Posted by Another Jeff on March 27, 1997 at 23:04:17:
In Reply to: Androstene posted by Is it Safe? on March 27, 1997 at 22:00:43:
: Does anyone know if Androstene is safe? Short term? Long term? I've recently started taking it and you definetly get increased strength and agressiveness, but how safe is it? Any side effects?
Here's some info FYI....
Androstenedione is a steroid hormone found in all animals (meat) as well as some plants
(extracts). It is a metabolize of DHEA that serves as a direct precursor (one step removed) in the
bio-synthesis of testosterone. In all mammals, androstenedione is produced in the gonads and
adrenal glands. This oral form of androstenedione is metabolized in the liver to testosterone in
conjunction with a zinc-dependent enzyme.
Androstenedione, when taken orally, will increase blood levels of both androstenedione and
testosterone. Secondly to this increase, effects are often seen such as increased energy, enhanced
recovery and growth from exercise, heightened sexual arousal and function, as well as greater
sense of well being.
According to the German Patent for Androstenedione, 50 mg given orally to men raised plasma
testosterone levels from 140% to 183% of normal. 100 mg of oral androstenedione raised levels
from 211% to 337% of normal.
Blood levels start rising about 15 minutes after oral administration of androstenedione and stay
elevated for around 3 hours. A peak in blood testosterone levels is seen around 1 to 1.5 hours
after ingestion.
Androstenedione is perfectly legal for sale as a nutritional supplement. It is found naturally in
meats as well as some plants. Like DHEA and pregnenolone, it is a key intermediate in the
bio-synthesis of other biologically active steroid hormones.
If androstenedione is taken as directed, and that is once a day prior to physical activity, the
positive benefits can be had without any significant negative feedback response to your natural
testosterone production. This is because the results last only a few hours and that is not enough
time for the pituitary gland to respond. Because blood levels are raised during exercise, a time
when blood flows to muscles is optimized and catabolic conditions prevail, your body's utilization
of the testosterone is maximized.
Androstenedione can also be taken throughout the day at constant intervals to maintain a
consistently higher level of testosterone. This method, although a very effective way to use
androstenedione, may increase the probability of decreased natural testosterone production.
I know this doesn't answer your specific question, but not everyone has seen this (I guess)
Hope it helps someone- AJ