provigil, basically it stated that rats respond in a similar fashion to provigil as cocaine, and that it is commonly abused by speed freaks: I have heard contradictory information as well, I will post it shortly!

 

[gamorrah]

Im going to find the article that my phamacist friend sent me on provigil, basically it stated that rats respond in a similar fashion to provigil as cocaine, and that it is commonly abused by speed freaks: I have heard contradictory information as well, I will post it shortly!

Im still waiting for the original article, but found this

Evaluation of the cocaine-like discriminative stimulus effects and reinforcing effects of modafinil
by
Gold LH, Balster RL
Department of Pharmacology and Toxicology,
Medical College of Virginia,
Virginia Commonwealth University,
Richmond 23298-0613, USA.
Psychopharmacology (Berl) 1996 Aug; 126(4):286-92

ABSTRACT

Modafinil [(diphenyl-methyl)sulphinyl-2-acetamide] is a novel psychostimulant drug which is effective in the treatment of narcolepsy and idiopathic hypersomnia. It also has neuroprotective effects in animal models of striatal neuropathology. Although the cellular mechanisms of action of modafinil are poorly understood, it has been shown to have a profile of pharmacological effects that differs considerably from that of amphetamine-like stimulants. There is some evidence that modafinil has central alpha 1-adrenergic agonist effects. In the present study modafinil was evaluated for cocaine-like discriminative stimulus effects in rats and for reinforcing effects in rhesus monkeys maintained on intravenous cocaine self-administration. Modafinil, l-ephedrine and d-amphetamine all produced dose dependent increases in cocaine-lever responding, with maximal levels of 67%, 82% and 100%, respectively. Modafinil produced full substitution in four out of the six rats tested while the highest levels of substitution were associated with substantial response rate decreasing effects. Little evidence was obtained that the discriminative stimulus effects of modafinil were produced by alpha 1-adrenergic activation, based upon results of tests performed in combination with prazosin. In the self-administration procedure, modafinil and l-ephedrine functioned as reinforcers in rhesus monkeys. The reinforcing and discriminative stimulus effects of modafinil-required very high doses: modafinil was over 200 times less potent than d-amphetamine and was also less potent than l-ephedrine. These results show that modafinil has some cocaine-like discriminative stimulus effects and, like other abused stimulants, can serve as a reinforcer at high doses.