Posted by Unique on March 06, 1997 at 23:19:50:
First, I am not and never was pissed at you. I am really a very even tempered person that takes most
things in stride (even the HMB didn't really anger me--just hyperbolizing the situation). Anyway you're
cool with me and always have been even though YOUR WRONG about the PPA!
I don't see how you can continue arguing your point when it's such basic biochemistry! Medline has plenty
of studies comparing the various ephedrine (including PPA) alkaloids with each other in terms of effect, potency,
etc. The results: PPA is the strongest of the alkaloids with ephedrine right behind it. PPA is the most
thermogenic of the bunch and this too is shown in Medline studies. I will say this once more that none of the
ephedrine alkaloids have intrinsic adrenergic potential. All of them stimulate the adrenal glands to varying extents
to produce more adrenaline and noradrenaline. Cardiotoxic--yes, some but really no more than ephedrine. PPA is not
intrinsically cardiotoxic but again is so because of its stimulated increase of adrenaline and a concomitant stimulation
of the beta-1 and beta-2 receptors in the heart. Man, this is basic stuff, how can you argue this? Have you even tried
PPA? Someone please come to my defense who has substituted PPA for ephedrine in the normal stack. Please set the record
straight that they have the same basic effect. Think about it--if this stuff is so bad why is the FDA targeting ephedrine
and not PPA (I realize that ephedrine is safe and should be left alone). Believe me, PPA is quite safe and VERY effective.
Keep up the fight
Unique